ID A0A0E3XPB7_MYCCH Unreviewed; 203 AA.
AC A0A0E3XPB7;
DT 24-JUN-2015, integrated into UniProtKB/TrEMBL.
DT 24-JUN-2015, sequence version 1.
DT 27-MAR-2024, entry version 40.
DE SubName: Full=TetR family transcriptional regulator {ECO:0000313|EMBL:AKC39783.1};
DE SubName: Full=TetR/AcrR family transcriptional regulator {ECO:0000313|EMBL:MBF9522444.1};
GN ORFNames=BKG82_25530 {ECO:0000313|EMBL:OHU47708.1}, GR01_16195
GN {ECO:0000313|EMBL:AKC39783.1}, HA136_15985
GN {ECO:0000313|EMBL:MBF9522444.1};
OS Mycobacteroides chelonae (Mycobacterium chelonae).
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Mycobacteriaceae;
OC Mycobacteroides.
OX NCBI_TaxID=1774 {ECO:0000313|EMBL:AKC39783.1, ECO:0000313|Proteomes:UP000033056};
RN [1] {ECO:0000313|EMBL:AKC39783.1, ECO:0000313|Proteomes:UP000033056}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 35752 {ECO:0000313|EMBL:AKC39783.1,
RC ECO:0000313|Proteomes:UP000033056};
RX PubMed=26021923;
RA Hasan N.A., Davidson R.M., de Moura V.C., Garcia B.J., Reynolds P.R.,
RA Epperson L.E., Farias-Hesson E., DeGroote M.A., Jackson M., Strong M.;
RT "Draft Genome Sequence of Mycobacterium chelonae Type Strain ATCC 35752.";
RL Genome Announc. 3:e00536-15(2015).
RN [2] {ECO:0000313|EMBL:OHU47708.1, ECO:0000313|Proteomes:UP000180043}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=15515 {ECO:0000313|EMBL:OHU47708.1,
RC ECO:0000313|Proteomes:UP000180043};
RA Fogelson S.B., Camus A.C., Lorenz W., Vasireddy R., Vasireddy S., Smith T.,
RA Brown-Elliott B.A., Wallace R.J.Jr., Hasan N.A., Reischl U., Sanchez S.;
RT "Evaluation of Human, Veterinary and Environmental Mycobacterium chelonae
RT Isolates by Core Genome Phylogenomic Analysis, Targeted Gene Comparison,
RT and Anti-microbial Susceptibility Patterns: A Tale of Mistaken
RT Identities.";
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EMBL:MBF9522444.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Myco6 {ECO:0000313|EMBL:MBF9522444.1};
RX PubMed=33166284;
RA Gu C.H., Zhao C., Hofstaedter C., Tebas P., Glaser L., Baldassano R.,
RA Bittinger K., Mattei L.M., Bushman F.D.;
RT "Investigating hospital Mycobacterium chelonae infection using whole genome
RT sequencing and hybrid assembly.";
RL PLoS ONE 15:0-e0236533(2020).
RN [4] {ECO:0000313|EMBL:MBF9522444.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Myco6 {ECO:0000313|EMBL:MBF9522444.1};
RA Gu C.H., Zhao C., Bushman F.D.;
RL Submitted (MAR-2020) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; CP010946; AKC39783.1; -; Genomic_DNA.
DR EMBL; JAAOOS010000002; MBF9522444.1; -; Genomic_DNA.
DR EMBL; MLIQ01000032; OHU47708.1; -; Genomic_DNA.
DR RefSeq; WP_046254305.1; NZ_MLIU01000028.1.
DR GeneID; 31680884; -.
DR PATRIC; fig|1774.35.peg.3284; -.
DR HOGENOM; CLU_069356_46_0_11; -.
DR OrthoDB; 5242390at2; -.
DR Proteomes; UP000033056; Chromosome.
DR Proteomes; UP000180043; Unassembled WGS sequence.
DR Proteomes; UP000699007; Unassembled WGS sequence.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:UniProt.
DR Gene3D; 1.10.357.10; Tetracycline Repressor, domain 2; 1.
DR InterPro; IPR023772; DNA-bd_HTH_TetR-type_CS.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR001647; HTH_TetR.
DR InterPro; IPR036271; Tet_transcr_reg_TetR-rel_C_sf.
DR InterPro; IPR041669; TetR_C_15.
DR PANTHER; PTHR30055; HTH-TYPE TRANSCRIPTIONAL REGULATOR RUTR; 1.
DR PANTHER; PTHR30055:SF226; HTH-TYPE TRANSCRIPTIONAL REPRESSOR RV1474C; 1.
DR Pfam; PF17918; TetR_C_15; 1.
DR Pfam; PF00440; TetR_N; 1.
DR PRINTS; PR00455; HTHTETR.
DR SUPFAM; SSF46689; Homeodomain-like; 1.
DR SUPFAM; SSF48498; Tetracyclin repressor-like, C-terminal domain; 1.
DR PROSITE; PS01081; HTH_TETR_1; 1.
DR PROSITE; PS50977; HTH_TETR_2; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|PROSITE-ProRule:PRU00335};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 18..78
FT /note="HTH tetR-type"
FT /evidence="ECO:0000259|PROSITE:PS50977"
FT DNA_BIND 41..60
FT /note="H-T-H motif"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00335"
SQ SEQUENCE 203 AA; 22806 MW; 8A4393C3C5D10066 CRC64;
MLNTRLQPRK QPRQDRAGAT RRRILDAAAH VFADFGYAAG TTNRIAERAD ISIGSLYQYF
PNKDSILVEL MTAHTEEGFA LIQRHLSAGL PNSIEDTLRV FVRAAIDNHR DNPRLHRVLF
EEAPRPPEFL ALLHRSEDAV VAAAETLLAT HPEVRIAETA MAARMVVATI ESLVHRLVAG
PRPVDTQLFE DELVNMLTRY LTH
//
