ID A0A0E3ZTA0_9BACT Unreviewed; 729 AA.
AC A0A0E3ZTA0;
DT 24-JUN-2015, integrated into UniProtKB/TrEMBL.
DT 24-JUN-2015, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE RecName: Full=Site-specific DNA-methyltransferase (adenine-specific) {ECO:0008006|Google:ProtNLM};
GN ORFNames=SD10_01640 {ECO:0000313|EMBL:AKD53795.1};
OS Spirosoma radiotolerans.
OC Bacteria; Bacteroidota; Cytophagia; Cytophagales; Cytophagaceae; Spirosoma.
OX NCBI_TaxID=1379870 {ECO:0000313|EMBL:AKD53795.1, ECO:0000313|Proteomes:UP000033054};
RN [1] {ECO:0000313|EMBL:AKD53795.1, ECO:0000313|Proteomes:UP000033054}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DG5A {ECO:0000313|EMBL:AKD53795.1,
RC ECO:0000313|Proteomes:UP000033054};
RX PubMed=24748440; DOI=10.1007/s00284-014-0584-x;
RA Lee J.J., Srinivasan S., Lim S., Joe M., Im S., Bae S.I., Park K.R.,
RA Han J.H., Park S.H., Joo B.M., Park S.J., Kim M.K.;
RT "Spirosoma radiotolerans sp. nov., a gamma-radiation-resistant bacterium
RT isolated from gamma ray-irradiated soil.";
RL Curr. Microbiol. 69:286-291(2014).
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DR EMBL; CP010429; AKD53795.1; -; Genomic_DNA.
DR RefSeq; WP_046375387.1; NZ_CP010429.1.
DR AlphaFoldDB; A0A0E3ZTA0; -.
DR STRING; 1379870.SD10_01640; -.
DR REBASE; 109624; M.SraDG5AORF1635P.
DR KEGG; srd:SD10_01640; -.
DR PATRIC; fig|1379870.5.peg.359; -.
DR HOGENOM; CLU_008343_1_0_10; -.
DR OrthoDB; 9814572at2; -.
DR Proteomes; UP000033054; Chromosome.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0008170; F:N-methyltransferase activity; IEA:InterPro.
DR GO; GO:0006306; P:DNA methylation; IEA:InterPro.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR InterPro; IPR003356; DNA_methylase_A-5.
DR InterPro; IPR029464; HSDR_N.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR PANTHER; PTHR42998:SF1; TYPE I RESTRICTION ENZYME HINDI METHYLASE SUBUNIT; 1.
DR PANTHER; PTHR42998; TYPE I RESTRICTION ENZYME HINDVIIP M PROTEIN-RELATED; 1.
DR Pfam; PF13588; HSDR_N_2; 1.
DR Pfam; PF02384; N6_Mtase; 1.
DR PRINTS; PR00507; N12N6MTFRASE.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000033054}.
FT DOMAIN 59..167
FT /note="Type I restriction enzyme R protein N-terminal"
FT /evidence="ECO:0000259|Pfam:PF13588"
FT DOMAIN 329..660
FT /note="DNA methylase adenine-specific"
FT /evidence="ECO:0000259|Pfam:PF02384"
SQ SEQUENCE 729 AA; 84286 MW; 4EF21112EB846044 CRC64;
MQYPNIQAIL KGSKFSLSTF KEEEIQFIED RILAHKDKKG NDAYVIECLK RGINLKVTPE
EVVRQIFLHR LLTHYRYPKD RIRVEDMVRF GTDTSKRADI VITQKDRPEA VYIIVELKKP
TAKDGKDQLK TYCNGTGAPL GVWTNGGAVD FYFRKDPNLF DSIRDIPSVN QSIDDIRDSR
FTIWHLITQD QTKTKTLKRI IEEFEDEVLA NAGVDVFEEA FKLIFTKLYD EQKSIEDKKA
INYWLSFNKN KEISDIPEEV TNNFRNLDFR SRGAESDTKK AIDDLFDEAK ENWKGIFPES
AKIELTPSHL QTCVSYLETY KLFNSNLEVV DEAFEYLVNK DSKGDKGQYF TPRYVIDMGV
KMLNPKQDEY IIDTAAGSCG FPVHTIFHVW EQMNPNGANH FTIDQKTPEQ TKYVKEKVFA
IDFDYKAVRV GKTLNLIAGD GETNVLHLNS LDYPRWEADF VENKIWQKQF GKGFDNLAKL
ATKKNEYRNF NFDVLLANPP FAGDIKDQRV IHLFDISRKY EEKEDKTTGK KLTREKGWHE
KISRDVLFIE RNLDMLKDGG RMCVVLPQGR FNNSSDKAIR QFIASRCRIL GVVGLHGNSF
KPHTGTKTSL LFVQKWHPEL CPKQDNYNIF FATQQKEGKD NSGEKLYWAD FSSEALQAIQ
DEITEGKTPT IPDLTTNETE RALKDRFGHP IVYHDLFSTP TQYEGISTPK GITEAFTEFA
KKEQLSFFH
//
