ID A0A0E3UKB2_9BACT Unreviewed; 433 AA.
AC A0A0E3UKB2;
DT 24-JUN-2015, integrated into UniProtKB/TrEMBL.
DT 24-JUN-2015, sequence version 1.
DT 27-MAR-2024, entry version 40.
DE RecName: Full=Citrate synthase {ECO:0000256|PIRNR:PIRNR001369, ECO:0000256|RuleBase:RU003370};
GN Name=gltA {ECO:0000313|EMBL:AKC84140.1};
GN ORFNames=IMCC26134_12960 {ECO:0000313|EMBL:AKC84140.1};
OS Verrucomicrobia bacterium IMCC26134.
OC Bacteria; Verrucomicrobiota.
OX NCBI_TaxID=1637999 {ECO:0000313|EMBL:AKC84140.1, ECO:0000313|Proteomes:UP000033046};
RN [1] {ECO:0000313|EMBL:AKC84140.1, ECO:0000313|Proteomes:UP000033046}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=IMCC26134 {ECO:0000313|EMBL:AKC84140.1,
RC ECO:0000313|Proteomes:UP000033046};
RA Choi A., Kang I., Cho J.-C.;
RT "Complete genome sequence of Verrucomicrobia strain IMCC26134.";
RL Submitted (APR-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=acetyl-CoA + H2O + oxaloacetate = citrate + CoA + H(+);
CC Xref=Rhea:RHEA:16845, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378,
CC ChEBI:CHEBI:16452, ChEBI:CHEBI:16947, ChEBI:CHEBI:57287,
CC ChEBI:CHEBI:57288; EC=2.3.3.16;
CC Evidence={ECO:0000256|ARBA:ARBA00000308,
CC ECO:0000256|RuleBase:RU003370};
CC -!- PATHWAY: Carbohydrate metabolism; tricarboxylic acid cycle; isocitrate
CC from oxaloacetate: step 1/2. {ECO:0000256|ARBA:ARBA00004751,
CC ECO:0000256|RuleBase:RU003370}.
CC -!- SIMILARITY: Belongs to the citrate synthase family.
CC {ECO:0000256|ARBA:ARBA00010566, ECO:0000256|PIRNR:PIRNR001369,
CC ECO:0000256|RuleBase:RU003406}.
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DR EMBL; CP011265; AKC84140.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0E3UKB2; -.
DR STRING; 1637999.IMCC26134_12960; -.
DR KEGG; vba:IMCC26134_12960; -.
DR PATRIC; fig|1637999.3.peg.2777; -.
DR HOGENOM; CLU_025068_0_0_0; -.
DR OrthoDB; 9800864at2; -.
DR UniPathway; UPA00223; UER00717.
DR Proteomes; UP000033046; Chromosome.
DR GO; GO:0005737; C:cytoplasm; IEA:InterPro.
DR GO; GO:0004108; F:citrate (Si)-synthase activity; IEA:InterPro.
DR GO; GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-UniPathway.
DR CDD; cd06114; EcCS_like; 1.
DR Gene3D; 2.20.28.60; -; 1.
DR Gene3D; 1.10.580.10; Citrate Synthase, domain 1; 1.
DR Gene3D; 1.10.230.10; Cytochrome P450-Terp, domain 2; 1.
DR InterPro; IPR016142; Citrate_synth-like_lrg_a-sub.
DR InterPro; IPR016143; Citrate_synth-like_sm_a-sub.
DR InterPro; IPR002020; Citrate_synthase.
DR InterPro; IPR019810; Citrate_synthase_AS.
DR InterPro; IPR024176; Citrate_synthase_bac-typ.
DR InterPro; IPR036969; Citrate_synthase_sf.
DR InterPro; IPR010953; Citrate_synthase_typ-I.
DR NCBIfam; TIGR01798; cit_synth_I; 1.
DR PANTHER; PTHR42871; CITRATE SYNTHASE; 1.
DR PANTHER; PTHR42871:SF1; CITRATE SYNTHASE; 1.
DR Pfam; PF00285; Citrate_synt; 1.
DR PIRSF; PIRSF001369; Citrate_synth; 1.
DR PRINTS; PR00143; CITRTSNTHASE.
DR SUPFAM; SSF48256; Citrate synthase; 1.
DR PROSITE; PS00480; CITRATE_SYNTHASE; 1.
PE 3: Inferred from homology;
KW Acyltransferase {ECO:0000313|EMBL:AKC84140.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000033046};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000256|PIRNR:PIRNR001369};
KW Tricarboxylic acid cycle {ECO:0000256|ARBA:ARBA00022532,
KW ECO:0000256|RuleBase:RU003370}.
FT ACT_SITE 308
FT /evidence="ECO:0000256|PIRSR:PIRSR001369-1"
FT ACT_SITE 366
FT /evidence="ECO:0000256|PIRSR:PIRSR001369-1"
SQ SEQUENCE 433 AA; 48105 MW; 87B2D0A6085C5F15 CRC64;
MANTATLKLD DKEIQLPVIT GSEGEKAVDI NRLRADTGYI TYDDGFGNTG SCLSKITFID
GETGILRFRG YPIEQLAEHS NFIESSLLVM NGELPTAKER NQFSGLLTQN APLREGLTRF
IQSFPRDAHP MAILSATMNA LGAYYPHLSS NNHQRDLEHF EEAAAIAISK VRTIAAHTYR
VSNGLPFNYP KPSLGYCENF LHLMFSSPYE EYVSTPEVAS ALNLFLLLHA DHEQNCSTST
VRMVASAGAN LFASVSAGIN ALWGPLHGGA NMAVIEMLKN IHADGDDGTR FIAAAKSGKG
DRLMGFGHRV YKNYDPRAKI IKASFYKALT SLGIKDDPLL NIAMKLEECA LSDDYFIQRK
LYPNVDFYSG LIMRALGIPE NMFTVMFAIG RMPGWIAQWR EVAANPKLKI YRPRQIYVGE
PLRNYVPSSQ RKE
//
