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Database: UniProt
Entry: A0A0E3S4C9_9EURY
LinkDB: A0A0E3S4C9_9EURY
Original site: A0A0E3S4C9_9EURY 
ID   A0A0E3S4C9_9EURY        Unreviewed;        88 AA.
AC   A0A0E3S4C9;
DT   24-JUN-2015, integrated into UniProtKB/TrEMBL.
DT   24-JUN-2015, sequence version 1.
DT   24-JAN-2024, entry version 33.
DE   SubName: Full=Thioredoxin {ECO:0000313|EMBL:AKB74017.1};
GN   ORFNames=MSLAZ_0756 {ECO:0000313|EMBL:AKB74017.1};
OS   Methanosarcina lacustris Z-7289.
OC   Archaea; Euryarchaeota; Stenosarchaea group; Methanomicrobia;
OC   Methanosarcinales; Methanosarcinaceae; Methanosarcina.
OX   NCBI_TaxID=1434111 {ECO:0000313|EMBL:AKB74017.1, ECO:0000313|Proteomes:UP000033072};
RN   [1] {ECO:0000313|EMBL:AKB74017.1, ECO:0000313|Proteomes:UP000033072}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Z-7289 {ECO:0000313|EMBL:AKB74017.1,
RC   ECO:0000313|Proteomes:UP000033072};
RA   Henriksen J.R., Luke J., Reinhart S., Benedict M.N., Youngblut N.D.,
RA   Metcalf M.E., Whitaker R.J., Metcalf W.W.;
RT   "Methanogenic archaea and the global carbon cycle.";
RL   Submitted (JUL-2014) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; CP009515; AKB74017.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A0E3S4C9; -.
DR   STRING; 1434111.MSLAZ_0756; -.
DR   KEGG; mls:MSLAZ_0756; -.
DR   PATRIC; fig|1434111.4.peg.948; -.
DR   HOGENOM; CLU_090389_22_0_2; -.
DR   Proteomes; UP000033072; Chromosome.
DR   GO; GO:0015035; F:protein-disulfide reductase activity; IEA:InterPro.
DR   CDD; cd02947; TRX_family; 1.
DR   Gene3D; 3.40.30.10; Glutaredoxin; 1.
DR   InterPro; IPR005746; Thioredoxin.
DR   InterPro; IPR036249; Thioredoxin-like_sf.
DR   InterPro; IPR017937; Thioredoxin_CS.
DR   InterPro; IPR013766; Thioredoxin_domain.
DR   PANTHER; PTHR45663; GEO12009P1; 1.
DR   PANTHER; PTHR45663:SF11; GEO12009P1; 1.
DR   Pfam; PF00085; Thioredoxin; 1.
DR   PIRSF; PIRSF000077; Thioredoxin; 1.
DR   PRINTS; PR00421; THIOREDOXIN.
DR   SUPFAM; SSF52833; Thioredoxin-like; 1.
DR   PROSITE; PS00194; THIOREDOXIN_1; 1.
DR   PROSITE; PS51352; THIOREDOXIN_2; 1.
PE   4: Predicted;
KW   Disulfide bond {ECO:0000256|ARBA:ARBA00023157,
KW   ECO:0000256|PIRSR:PIRSR000077-4};
KW   Electron transport {ECO:0000256|ARBA:ARBA00022982};
KW   Redox-active center {ECO:0000256|ARBA:ARBA00023284,
KW   ECO:0000256|PIRSR:PIRSR000077-4};
KW   Transport {ECO:0000256|ARBA:ARBA00022448}.
FT   DOMAIN          1..88
FT                   /note="Thioredoxin"
FT                   /evidence="ECO:0000259|PROSITE:PS51352"
FT   ACT_SITE        13
FT                   /note="Nucleophile"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR000077-1"
FT   ACT_SITE        16
FT                   /note="Nucleophile"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR000077-1"
FT   SITE            7
FT                   /note="Deprotonates C-terminal active site Cys"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR000077-1"
FT   SITE            14
FT                   /note="Contributes to redox potential value"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR000077-1"
FT   SITE            15
FT                   /note="Contributes to redox potential value"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR000077-1"
FT   DISULFID        13..16
FT                   /note="Redox-active"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR000077-4"
SQ   SEQUENCE   88 AA;  9933 MW;  8E50264FAEBAF61D CRC64;
     MKPMLLDFSA TWCGPCRMQK PIIEELEKKY GDKVEFKVVD VDENQALASK YSIHAVPTLI
     IEKDGTEVKR FMGVTQGSIL SSELDKIL
//
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