ID   A0A0E9MNC8_9SPHN        Unreviewed;       661 AA.
AC   A0A0E9MNC8;
DT   24-JUN-2015, integrated into UniProtKB/TrEMBL.
DT   24-JUN-2015, sequence version 1.
DT   27-MAR-2024, entry version 21.
DE   SubName: Full=Putative penicillin-binding protein {ECO:0000313|EMBL:GAO39003.1};
GN   ORFNames=SCH01S_23_00460 {ECO:0000313|EMBL:GAO39003.1};
OS   Sphingomonas changbaiensis NBRC 104936.
OC   Bacteria; Pseudomonadota; Alphaproteobacteria; Sphingomonadales;
OC   Sphingomonadaceae; Sphingomonas.
OX   NCBI_TaxID=1219043 {ECO:0000313|EMBL:GAO39003.1, ECO:0000313|Proteomes:UP000033202};
RN   [1] {ECO:0000313|EMBL:GAO39003.1, ECO:0000313|Proteomes:UP000033202}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NBRC 104936 {ECO:0000313|EMBL:GAO39003.1,
RC   ECO:0000313|Proteomes:UP000033202};
RA   Katano-Makiyama Y., Hosoyama A., Hashimoto M., Noguchi M., Tsuchikane K.,
RA   Ohji S., Yamazoe A., Ichikawa N., Kimura A., Fujita N.;
RT   "Whole genome shotgun sequence of Sphingomonas changbaiensis NBRC 104936.";
RL   Submitted (APR-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004167}; Single-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004167}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:GAO39003.1}.
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DR   EMBL; BBWU01000023; GAO39003.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A0E9MNC8; -.
DR   STRING; 1219043.SCH01S_23_00460; -.
DR   OrthoDB; 9766847at2; -.
DR   Proteomes; UP000033202; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0008658; F:penicillin binding; IEA:InterPro.
DR   GO; GO:0009002; F:serine-type D-Ala-D-Ala carboxypeptidase activity; IEA:InterPro.
DR   GO; GO:0009252; P:peptidoglycan biosynthetic process; IEA:InterPro.
DR   Gene3D; 3.40.710.10; DD-peptidase/beta-lactamase superfamily; 1.
DR   Gene3D; 3.90.1310.10; Penicillin-binding protein 2a (Domain 2); 1.
DR   InterPro; IPR012338; Beta-lactam/transpept-like.
DR   InterPro; IPR005311; PBP_dimer.
DR   InterPro; IPR036138; PBP_dimer_sf.
DR   InterPro; IPR001460; PCN-bd_Tpept.
DR   InterPro; IPR017790; Penicillin-binding_protein_2.
DR   NCBIfam; TIGR03423; pbp2_mrdA; 1.
DR   PANTHER; PTHR30627; PEPTIDOGLYCAN D,D-TRANSPEPTIDASE; 1.
DR   PANTHER; PTHR30627:SF2; PEPTIDOGLYCAN D,D-TRANSPEPTIDASE MRDA; 1.
DR   Pfam; PF03717; PBP_dimer; 1.
DR   Pfam; PF00905; Transpeptidase; 1.
DR   SUPFAM; SSF56601; beta-lactamase/transpeptidase-like; 1.
DR   SUPFAM; SSF56519; Penicillin binding protein dimerisation domain; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000033202};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        21..41
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          64..236
FT                   /note="Penicillin-binding protein dimerisation"
FT                   /evidence="ECO:0000259|Pfam:PF03717"
FT   DOMAIN          268..581
FT                   /note="Penicillin-binding protein transpeptidase"
FT                   /evidence="ECO:0000259|Pfam:PF00905"
FT   REGION          639..661
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   661 AA;  71582 MW;  B68CC6BD7F991C68 CRC64;
     MKRPKKIVTE ASQSFTFTRR ALLLGGLQGG VGAVLAGRLA WLSIAENEHY ALLSESNRVN
     LTLIPPRRGW IVDRQGKPIA INRTDFRVDL IPDRIVDKDK LLGDLQALLQ LPEEEMQRIR
     DDLEEAQGFK PVQVAEDLDW EKYAAVSVRL NDLPGVSPMR GYSRFYPDGA AVGHLVGYVG
     AASAKDYEES KDPLLITPGF KVGKDGLEKV MEPTLRGTPG AKRVEVTARG KLVKELTTRS
     DVPGHTLKLS IDAGLQTYAA RRLGTNSGSV VVIDLATGGL LAFVSMPSYD PNSFSDGIGR
     DEWKMLSEDD HIPLMNKAVL GLYPPGSTVK PMNALALLEA GVDPRDRVVC AGALRVGNGL
     FHCHKKRGHG PLDMKNAVMQ SCDIYFYEMS RRLGYDRIAP VAKAMGLGQK FDLPLVSQRY
     GTVPDSAWKL KKYHQPWTIP DSLNASIGQG YVLANPLQMA VMASRLASGR EIKPSMFFGH
     DKPAAPLPYS AEHFAIVRDA MYGVVNEGGT GGAARMQVPG VALAAKTGTA QVRRITMAER
     AGGVLSNASL PFRMRDHAHF ICFAPADNPR YAASVVLEHG GHTVRNLDSP MTGRDIMTYL
     FDPDRAMKSL AEVEPTWGGD IATRMAAKAE AWKLAKAGAT PLPTSTPTPA DPGANVAAAV
     D
//