ID   A0A0E3ZWP3_9BACT        Unreviewed;       757 AA.
AC   A0A0E3ZWP3;
DT   24-JUN-2015, integrated into UniProtKB/TrEMBL.
DT   24-JUN-2015, sequence version 1.
DT   24-JAN-2024, entry version 35.
DE   SubName: Full=Penicillin-binding protein {ECO:0000313|EMBL:AKD55900.1};
GN   ORFNames=SD10_14325 {ECO:0000313|EMBL:AKD55900.1};
OS   Spirosoma radiotolerans.
OC   Bacteria; Bacteroidota; Cytophagia; Cytophagales; Cytophagaceae; Spirosoma.
OX   NCBI_TaxID=1379870 {ECO:0000313|EMBL:AKD55900.1, ECO:0000313|Proteomes:UP000033054};
RN   [1] {ECO:0000313|EMBL:AKD55900.1, ECO:0000313|Proteomes:UP000033054}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DG5A {ECO:0000313|EMBL:AKD55900.1,
RC   ECO:0000313|Proteomes:UP000033054};
RX   PubMed=24748440; DOI=10.1007/s00284-014-0584-x;
RA   Lee J.J., Srinivasan S., Lim S., Joe M., Im S., Bae S.I., Park K.R.,
RA   Han J.H., Park S.H., Joo B.M., Park S.J., Kim M.K.;
RT   "Spirosoma radiotolerans sp. nov., a gamma-radiation-resistant bacterium
RT   isolated from gamma ray-irradiated soil.";
RL   Curr. Microbiol. 69:286-291(2014).
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; CP010429; AKD55900.1; -; Genomic_DNA.
DR   RefSeq; WP_046574520.1; NZ_CP010429.1.
DR   AlphaFoldDB; A0A0E3ZWP3; -.
DR   STRING; 1379870.SD10_14325; -.
DR   KEGG; srd:SD10_14325; -.
DR   PATRIC; fig|1379870.5.peg.3115; -.
DR   HOGENOM; CLU_426800_0_0_10; -.
DR   OrthoDB; 9766909at2; -.
DR   Proteomes; UP000033054; Chromosome.
DR   GO; GO:0009274; C:peptidoglycan-based cell wall; IEA:InterPro.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR   GO; GO:0016763; F:pentosyltransferase activity; IEA:InterPro.
DR   GO; GO:0071555; P:cell wall organization; IEA:UniProtKB-KW.
DR   GO; GO:0009252; P:peptidoglycan biosynthetic process; IEA:UniProtKB-KW.
DR   GO; GO:0008360; P:regulation of cell shape; IEA:UniProtKB-KW.
DR   Gene3D; 1.10.3810.10; Biosynthetic peptidoglycan transglycosylase-like; 1.
DR   InterPro; IPR001264; Glyco_trans_51.
DR   InterPro; IPR023346; Lysozyme-like_dom_sf.
DR   InterPro; IPR036950; PBP_transglycosylase.
DR   InterPro; IPR011812; Pep_trsgly.
DR   PANTHER; PTHR30400:SF0; BIOSYNTHETIC PEPTIDOGLYCAN TRANSGLYCOSYLASE; 1.
DR   PANTHER; PTHR30400; MONOFUNCTIONAL BIOSYNTHETIC PEPTIDOGLYCAN TRANSGLYCOSYLASE; 1.
DR   Pfam; PF00912; Transgly; 1.
DR   SUPFAM; SSF53955; Lysozyme-like; 1.
PE   4: Predicted;
KW   Cell inner membrane {ECO:0000256|ARBA:ARBA00022519};
KW   Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW   Cell shape {ECO:0000256|ARBA:ARBA00022960};
KW   Cell wall biogenesis/degradation {ECO:0000256|ARBA:ARBA00023316};
KW   Glycosyltransferase {ECO:0000256|ARBA:ARBA00022676};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136};
KW   Peptidoglycan synthesis {ECO:0000256|ARBA:ARBA00022984};
KW   Reference proteome {ECO:0000313|Proteomes:UP000033054};
KW   Transferase {ECO:0000256|ARBA:ARBA00022679};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989}.
FT   DOMAIN          445..600
FT                   /note="Glycosyl transferase family 51"
FT                   /evidence="ECO:0000259|Pfam:PF00912"
FT   REGION          694..757
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        694..709
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        730..751
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   757 AA;  84944 MW;  778B33A68AC35085 CRC64;
     MTYRQRKAIR IAGWVFLSIF LLALVGAGVA YSKRESLLKT ALERGIRKAK RDYNLDVRIG
     SAKFTGLSSL AFTDISVVPN KRDSLARIQR VELEVRFWPL LAGKIGLSGM TLENGLIQVI
     KRDSLSNIDF LLHRKRDSTA TDSAPVEPTR RTNLADVTEN LIDNILSKIP DDLNVNNLEF
     RGIDIGNDTI NLLTQTAVIK NENVTSTIKL NGNQAIWHLA GTADPGDREY NLALYAEGKN
     GRPQPIDIPY VQKKYNLKVQ ADTLRAELRD VDRSGGQFRL EGAGSVRNLR INHPAIARTD
     VLVSSAAVDA NLFVGENYVG IDSSSTLHLG EVSARPFIKY TLPDAGSSTG QGKLYDVQLH
     TDPMDAQALF NSFPQGLFES LEGMQVSGKL KYDLSFQFDT ALPDSVKFNS GLTQDNFRVI
     KMGRTDFAAI NKPFVYTPYE KGKPVRDIIV GPENPDYTPI DQISPDLRNA LLTSEDYNFF
     THNGFNEKAF RVSIATNFKE KSFKRGASTI SMQLVKNAFL SRNKTLSRKI EEILIVWLIE
     NEHIVSKERM YEVYLNIIEW GRNIYGIGEA ARYYFAKSPA DLNLGESIFL AFVVPRPKAA
     LNWFIPDGTL QTRNVRGYFK LIGRIMARRG LTAPDSGAYG FYDVRLRPGL RKEVAPVDSL
     FQGDSLMTDP VDTEIDADEE GGNGIGNFFR RLFKGKKTDD NRNTDEQPTV QPDRQEALPG
     IPAPADTVKT RKQLRQEKRE RKRREKEARQ ALENSNQ
//