ID A0A0E8E7E4_BORPT Unreviewed; 337 AA.
AC A0A0E8E7E4;
DT 24-JUN-2015, integrated into UniProtKB/TrEMBL.
DT 24-JUN-2015, sequence version 1.
DT 27-MAR-2024, entry version 49.
DE SubName: Full=Acetylpolyamine aminohydrolase {ECO:0000313|EMBL:SUV64964.1};
GN Name=aphA_1 {ECO:0000313|EMBL:SUV64964.1};
GN ORFNames=NCTC10911_02002 {ECO:0000313|EMBL:SUV64964.1};
OS Bordetella pertussis.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Alcaligenaceae; Bordetella.
OX NCBI_TaxID=520 {ECO:0000313|EMBL:SUV64964.1, ECO:0000313|Proteomes:UP000255014};
RN [1] {ECO:0000313|EMBL:SUV64964.1, ECO:0000313|Proteomes:UP000255014}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NCTC10911 {ECO:0000313|EMBL:SUV64964.1,
RC ECO:0000313|Proteomes:UP000255014};
RG Pathogen Informatics;
RA Doyle S.;
RL Submitted (JUN-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC Evidence={ECO:0000256|ARBA:ARBA00001947};
CC -!- SIMILARITY: Belongs to the histone deacetylase family.
CC {ECO:0000256|ARBA:ARBA00005947}.
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DR EMBL; UFTT01000002; SUV64964.1; -; Genomic_DNA.
DR RefSeq; WP_047122810.1; NZ_UIGD01000003.1.
DR AlphaFoldDB; A0A0E8E7E4; -.
DR GeneID; 69602197; -.
DR Proteomes; UP000255014; Unassembled WGS sequence.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR CDD; cd10001; HDAC_classII_APAH; 1.
DR Gene3D; 3.40.800.20; Histone deacetylase domain; 1.
DR InterPro; IPR000286; His_deacetylse.
DR InterPro; IPR023801; His_deacetylse_dom.
DR InterPro; IPR037138; His_deacetylse_dom_sf.
DR InterPro; IPR023696; Ureohydrolase_dom_sf.
DR PANTHER; PTHR10625:SF9; HISTONE DEACETYLASE 8; 1.
DR PANTHER; PTHR10625; HISTONE DEACETYLASE HDAC1-RELATED; 1.
DR Pfam; PF00850; Hist_deacetyl; 1.
DR PRINTS; PR01270; HDASUPER.
DR SUPFAM; SSF52768; Arginase/deacetylase; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000313|EMBL:SUV64964.1}.
FT DOMAIN 13..331
FT /note="Histone deacetylase"
FT /evidence="ECO:0000259|Pfam:PF00850"
SQ SEQUENCE 337 AA; 36882 MW; A38FF475625C70AF CRC64;
MRLGRISAPT DVPARAETLR AMLASRGVTV DSPPDYGREP LEGIHSHEYL DYLEHAYTRW
QAMRANGADP GPEVLPNLSP YYNGRVEHAA RGPCPSTSIV AETGYYLSDL SCPVGPHTWR
SALRSTHCAV AAADWALQNQ ALAYALCRPS RHHAHRDRAG GFCYLNSSAA AAQRLAQRCE
RVVVLDVDAH HGDGTQNIFY QRSDVMTISL HADPSGYYPF YTGYAHERGY GSGHGYNLNF
PLPHGARNAI FLETLDSALT ALRDYRPRAL VLALGFDTYK DDPISVLKLD MDAYRQIGER
INGLGLPTVV VQEGGYMVPA IGPALEAFLQ GMAPATV
//
