ID A0A0E3ZL31_9BURK Unreviewed; 512 AA.
AC A0A0E3ZL31;
DT 24-JUN-2015, integrated into UniProtKB/TrEMBL.
DT 24-JUN-2015, sequence version 1.
DT 24-JAN-2024, entry version 26.
DE RecName: Full=Exopolyphosphatase {ECO:0000256|ARBA:ARBA00020416};
DE EC=3.6.1.11 {ECO:0000256|ARBA:ARBA00012451};
GN ORFNames=CL55_00008080 {ECO:0000313|EMBL:AKD25141.1};
OS Polynucleobacter duraquae.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Burkholderiaceae; Polynucleobacter.
OX NCBI_TaxID=1835254 {ECO:0000313|EMBL:AKD25141.1, ECO:0000313|Proteomes:UP000061135};
RN [1] {ECO:0000313|EMBL:AKD25141.1, ECO:0000313|Proteomes:UP000061135}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MWH-MoK4 {ECO:0000313|EMBL:AKD25141.1,
RC ECO:0000313|Proteomes:UP000061135};
RA Hahn M.W.;
RT "Genome of Polynucleobacter strain MWH-MoK4.";
RL Submitted (MAR-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=[phosphate](n) + H2O = [phosphate](n-1) + H(+) + phosphate;
CC Xref=Rhea:RHEA:21528, Rhea:RHEA-COMP:9859, Rhea:RHEA-COMP:14279,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:16838,
CC ChEBI:CHEBI:43474; EC=3.6.1.11;
CC Evidence={ECO:0000256|ARBA:ARBA00000209};
CC -!- SIMILARITY: Belongs to the GppA/Ppx family.
CC {ECO:0000256|ARBA:ARBA00007125}.
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DR EMBL; CP007501; AKD25141.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0E3ZL31; -.
DR STRING; 1835254.CL55_00008080; -.
DR KEGG; pdq:CL55_00008080; -.
DR PATRIC; fig|576611.7.peg.818; -.
DR HOGENOM; CLU_025908_4_0_4; -.
DR Proteomes; UP000061135; Chromosome.
DR GO; GO:0004309; F:exopolyphosphatase activity; IEA:UniProtKB-EC.
DR GO; GO:0006793; P:phosphorus metabolic process; IEA:InterPro.
DR Gene3D; 3.30.420.40; -; 1.
DR Gene3D; 3.30.420.150; Exopolyphosphatase. Domain 2; 1.
DR Gene3D; 1.10.3210.10; Hypothetical protein af1432; 1.
DR InterPro; IPR043129; ATPase_NBD.
DR InterPro; IPR022371; Exopolyphosphatase.
DR InterPro; IPR048950; Ppx_GppA_C.
DR InterPro; IPR003695; Ppx_GppA_N.
DR InterPro; IPR030673; PyroPPase_GppA_Ppx.
DR NCBIfam; TIGR03706; exo_poly_only; 1.
DR PANTHER; PTHR30005; EXOPOLYPHOSPHATASE; 1.
DR PANTHER; PTHR30005:SF0; RETROGRADE REGULATION PROTEIN 2; 1.
DR Pfam; PF02541; Ppx-GppA; 1.
DR Pfam; PF21447; Ppx-GppA_III; 1.
DR PIRSF; PIRSF001267; Pyrophosphatase_GppA_Ppx; 1.
DR SUPFAM; SSF53067; Actin-like ATPase domain; 2.
DR SUPFAM; SSF109604; HD-domain/PDEase-like; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000313|EMBL:AKD25141.1}.
FT DOMAIN 39..321
FT /note="Ppx/GppA phosphatase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF02541"
FT DOMAIN 329..496
FT /note="Ppx/GppA phosphatase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF21447"
SQ SEQUENCE 512 AA; 56655 MW; 6BCB77C1D130C564 CRC64;
MALQQNKSLM NATELVAAVD LGSNSFRMLV AQVVKTPSGT QLRPIDTLRE SVRLAAGLTD
NKLLGNDAYQ RGIAAIRRFG ERIRGFDPAN VRAVATNTLR VAKNAPHFIR EAEEALGFPI
EVIAGVEEAR LIYIGAAHEV PAVQGNRLVV DIGGGSTELI IGKGYEPRLM ESLYIGCVSH
SLRFFPKGNI DSHAFKEAEL AARREIQVIS EAYLKAGWKQ VIGSSGTARA LAELIAENNF
NGQIDNADGL ITRDGLRAMK KHLLKYDHIN QVELQGLKDD RRSVWPGGLA IMIAVFDELG
IESMEVTDAA LRIGVLYDLL GRSQHEDMRF VTVEQFMQRY AVDREQAKRV GNLAAEFLAQ
LPKPDEESRA DNIALLQWAA NLHEIGLSIS HNGYHKHSAY IAGNADMPGF SKNDQARLAA
LLIGHTGKLG KLANNASFSD WRMLFCMRLA QVLCRGRSDI NLPKVKVSEH NGDYLVSLSK
DWAREHPLTE FSLQKEAAEW ERIGRPYNIS LK
//
