ID A0A0E3SJG9_9EURY Unreviewed; 348 AA.
AC A0A0E3SJG9;
DT 24-JUN-2015, integrated into UniProtKB/TrEMBL.
DT 24-JUN-2015, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE SubName: Full=tRNA-(G10-N2) methyltransferase {ECO:0000313|EMBL:AKB80393.1};
GN ORFNames=MSHOH_3910 {ECO:0000313|EMBL:AKB80393.1};
OS Methanosarcina horonobensis HB-1 = JCM 15518.
OC Archaea; Euryarchaeota; Stenosarchaea group; Methanomicrobia;
OC Methanosarcinales; Methanosarcinaceae; Methanosarcina.
OX NCBI_TaxID=1434110 {ECO:0000313|EMBL:AKB80393.1, ECO:0000313|Proteomes:UP000033101};
RN [1] {ECO:0000313|EMBL:AKB80393.1, ECO:0000313|Proteomes:UP000033101}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=HB-1 {ECO:0000313|EMBL:AKB80393.1,
RC ECO:0000313|Proteomes:UP000033101};
RA Henriksen J.R., Luke J., Reinhart S., Benedict M.N., Youngblut N.D.,
RA Metcalf M.E., Whitaker R.J., Metcalf W.W.;
RT "Methanogenic archaea and the global carbon cycle.";
RL Submitted (JUL-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
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DR EMBL; CP009516; AKB80393.1; -; Genomic_DNA.
DR RefSeq; WP_048142608.1; NZ_CP009516.1.
DR AlphaFoldDB; A0A0E3SJG9; -.
DR STRING; 1434110.MSHOH_3910; -.
DR GeneID; 24833278; -.
DR KEGG; mhor:MSHOH_3910; -.
DR PATRIC; fig|1434110.4.peg.4981; -.
DR HOGENOM; CLU_057819_1_0_2; -.
DR OrthoDB; 7080at2157; -.
DR Proteomes; UP000033101; Chromosome.
DR GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR GO; GO:0006400; P:tRNA modification; IEA:UniProt.
DR CDD; cd02440; AdoMet_MTases; 1.
DR CDD; cd11715; THUMP_AdoMetMT; 1.
DR Gene3D; 3.30.2130.30; -; 1.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR InterPro; IPR002052; DNA_methylase_N6_adenine_CS.
DR InterPro; IPR000241; RlmKL-like_Mtase.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR InterPro; IPR004114; THUMP_dom.
DR PANTHER; PTHR14911; THUMP DOMAIN-CONTAINING; 1.
DR PANTHER; PTHR14911:SF13; TRNA (GUANINE(6)-N2)-METHYLTRANSFERASE THUMP3; 1.
DR Pfam; PF02926; THUMP; 1.
DR Pfam; PF01170; UPF0020; 1.
DR PRINTS; PR00507; N12N6MTFRASE.
DR SMART; SM00981; THUMP; 1.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
DR SUPFAM; SSF143437; THUMP domain-like; 1.
DR PROSITE; PS00092; N6_MTASE; 1.
DR PROSITE; PS51165; THUMP; 1.
PE 4: Predicted;
KW Methyltransferase {ECO:0000256|ARBA:ARBA00022603,
KW ECO:0000313|EMBL:AKB80393.1};
KW RNA-binding {ECO:0000256|PROSITE-ProRule:PRU00529};
KW Transferase {ECO:0000313|EMBL:AKB80393.1}.
FT DOMAIN 53..159
FT /note="THUMP"
FT /evidence="ECO:0000259|PROSITE:PS51165"
SQ SEQUENCE 348 AA; 38396 MW; 53B17CF13FE336C5 CRC64;
MLYAFELSGE HEELPAAEVL ACLKIEELDF RPHVRVDQCL VVDIAGKEED IERTLTGVVT
ERLAMTHHIL KVVGIAESRP ETVLKLAEAF EPAGYIKEGE SFVVRAKRIK HHVDFPCEYL
EQKIGGCIYR KGFRANLKSP DVEFRLILSE KAVLGTLLSS VDRSAYEVRT PQNKPFFHPG
VLMPRVARAL TNLSGIKPGE LFLDPFCGTA GILVEAGLVG ARVIGIDAQE KLVLGAHMNL
EAYKLDYILM EGDACRIPLK DSTIDAVVTD PPYGRSAAIL AGSLEELYSG ALSEIQRVLK
PGGIAVVVSD KAAFEYGEKA GLKVLEIYVQ RVHRSLTRII TIFQKDKN
//
