ID A0A0E4CV98_9BACL Unreviewed; 649 AA.
AC A0A0E4CV98;
DT 24-JUN-2015, integrated into UniProtKB/TrEMBL.
DT 24-JUN-2015, sequence version 1.
DT 27-MAR-2024, entry version 39.
DE SubName: Full=Radical SAM domain protein {ECO:0000313|EMBL:CQR53824.1};
GN ORFNames=PRIO_1565 {ECO:0000313|EMBL:CQR53824.1};
OS Paenibacillus riograndensis SBR5.
OC Bacteria; Bacillota; Bacilli; Bacillales; Paenibacillaceae; Paenibacillus;
OC Paenibacillus sonchi group.
OX NCBI_TaxID=1073571 {ECO:0000313|EMBL:CQR53824.1, ECO:0000313|Proteomes:UP000033163};
RN [1] {ECO:0000313|Proteomes:UP000033163}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Wibberg D.;
RL Submitted (MAR-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=[4Fe-4S] cluster; Xref=ChEBI:CHEBI:49883;
CC Evidence={ECO:0000256|ARBA:ARBA00001966};
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DR EMBL; LN831776; CQR53824.1; -; Genomic_DNA.
DR RefSeq; WP_046501766.1; NZ_LN831776.1.
DR AlphaFoldDB; A0A0E4CV98; -.
DR STRING; 483937.AMQ84_04575; -.
DR KEGG; pri:PRIO_1565; -.
DR PATRIC; fig|1073571.4.peg.1634; -.
DR HOGENOM; CLU_021572_1_0_9; -.
DR Proteomes; UP000033163; Chromosome I.
DR GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR GO; GO:0031419; F:cobalamin binding; IEA:InterPro.
DR GO; GO:0051536; F:iron-sulfur cluster binding; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR CDD; cd01335; Radical_SAM; 1.
DR CDD; cd02068; radical_SAM_B12_BD; 1.
DR Gene3D; 3.40.50.280; Cobalamin-binding domain; 1.
DR Gene3D; 3.80.30.20; tm_1862 like domain; 1.
DR InterPro; IPR006158; Cobalamin-bd.
DR InterPro; IPR036724; Cobalamin-bd_sf.
DR InterPro; IPR025288; DUF4080.
DR InterPro; IPR006638; Elp3/MiaA/NifB-like_rSAM.
DR InterPro; IPR034466; Methyltransferase_Class_B.
DR InterPro; IPR007197; rSAM.
DR InterPro; IPR023404; rSAM_horseshoe.
DR PANTHER; PTHR43409; ANAEROBIC MAGNESIUM-PROTOPORPHYRIN IX MONOMETHYL ESTER CYCLASE-RELATED; 1.
DR PANTHER; PTHR43409:SF18; RADICAL SAM SUPERFAMILY PROTEIN; 1.
DR Pfam; PF02310; B12-binding; 1.
DR Pfam; PF13311; DUF4080; 1.
DR Pfam; PF04055; Radical_SAM; 1.
DR SFLD; SFLDG01082; B12-binding_domain_containing; 1.
DR SFLD; SFLDG01123; methyltransferase_(Class_B); 1.
DR SMART; SM00729; Elp3; 1.
DR SUPFAM; SSF52242; Cobalamin (vitamin B12)-binding domain; 1.
DR SUPFAM; SSF102114; Radical SAM enzymes; 1.
DR PROSITE; PS51332; B12_BINDING; 1.
DR PROSITE; PS51918; RADICAL_SAM; 1.
PE 4: Predicted;
KW 4Fe-4S {ECO:0000256|ARBA:ARBA00022485};
KW Iron {ECO:0000256|ARBA:ARBA00022485};
KW Iron-sulfur {ECO:0000256|ARBA:ARBA00022485};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723}.
FT DOMAIN 1..134
FT /note="B12-binding"
FT /evidence="ECO:0000259|PROSITE:PS51332"
FT DOMAIN 173..412
FT /note="Radical SAM core"
FT /evidence="ECO:0000259|PROSITE:PS51918"
FT REGION 574..593
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 649 AA; 74259 MW; 17B07D72B748463A CRC64;
MKIILATLNA KYIHTSLAIR LLKAYSEHEF QDIHLAEYTI KDPVMNIVSD LFQKKPDVIG
FSCYIWNIEE TVKVIGILKQ VMPEVTVVLG GPEVSYEPLY WMQREAGIDF VVNGDGEETF
HHLLQELRDD RKFHFVYGAA YRKGEELIVN PPRPKSDLNT LPSPHRFPDD LPDLGKRIVY
FETSRGCPFN CQFCLSSIEV GVRYYDIERV KADLLYLIEN GAKVIKFLDR TFNINRNYAM
EMFQFLIDNH QGCVFQFEIT ADIMRPEVLD FLAEHAPPGI FRFEIGVQST NDETNELVKR
RQNFTKLSRT VMKIKASGNI DQHLDLIAGL PQEDYATFRK TFNDVFAMEP EELQLGFLKM
LRGTGLRAQA AKYNYTYMEH APYEILSSHV MPFSDIIRLK RLEDVLEKYW NSHRLDHSVK
YLIRHVFQSP FDFFQEFGDY WEARGWQKIG HQLEDLFTRL HAFLTDRRTP SMPVITGLMK
LDYFLGHKYK PRKIWWDITL DKPEWSHYMK EIAEHPERLS AKLADAGFSE RELQKFTVLE
VLPFRLEAVL DSISGLRFDP AAVAVAEAAD NADRIPDSLS PAGGGEAGTA AAKRGAANPA
ASAAAPLAAA DKRSTALAEA LPDAGGSTLL IVMYQQDESQ RAQYYALPL
//
