ID   A0A0E4CY75_9BACL        Unreviewed;      1106 AA.
AC   A0A0E4CY75;
DT   24-JUN-2015, integrated into UniProtKB/TrEMBL.
DT   24-JUN-2015, sequence version 1.
DT   27-MAR-2024, entry version 36.
DE   SubName: Full=Alpha-D-mannosidase {ECO:0000313|EMBL:CQR57199.1};
DE            EC=3.2.1.24 {ECO:0000313|EMBL:CQR57199.1};
GN   ORFNames=PRIO_4797 {ECO:0000313|EMBL:CQR57199.1};
OS   Paenibacillus riograndensis SBR5.
OC   Bacteria; Bacillota; Bacilli; Bacillales; Paenibacillaceae; Paenibacillus;
OC   Paenibacillus sonchi group.
OX   NCBI_TaxID=1073571 {ECO:0000313|EMBL:CQR57199.1, ECO:0000313|Proteomes:UP000033163};
RN   [1] {ECO:0000313|Proteomes:UP000033163}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Wibberg D.;
RL   Submitted (MAR-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the glycosyl hydrolase 38 family.
CC       {ECO:0000256|ARBA:ARBA00009792}.
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DR   EMBL; LN831776; CQR57199.1; -; Genomic_DNA.
DR   RefSeq; WP_046504955.1; NZ_LN831776.1.
DR   AlphaFoldDB; A0A0E4CY75; -.
DR   STRING; 483937.AMQ84_02670; -.
DR   KEGG; pri:PRIO_4797; -.
DR   PATRIC; fig|1073571.4.peg.5155; -.
DR   HOGENOM; CLU_003442_0_1_9; -.
DR   Proteomes; UP000033163; Chromosome I.
DR   GO; GO:0004559; F:alpha-mannosidase activity; IEA:UniProtKB-EC.
DR   GO; GO:0030246; F:carbohydrate binding; IEA:InterPro.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006013; P:mannose metabolic process; IEA:InterPro.
DR   CDD; cd10789; GH38N_AMII_ER_cytosolic; 1.
DR   Gene3D; 2.60.40.2220; -; 1.
DR   Gene3D; 3.20.110.10; Glycoside hydrolase 38, N terminal domain; 1.
DR   Gene3D; 1.20.1270.50; Glycoside hydrolase family 38, central domain; 1.
DR   InterPro; IPR011013; Gal_mutarotase_sf_dom.
DR   InterPro; IPR041147; GH38_C.
DR   InterPro; IPR011330; Glyco_hydro/deAcase_b/a-brl.
DR   InterPro; IPR011682; Glyco_hydro_38_C.
DR   InterPro; IPR015341; Glyco_hydro_38_cen.
DR   InterPro; IPR037094; Glyco_hydro_38_cen_sf.
DR   InterPro; IPR000602; Glyco_hydro_38_N.
DR   InterPro; IPR027291; Glyco_hydro_38_N_sf.
DR   InterPro; IPR028995; Glyco_hydro_57/38_cen_sf.
DR   PANTHER; PTHR46017; ALPHA-MANNOSIDASE 2C1; 1.
DR   PANTHER; PTHR46017:SF1; ALPHA-MANNOSIDASE 2C1; 1.
DR   Pfam; PF09261; Alpha-mann_mid; 1.
DR   Pfam; PF17677; Glyco_hydro38C2; 1.
DR   Pfam; PF07748; Glyco_hydro_38C; 1.
DR   Pfam; PF01074; Glyco_hydro_38N; 1.
DR   SMART; SM00872; Alpha-mann_mid; 1.
DR   SUPFAM; SSF88688; Families 57/38 glycoside transferase middle domain; 1.
DR   SUPFAM; SSF74650; Galactose mutarotase-like; 1.
DR   SUPFAM; SSF88713; Glycoside hydrolase/deacetylase; 1.
PE   3: Inferred from homology;
KW   Glycosidase {ECO:0000256|ARBA:ARBA00023295, ECO:0000313|EMBL:CQR57199.1};
KW   Hydrolase {ECO:0000313|EMBL:CQR57199.1};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723}.
FT   DOMAIN          518..598
FT                   /note="Glycoside hydrolase family 38 central"
FT                   /evidence="ECO:0000259|SMART:SM00872"
SQ   SEQUENCE   1106 AA;  125705 MW;  2F5C68A32F6336C4 CRC64;
     MFWTEEKLGA RLRELEGYRY RDVVKLSDWL AVEDKDGANG KYPPQLEGDT RLQLGDYWTG
     RDAYLWLHST IEVPAEWKGK RVVGLFDFGR TGGGNNSGFE SLLYLDGKPY QGVDSNHQEV
     FLEEDAAGRA LDFTFRLWSG LEGGGRPVPQ EHRIMRSELA WLDEAADNLY YTGRAALSTC
     KQLADQQPEK QELLMALNRA FNKLDWSKPG SAGFYRSVRE AESLLLEQLA LLEAKPPVTV
     TAIGHTHIDV AWLWRLTHTR EKAARSFSTV LRLMKQYPEY IFLQTQPQLY AYIKEDYPEI
     YAEIRKRVEE GRWEAGGAMW LEADCNLTSG ESLVRQILYG TKFFREEFGV DCKYLWLPDV
     FGYSWALPQI LRKSGIDTFM TTKISWSQYN RMPHDTFRWR GIDGSEVLTH FITTPEGPDS
     GAWYYTYNGL IEAFSVQGIW DQYRDKNLNR ELLLSYGYGD GGGGVNREML EMRRRLDKMP
     GIPAVRTGRA DEYFERLNEA VRSTDQYVHT WDGELYLEFH RGTYTSQAYN KRMNRKLELL
     YREAEWLQVL LAVEKGSFSS YPAQLLLEGW HTILRNQFHD IIPGSSIREV YEDSRLEYAE
     AERIGSTAAE AAAAGLVEGL VEERAEELAE GLAEEQAEEM TEGLAEELAE GAGFRQETEY
     TVFNGAFYER TELAAIPYEA AGEDMVWTTA AGRQLSSQRV GGEWLIEVPA VPMLGSTVIK
     AGTVAAFAVE ADSAGSADSA AGKIEAREGN ALTPGDPVPF EWEDSRLTTP FYVLEWNDAG
     QLSRIYDRRE QREVLAPGEN GNVLQVFEDK PKMYDAWDID LFYQEKKREI TDLRSVKLTE
     CGALAAVLEF TWQYMDSSIV QKVKVYSRSA RIDFETLADW HEQHQLLKTA FPVAVRATEA
     TYDIQFGNVK RPTHWNTSWD YARFESVGHQ WADLSERGYG VSLLNDCKYG YDIKDHVMRL
     SLIKSATEPD WQADQGEHRF TYALLPHKGD WVAANTVQEA WSLNNPLRVV KGGYSAGAGR
     SLIKTDCGSI AVDALKMAEN GEGFIVRLHE YTGTRSTVTF SSDYPVHSWQ ECDLMERPVG
     EIKPGGAVTC EIKPYEISTF IVRFSG
//