ID A0A0E3Z227_9GAMM Unreviewed; 630 AA.
AC A0A0E3Z227;
DT 24-JUN-2015, integrated into UniProtKB/TrEMBL.
DT 24-JUN-2015, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=Propionyl-CoA synthetase {ECO:0000313|EMBL:AKC85983.1};
DE EC=6.2.1.17 {ECO:0000313|EMBL:AKC85983.1};
GN Name=prpE {ECO:0000313|EMBL:AKC85983.1};
GN ORFNames=WQ53_03590 {ECO:0000313|EMBL:AKC85983.1};
OS Pseudoxanthomonas suwonensis.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Xanthomonadales;
OC Xanthomonadaceae; Pseudoxanthomonas.
OX NCBI_TaxID=314722 {ECO:0000313|EMBL:AKC85983.1, ECO:0000313|Proteomes:UP000033067};
RN [1] {ECO:0000313|EMBL:AKC85983.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=J1 {ECO:0000313|EMBL:AKC85983.1};
RX PubMed=26067962;
RA Hou L., Jiang J., Xu Z., Zhou Y., Leung F.C.;
RT "Complete Genome Sequence of Pseudoxanthomonas suwonensis Strain J1, a
RT Cellulose-Degrading Bacterium Isolated from Leaf- and Wood-Enriched Soil.";
RL Genome Announc. 3:e00614-15(2015).
CC -!- SIMILARITY: Belongs to the ATP-dependent AMP-binding enzyme family.
CC {ECO:0000256|ARBA:ARBA00006432}.
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DR EMBL; CP011144; AKC85983.1; -; Genomic_DNA.
DR RefSeq; WP_052630489.1; NZ_CP011144.1.
DR AlphaFoldDB; A0A0E3Z227; -.
DR KEGG; psuw:WQ53_03590; -.
DR PATRIC; fig|314722.6.peg.752; -.
DR OrthoDB; 9803968at2; -.
DR Proteomes; UP000033067; Chromosome.
DR GO; GO:0050218; F:propionate-CoA ligase activity; IEA:UniProtKB-EC.
DR GO; GO:0019629; P:propionate catabolic process, 2-methylcitrate cycle; IEA:InterPro.
DR Gene3D; 3.30.300.30; -; 1.
DR Gene3D; 3.40.50.12780; N-terminal domain of ligase-like; 1.
DR InterPro; IPR032387; ACAS_N.
DR InterPro; IPR025110; AMP-bd_C.
DR InterPro; IPR045851; AMP-bd_C_sf.
DR InterPro; IPR020845; AMP-binding_CS.
DR InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR InterPro; IPR042099; ANL_N_sf.
DR InterPro; IPR012694; Propion_PrpE.
DR NCBIfam; TIGR02316; propion_prpE; 1.
DR PANTHER; PTHR43347; ACYL-COA SYNTHETASE; 1.
DR PANTHER; PTHR43347:SF3; ACYL-COA SYNTHETASE SHORT-CHAIN FAMILY MEMBER 3, MITOCHONDRIAL; 1.
DR Pfam; PF16177; ACAS_N; 1.
DR Pfam; PF00501; AMP-binding; 1.
DR Pfam; PF13193; AMP-binding_C; 1.
DR SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 1.
DR PROSITE; PS00455; AMP_BINDING; 1.
PE 3: Inferred from homology;
KW Ligase {ECO:0000313|EMBL:AKC85983.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000033067}.
FT DOMAIN 3..57
FT /note="Acetyl-coenzyme A synthetase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF16177"
FT DOMAIN 59..444
FT /note="AMP-dependent synthetase/ligase"
FT /evidence="ECO:0000259|Pfam:PF00501"
FT DOMAIN 510..588
FT /note="AMP-binding enzyme C-terminal"
FT /evidence="ECO:0000259|Pfam:PF13193"
SQ SEQUENCE 630 AA; 69061 MW; 02E5CB79A34FF627 CRC64;
MRYEDLYRRS IEQPEAFWAE AATAIDWNVP PQRILDYANP PFRKWFVGGT TNLCHNAVDR
HLAERGDQLA LVGWSSETGS VRELTFRQLH REVNTFAAAL QSLGVDRGDR VVVYMPHTVD
AAIAMLACAR IGAVHSVVFG GFASHNLALR IDDARPKVLV CADAGSRGGK VIPFKPMVDE
ALARAEHPPV HVLVVNRGLA GELPMRPGRD VEYGPLREAH AKAEVPVEWL ESNEPSYILY
TSGTTGKPKG VQRDVGGYAV ALALSMWSIY DIRPGQVMFS TSDIGWVVGH SYNVYGPLIA
GATSILYEGL PTSPDPGIWW RICERYGVRT MFSSPTAVRV LKKQDPSWLQ RYDLSRLQYL
FLAGEPLDEP TAGWITGALG KTVIDNYWQT ETGWPVLTLM PGVEMRPVKL GSPGLPSPGY
RLRVIDEATG QDVGPGEKGV LAIQPPLPPG CLTTVWGNDE RFIASYFGHF KELLYSSLDW
AIRDEDGYTF ILGRTDDVIN VAGHRLGTRE IEESVSSHPS VAEAAVIGVH DEVKGQVPVV
FATLKRSDGD AAESAAQMMR TVTEQLGAVA RPSRVYVVNA LPKTRSGKLL RRSLQALAEH
RDPGDLSTLD DPNALEEVRR ALERGADAGG
//
