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Database: UniProt
Entry: A0A0E3ZCY5_9BACT
LinkDB: A0A0E3ZCY5_9BACT
Original site: A0A0E3ZCY5_9BACT 
ID   A0A0E3ZCY5_9BACT        Unreviewed;       285 AA.
AC   A0A0E3ZCY5;
DT   24-JUN-2015, integrated into UniProtKB/TrEMBL.
DT   24-JUN-2015, sequence version 1.
DT   11-DEC-2019, entry version 17.
DE   SubName: Full=Nicotinate-nucleotide pyrophosphorylase {ECO:0000313|EMBL:AKD02754.1};
DE            EC=2.4.2.19 {ECO:0000313|EMBL:AKD02754.1};
GN   ORFNames=PKOR_06005 {ECO:0000313|EMBL:AKD02754.1};
OS   Pontibacter korlensis.
OC   Bacteria; Bacteroidetes; Cytophagia; Cytophagales; Hymenobacteraceae;
OC   Pontibacter.
OX   NCBI_TaxID=400092 {ECO:0000313|EMBL:AKD02754.1, ECO:0000313|Proteomes:UP000033109};
RN   [1] {ECO:0000313|EMBL:AKD02754.1, ECO:0000313|Proteomes:UP000033109}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=X14-1T {ECO:0000313|EMBL:AKD02754.1,
RC   ECO:0000313|Proteomes:UP000033109};
RX   PubMed=26057562; DOI=10.1038/srep10929;
RA   Dai J., Dai W., Qiu C., Yang Z., Zhang Y., Zhou M., Zhang L., Fang C.,
RA   Gao Q., Yang Q., Li X., Wang Z., Wang Z., Jia Z., Chen X.;
RT   "Unraveling adaptation of Pontibacter korlensis to radiation and
RT   infertility in desert through complete genome and comparative
RT   transcriptomic analysis.";
RL   Sci. Rep. 5:10929-10929(2015).
CC   -!- SIMILARITY: Belongs to the NadC/ModD family.
CC       {ECO:0000256|PIRNR:PIRNR006250}.
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DR   EMBL; CP009621; AKD02754.1; -; Genomic_DNA.
DR   RefSeq; WP_046309693.1; NZ_CP009621.1.
DR   EnsemblBacteria; AKD02754; AKD02754; PKOR_06005.
DR   KEGG; pko:PKOR_06005; -.
DR   PATRIC; fig|400092.3.peg.1337; -.
DR   KO; K00767; -.
DR   OrthoDB; 1718114at2; -.
DR   Proteomes; UP000033109; Chromosome.
DR   GO; GO:0004514; F:nicotinate-nucleotide diphosphorylase (carboxylating) activity; IEA:UniProtKB-EC.
DR   GO; GO:0009435; P:NAD biosynthetic process; IEA:InterPro.
DR   CDD; cd01572; QPRTase; 1.
DR   Gene3D; 3.20.20.70; -; 1.
DR   Gene3D; 3.90.1170.20; -; 1.
DR   InterPro; IPR013785; Aldolase_TIM.
DR   InterPro; IPR004393; NadC.
DR   InterPro; IPR027277; NadC/ModD.
DR   InterPro; IPR036068; Nicotinate_pribotase-like_C.
DR   InterPro; IPR037128; Quinolinate_PRibosylTase_N_sf.
DR   InterPro; IPR002638; Quinolinate_PRibosylTrfase_C.
DR   InterPro; IPR022412; Quinolinate_PRibosylTrfase_N.
DR   PANTHER; PTHR32179; PTHR32179; 1.
DR   Pfam; PF01729; QRPTase_C; 1.
DR   Pfam; PF02749; QRPTase_N; 1.
DR   PIRSF; PIRSF006250; NadC_ModD; 1.
DR   SUPFAM; SSF51690; SSF51690; 1.
DR   TIGRFAMs; TIGR00078; nadC; 1.
PE   3: Inferred from homology;
KW   Glycosyltransferase {ECO:0000256|PIRNR:PIRNR006250,
KW   ECO:0000313|EMBL:AKD02754.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000033109};
KW   Transferase {ECO:0000256|PIRNR:PIRNR006250, ECO:0000313|EMBL:AKD02754.1}.
FT   DOMAIN          24..112
FT                   /note="QRPTase_N"
FT                   /evidence="ECO:0000259|Pfam:PF02749"
FT   DOMAIN          114..283
FT                   /note="QRPTase_C"
FT                   /evidence="ECO:0000259|Pfam:PF01729"
FT   REGION          135..137
FT                   /note="Substrate binding"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR006250-1"
FT   REGION          247..249
FT                   /note="Substrate binding"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR006250-1"
FT   REGION          268..270
FT                   /note="Substrate binding"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR006250-1"
FT   BINDING         102
FT                   /note="Substrate"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR006250-1"
FT   BINDING         159
FT                   /note="Substrate"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR006250-1"
FT   BINDING         169
FT                   /note="Substrate"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR006250-1"
FT   BINDING         202
FT                   /note="Substrate"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR006250-1"
FT   BINDING         224
FT                   /note="Substrate"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR006250-1"
SQ   SEQUENCE   285 AA;  31023 MW;  796F29A4FB084FA6 CRC64;
     MKPTYLTETS INEFIAKALA EDVGDGDHSS LAGIPTDAQN QARLLVKGDG VLAGVELAGY
     IFKAVDPGLE LDVKMHDGDR MQRGDVAFTV KGKAQSILTA ERLVLNCMQR MSGIATYTNY
     MASLIEGTGA KLLDTRKTTP NFRLMEKWAV VIGGGHNHRF GLYDMVMLKD NHVDYAGGVN
     AAITATQRYL QEKGKDLKIE VETRNLQEVQ EALETGGIHR IMLDNMSTDM MREAVAMIGG
     KYETEASGGI TEETIRAVAE CGVDYISVGA LTHSNRSIDL SLKAF
//
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