ID A0A0E3S5F6_9EURY Unreviewed; 756 AA.
AC A0A0E3S5F6;
DT 24-JUN-2015, integrated into UniProtKB/TrEMBL.
DT 24-JUN-2015, sequence version 1.
DT 27-MAR-2024, entry version 41.
DE SubName: Full=Lead, cadmium, zinc and mercury transporting ATPase {ECO:0000313|EMBL:AKB76344.1};
DE EC=3.6.3.3 {ECO:0000313|EMBL:AKB76344.1};
DE EC=3.6.3.4 {ECO:0000313|EMBL:AKB76344.1};
DE EC=3.6.3.5 {ECO:0000313|EMBL:AKB76344.1};
GN ORFNames=MSLAZ_3083 {ECO:0000313|EMBL:AKB76344.1};
OS Methanosarcina lacustris Z-7289.
OC Archaea; Euryarchaeota; Stenosarchaea group; Methanomicrobia;
OC Methanosarcinales; Methanosarcinaceae; Methanosarcina.
OX NCBI_TaxID=1434111 {ECO:0000313|EMBL:AKB76344.1, ECO:0000313|Proteomes:UP000033072};
RN [1] {ECO:0000313|EMBL:AKB76344.1, ECO:0000313|Proteomes:UP000033072}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Z-7289 {ECO:0000313|EMBL:AKB76344.1,
RC ECO:0000313|Proteomes:UP000033072};
RA Henriksen J.R., Luke J., Reinhart S., Benedict M.N., Youngblut N.D.,
RA Metcalf M.E., Whitaker R.J., Metcalf W.W.;
RT "Methanogenic archaea and the global carbon cycle.";
RL Submitted (JUL-2014) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; CP009515; AKB76344.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0E3S5F6; -.
DR STRING; 1434111.MSLAZ_3083; -.
DR KEGG; mls:MSLAZ_3083; -.
DR PATRIC; fig|1434111.4.peg.4064; -.
DR HOGENOM; CLU_001771_11_2_2; -.
DR Proteomes; UP000033072; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0019829; F:ATPase-coupled monoatomic cation transmembrane transporter activity; IEA:InterPro.
DR CDD; cd07552; P-type_ATPase_Cu-like; 1.
DR Gene3D; 3.40.1110.10; Calcium-transporting ATPase, cytoplasmic domain N; 1.
DR Gene3D; 2.70.150.10; Calcium-transporting ATPase, cytoplasmic transduction domain A; 1.
DR Gene3D; 3.40.50.1000; HAD superfamily/HAD-like; 1.
DR InterPro; IPR023299; ATPase_P-typ_cyto_dom_N.
DR InterPro; IPR018303; ATPase_P-typ_P_site.
DR InterPro; IPR023298; ATPase_P-typ_TM_dom_sf.
DR InterPro; IPR008250; ATPase_P-typ_transduc_dom_A_sf.
DR InterPro; IPR036412; HAD-like_sf.
DR InterPro; IPR023214; HAD_sf.
DR InterPro; IPR027256; P-typ_ATPase_IB.
DR InterPro; IPR001757; P_typ_ATPase.
DR InterPro; IPR044492; P_typ_ATPase_HD_dom.
DR NCBIfam; TIGR01525; ATPase-IB_hvy; 1.
DR NCBIfam; TIGR01494; ATPase_P-type; 2.
DR PANTHER; PTHR43520; ATP7, ISOFORM B; 1.
DR PANTHER; PTHR43520:SF8; COPPER-TRANSPORTING ATPASE 2; 1.
DR Pfam; PF00122; E1-E2_ATPase; 1.
DR Pfam; PF00702; Hydrolase; 1.
DR PRINTS; PR00119; CATATPASE.
DR SFLD; SFLDS00003; Haloacid_Dehalogenase; 1.
DR SFLD; SFLDF00027; p-type_atpase; 1.
DR SUPFAM; SSF81653; Calcium ATPase, transduction domain A; 1.
DR SUPFAM; SSF81665; Calcium ATPase, transmembrane domain M; 1.
DR SUPFAM; SSF56784; HAD-like; 1.
DR PROSITE; PS00154; ATPASE_E1_E2; 1.
PE 4: Predicted;
KW Hydrolase {ECO:0000313|EMBL:AKB76344.1};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Translocase {ECO:0000256|ARBA:ARBA00022967};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 96..116
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 128..146
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 158..180
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 186..204
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 338..359
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 371..399
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 705..726
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 732..750
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REGION 1..57
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 63..82
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 28..57
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 756 AA; 82026 MW; 03494B9F42ADAD87 CRC64;
MSGNSPEFHD ESGSKPAENM PPEGHSEDQT GHAGEKTQTH EPQEEMKPQG HDKHGEMKLQ
THDQPEGMKH QGHEMSGGKG HEDHHAHMLA DFRKRFIISF ILTFPVLLLS PMIQGFFGFE
LRFPGADILI FLLSSVVYFY GGYPFLKGLK DELAEKSPGM MTLIAVAISV AYFYSSAVVF
GLPGGVFFWE LVTLIDVMLL GHWLEMRSVM GASRALEELV KIMPSVAHLK KNGETVDVGV
DQLKIGDRVL VKPGEKIPVD GTVVEGTSSV NESMLTGESK PVTKKPGNEV IGGSINGEAA
FVVEVKKTGK DTYLNQVVEL VRTAQESKSK TQDLANRAAM YLTIIALTAG ALTFILWSFS
GQELVFALER AVTVMVITCP HALGLAIPLV VAVSTSIAAK SGLLIRDRQA FEKARSLEAV
IFDKTGTLTE GRFGVTDVVS LSGEDDNTNE KMDDKKILSL AASLEASSEH PIARGILESA
REKGIETVQV EKFSSIPGKG IEGIIDGKKF LVVSPGYLEE KGISLNDGKI ESENIESENI
ESENIESEKI EEIKEQGKTV VFLLEGERVL GALALADIIR KESREAISKL KGMGIKCLML
TGDNRYVASW VSRELELDDY FAEVLPHEKA AKVIEVQKQY VTGMVGDGVN DAPALAQADV
GIAIGAGTDV AIETADIVLV KNDPRDVLYI IELSRKTYSK MYQNLLWATG YNVFAIPLAA
GVLYGYGILL SPAIGAVLMS LSTVIVAINA RSLKMG
//
