ID   A0A0E3WT50_9EURY        Unreviewed;       806 AA.
AC   A0A0E3WT50;
DT   24-JUN-2015, integrated into UniProtKB/TrEMBL.
DT   24-JUN-2015, sequence version 1.
DT   27-MAR-2024, entry version 31.
DE   RecName: Full=histidine kinase {ECO:0000256|ARBA:ARBA00012438};
DE            EC=2.7.13.3 {ECO:0000256|ARBA:ARBA00012438};
GN   ORFNames=MSHOH_1427 {ECO:0000313|EMBL:AKB77910.1};
OS   Methanosarcina horonobensis HB-1 = JCM 15518.
OC   Archaea; Euryarchaeota; Stenosarchaea group; Methanomicrobia;
OC   Methanosarcinales; Methanosarcinaceae; Methanosarcina.
OX   NCBI_TaxID=1434110 {ECO:0000313|EMBL:AKB77910.1, ECO:0000313|Proteomes:UP000033101};
RN   [1] {ECO:0000313|EMBL:AKB77910.1, ECO:0000313|Proteomes:UP000033101}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=HB-1 {ECO:0000313|EMBL:AKB77910.1,
RC   ECO:0000313|Proteomes:UP000033101};
RA   Henriksen J.R., Luke J., Reinhart S., Benedict M.N., Youngblut N.D.,
RA   Metcalf M.E., Whitaker R.J., Metcalf W.W.;
RT   "Methanogenic archaea and the global carbon cycle.";
RL   Submitted (JUL-2014) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L-
CC         histidine.; EC=2.7.13.3; Evidence={ECO:0000256|ARBA:ARBA00000085};
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DR   EMBL; CP009516; AKB77910.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A0E3WT50; -.
DR   STRING; 1434110.MSHOH_1427; -.
DR   KEGG; mhor:MSHOH_1427; -.
DR   PATRIC; fig|1434110.4.peg.1777; -.
DR   HOGENOM; CLU_336998_0_0_2; -.
DR   Proteomes; UP000033101; Chromosome.
DR   GO; GO:0016301; F:kinase activity; IEA:UniProtKB-KW.
DR   GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR   CDD; cd00130; PAS; 4.
DR   Gene3D; 2.10.70.100; -; 1.
DR   Gene3D; 3.30.450.20; PAS domain; 5.
DR   InterPro; IPR025847; MEDS_domain.
DR   InterPro; IPR001610; PAC.
DR   InterPro; IPR000014; PAS.
DR   InterPro; IPR000700; PAS-assoc_C.
DR   InterPro; IPR035965; PAS-like_dom_sf.
DR   InterPro; IPR013767; PAS_fold.
DR   InterPro; IPR013655; PAS_fold_3.
DR   NCBIfam; TIGR00229; sensory_box; 4.
DR   PANTHER; PTHR43304:SF1; PAC DOMAIN-CONTAINING PROTEIN; 1.
DR   PANTHER; PTHR43304; PHYTOCHROME-LIKE PROTEIN CPH1; 1.
DR   Pfam; PF14417; MEDS; 1.
DR   Pfam; PF00989; PAS; 1.
DR   Pfam; PF08447; PAS_3; 1.
DR   Pfam; PF13426; PAS_9; 3.
DR   SMART; SM00086; PAC; 3.
DR   SMART; SM00091; PAS; 5.
DR   SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 5.
DR   PROSITE; PS50113; PAC; 4.
DR   PROSITE; PS50112; PAS; 3.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|SAM:Coils}; Kinase {ECO:0000313|EMBL:AKB77910.1};
KW   Transferase {ECO:0000313|EMBL:AKB77910.1}.
FT   DOMAIN          292..341
FT                   /note="PAC"
FT                   /evidence="ECO:0000259|PROSITE:PS50113"
FT   DOMAIN          441..493
FT                   /note="PAC"
FT                   /evidence="ECO:0000259|PROSITE:PS50113"
FT   DOMAIN          490..559
FT                   /note="PAS"
FT                   /evidence="ECO:0000259|PROSITE:PS50112"
FT   DOMAIN          563..615
FT                   /note="PAC"
FT                   /evidence="ECO:0000259|PROSITE:PS50113"
FT   DOMAIN          616..688
FT                   /note="PAS"
FT                   /evidence="ECO:0000259|PROSITE:PS50112"
FT   DOMAIN          687..739
FT                   /note="PAC"
FT                   /evidence="ECO:0000259|PROSITE:PS50113"
FT   DOMAIN          740..806
FT                   /note="PAS"
FT                   /evidence="ECO:0000259|PROSITE:PS50112"
FT   COILED          332..367
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          599..626
FT                   /evidence="ECO:0000256|SAM:Coils"
SQ   SEQUENCE   806 AA;  93236 MW;  040B83A1AABBB26E CRC64;
     MSNLRVSGVD AVGDIPWGTH FCQFCQTKED LMDIIIPYFR AGLDNNELCV WIISQTFEVE
     EAKETLRSAI PDFNVYLEKG QIELIPYADW FLKKGSFDSQ EVLDSWTEKL NQALISGYDG
     LRATESVCWL EKESWSDFID YEERLDSFLN KNRIILLCTY CHDMCNVTET VDVVSNHEMF
     LIRRKGKWEY IEGFTRKNTT DLKPVQDTLQ ERELRHKVAR AVEVERKRLF DVLDALPAMI
     ALLTPDHHVV FTNRSFREKF GEPGGQHCYE FCFGNTKSCE FCEAYKVLET GQPHHWEVVT
     PDGNVIDVYD IPFTDIDNSP MILEMNIDVT ERKRAEEALK KAYDTLEEKI KERTAELEKS
     YNSLKESQES LAEAQRIAHI GNWEWDVATD EAQWSDEMYR IFGLNPQEPA PCLNEFLNYI
     HPEDRDIIDK IIKKRSEGIS EGIDYRIIRA NGEERVVYTQ TEVIFDEKSI PVRVKGIVQD
     ITERKKSEEK IQSLANIVES SNDAIITKSF DGIITSWNKG AEQVYGYSAE EILGKNIAII
     EPDNRKGEIE QLGEKVKQGE IVHNYETLRL RKDGTIINVS LTLSPVFDSH GKLVSISAIA
     RDTTESKRAE EKLRESEEKY RNIVETSNEG IYFVNDEGKV TFANKMMETS GYSLDEIIGR
     PVWNFVPEES LPVAKKEFEK RRKGISGSYE LKLIRKDGSD IWVHITTKPF FNKKGKFKGY
     LAMMTDITES KKAEEKLRES EEKYRNIVEI ANEGILVIDS ELRITYYNKK LMEMLGYNSE
     EGIGLPIWDF IRKESKASAR QRMENR
//