ID A0A0E3SEQ2_9EURY Unreviewed; 398 AA.
AC A0A0E3SEQ2;
DT 24-JUN-2015, integrated into UniProtKB/TrEMBL.
DT 24-JUN-2015, sequence version 1.
DT 27-MAR-2024, entry version 32.
DE SubName: Full=GTP cyclohydrolase III (Methanopterin) {ECO:0000313|EMBL:AKB79456.1};
GN ORFNames=MSHOH_2973 {ECO:0000313|EMBL:AKB79456.1};
OS Methanosarcina horonobensis HB-1 = JCM 15518.
OC Archaea; Euryarchaeota; Stenosarchaea group; Methanomicrobia;
OC Methanosarcinales; Methanosarcinaceae; Methanosarcina.
OX NCBI_TaxID=1434110 {ECO:0000313|EMBL:AKB79456.1, ECO:0000313|Proteomes:UP000033101};
RN [1] {ECO:0000313|EMBL:AKB79456.1, ECO:0000313|Proteomes:UP000033101}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=HB-1 {ECO:0000313|EMBL:AKB79456.1,
RC ECO:0000313|Proteomes:UP000033101};
RA Henriksen J.R., Luke J., Reinhart S., Benedict M.N., Youngblut N.D.,
RA Metcalf M.E., Whitaker R.J., Metcalf W.W.;
RT "Methanogenic archaea and the global carbon cycle.";
RL Submitted (JUL-2014) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; CP009516; AKB79456.1; -; Genomic_DNA.
DR RefSeq; WP_048141112.1; NZ_CP009516.1.
DR AlphaFoldDB; A0A0E3SEQ2; -.
DR STRING; 1434110.MSHOH_2973; -.
DR GeneID; 24832297; -.
DR KEGG; mhor:MSHOH_2973; -.
DR PATRIC; fig|1434110.4.peg.3835; -.
DR HOGENOM; CLU_003728_2_2_2; -.
DR OrthoDB; 115601at2157; -.
DR Proteomes; UP000033101; Chromosome.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 4.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR InterPro; IPR001440; TPR_1.
DR InterPro; IPR013105; TPR_2.
DR InterPro; IPR019734; TPR_repeat.
DR PANTHER; PTHR44943; CELLULOSE SYNTHASE OPERON PROTEIN C; 1.
DR PANTHER; PTHR44943:SF4; TPR REPEAT-CONTAINING PROTEIN MJ0263; 1.
DR Pfam; PF00515; TPR_1; 5.
DR Pfam; PF13432; TPR_16; 2.
DR Pfam; PF07719; TPR_2; 1.
DR SMART; SM00028; TPR; 10.
DR SUPFAM; SSF48439; Protein prenylyltransferase; 1.
DR SUPFAM; SSF48452; TPR-like; 2.
DR PROSITE; PS50005; TPR; 10.
DR PROSITE; PS50293; TPR_REGION; 6.
PE 4: Predicted;
KW Hydrolase {ECO:0000313|EMBL:AKB79456.1};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW TPR repeat {ECO:0000256|ARBA:ARBA00022803, ECO:0000256|PROSITE-
KW ProRule:PRU00339}.
FT REPEAT 51..84
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REPEAT 85..118
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REPEAT 119..152
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REPEAT 153..186
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REPEAT 187..220
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REPEAT 221..254
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REPEAT 255..288
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REPEAT 289..322
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REPEAT 323..356
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REPEAT 357..390
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REGION 1..33
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..25
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 398 AA; 44834 MW; 9AF785A9F3A8D081 CRC64;
MDSGEPKDKS FEKEGKEKKT ESEEGSVSGD MYVLDDSGSV AKEEVSNEIL AAELNECGLD
LLRLGKFKEA IVAFEKAIEK DPENIYLLNN KAAALESLGK FEEALKLYQE AVKINSEDAD
LWNNMAFSYS QVGEYEKAVD AYGKALELKP DYPNAWYGKA LNLSQAGKYE EAIEAYGKVL
KENSDYKEAW AGMGIALGQM GNYDEAIIAY DKALEIDPGF LEAWYYKGVD LDSLGSFKQA
LKAYEKAVEI DPKNDDAWNN MGIDLENLER YDEAINAFEK AIEINSENSD VWYNKGFTLS
QVQRFEEAVE AYRKAIQLDP EYLEPYSSLG FVLAQLKRFE EALEIYERAL KLDPEAADSW
FGKAICLSFL GREEEAEDAY RKAVEIDPRY AEIGGDIQ
//
