ID A0A0E3S6F0_9EURY Unreviewed; 342 AA.
AC A0A0E3S6F0;
DT 24-JUN-2015, integrated into UniProtKB/TrEMBL.
DT 24-JUN-2015, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE SubName: Full=3-isopropylmalate dehydrogenase {ECO:0000313|EMBL:AKB76066.1};
DE EC=1.1.1.85 {ECO:0000313|EMBL:AKB76066.1};
GN ORFNames=MSLAZ_2805 {ECO:0000313|EMBL:AKB76066.1};
OS Methanosarcina lacustris Z-7289.
OC Archaea; Euryarchaeota; Stenosarchaea group; Methanomicrobia;
OC Methanosarcinales; Methanosarcinaceae; Methanosarcina.
OX NCBI_TaxID=1434111 {ECO:0000313|EMBL:AKB76066.1, ECO:0000313|Proteomes:UP000033072};
RN [1] {ECO:0000313|EMBL:AKB76066.1, ECO:0000313|Proteomes:UP000033072}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Z-7289 {ECO:0000313|EMBL:AKB76066.1,
RC ECO:0000313|Proteomes:UP000033072};
RA Henriksen J.R., Luke J., Reinhart S., Benedict M.N., Youngblut N.D.,
RA Metcalf M.E., Whitaker R.J., Metcalf W.W.;
RT "Methanogenic archaea and the global carbon cycle.";
RL Submitted (JUL-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the isocitrate and isopropylmalate
CC dehydrogenases family. {ECO:0000256|ARBA:ARBA00007769}.
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DR EMBL; CP009515; AKB76066.1; -; Genomic_DNA.
DR RefSeq; WP_048128068.1; NZ_CP009515.1.
DR AlphaFoldDB; A0A0E3S6F0; -.
DR STRING; 1434111.MSLAZ_2805; -.
DR GeneID; 24807664; -.
DR KEGG; mls:MSLAZ_2805; -.
DR PATRIC; fig|1434111.4.peg.3712; -.
DR HOGENOM; CLU_031953_0_1_2; -.
DR OrthoDB; 6813at2157; -.
DR Proteomes; UP000033072; Chromosome.
DR GO; GO:0003862; F:3-isopropylmalate dehydrogenase activity; IEA:UniProtKB-EC.
DR Gene3D; 3.40.718.10; Isopropylmalate Dehydrogenase; 1.
DR InterPro; IPR024084; IsoPropMal-DH-like_dom.
DR PANTHER; PTHR11835; DECARBOXYLATING DEHYDROGENASES-ISOCITRATE, ISOPROPYLMALATE, TARTRATE; 1.
DR PANTHER; PTHR11835:SF77; ISOCITRATE_ISOPROPYLMALATE DEHYDROGENASE FAMILY PROTEIN; 1.
DR Pfam; PF00180; Iso_dh; 1.
DR SMART; SM01329; Iso_dh; 1.
DR SUPFAM; SSF53659; Isocitrate/Isopropylmalate dehydrogenase-like; 1.
PE 3: Inferred from homology;
KW Oxidoreductase {ECO:0000313|EMBL:AKB76066.1}.
FT DOMAIN 4..333
FT /note="Isopropylmalate dehydrogenase-like"
FT /evidence="ECO:0000259|SMART:SM01329"
SQ SEQUENCE 342 AA; 37220 MW; 8914CFEB9098F283 CRC64;
MTKTAAVIKG DGVGPELVDA MLKVAEAAST DVEFVMCEAG AGWWEQHGGN SLIPDETWQL
LDSSDACFKG PTTTPGGIGS PRSVAVSIRT KYDLYANVRP IKTFPNSNAP LGDVEMVCVR
EGTEGLYIGE EIQLTNDVSI AIRKITRTAS SKIARYAFED AKRRGYDTVV PIHKSNILKL
TCGSFLEEVA KVAQDYPNIE VWPYHIDNIA QQLIKNPQLF NKKVLLSTNL FMDVISEECS
ALVGSIGLIY SANIGTNFAM FEPAHGSAPK YAGQDKVNPV ATVLAGAWML DYLGEKEKSE
AIFKATERVI SEGKYVTYDL GGSAKLSQMT DEIAKYTAEI LK
//
