ID A0A0E9N2W1_9BACT Unreviewed; 1582 AA.
AC A0A0E9N2W1;
DT 24-JUN-2015, integrated into UniProtKB/TrEMBL.
DT 24-JUN-2015, sequence version 1.
DT 27-MAR-2024, entry version 38.
DE SubName: Full=ATP-dependent DNA helicase {ECO:0000313|EMBL:GAO44123.1};
GN ORFNames=FPE01S_03_01620 {ECO:0000313|EMBL:GAO44123.1};
OS Flavihumibacter petaseus NBRC 106054.
OC Bacteria; Bacteroidota; Chitinophagia; Chitinophagales; Chitinophagaceae;
OC Flavihumibacter.
OX NCBI_TaxID=1220578 {ECO:0000313|EMBL:GAO44123.1, ECO:0000313|Proteomes:UP000033121};
RN [1] {ECO:0000313|EMBL:GAO44123.1, ECO:0000313|Proteomes:UP000033121}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NBRC 106054 {ECO:0000313|EMBL:GAO44123.1,
RC ECO:0000313|Proteomes:UP000033121};
RA Miyazawa S., Hosoyama A., Hashimoto M., Noguchi M., Tsuchikane K., Ohji S.,
RA Yamazoe A., Ichikawa N., Kimura A., Fujita N.;
RT "Whole genome shotgun sequence of Flavihumibacter petaseus NBRC 106054.";
RL Submitted (APR-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=3.6.4.12;
CC Evidence={ECO:0000256|ARBA:ARBA00001665};
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=5.6.2.4;
CC Evidence={ECO:0000256|ARBA:ARBA00034618};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:GAO44123.1}.
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DR EMBL; BBWV01000003; GAO44123.1; -; Genomic_DNA.
DR RefSeq; WP_046370097.1; NZ_BBWV01000003.1.
DR STRING; 1220578.FPE01S_03_01620; -.
DR OrthoDB; 9763310at2; -.
DR Proteomes; UP000033121; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0004386; F:helicase activity; IEA:UniProtKB-UniRule.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-UniRule.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0006310; P:DNA recombination; IEA:InterPro.
DR CDD; cd17920; DEXHc_RecQ; 1.
DR CDD; cd17932; DEXQc_UvrD; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 6.
DR Gene3D; 3.30.420.10; Ribonuclease H-like superfamily/Ribonuclease H; 1.
DR InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR InterPro; IPR002464; DNA/RNA_helicase_DEAH_CS.
DR InterPro; IPR004589; DNA_helicase_ATP-dep_RecQ.
DR InterPro; IPR014017; DNA_helicase_UvrD-like_C.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR012337; RNaseH-like_sf.
DR InterPro; IPR036397; RNaseH_sf.
DR InterPro; IPR014016; UvrD-like_ATP-bd.
DR NCBIfam; TIGR00614; recQ_fam; 1.
DR PANTHER; PTHR13710; DNA HELICASE RECQ FAMILY MEMBER; 1.
DR Pfam; PF00270; DEAD; 1.
DR Pfam; PF00271; Helicase_C; 1.
DR Pfam; PF00580; UvrD-helicase; 2.
DR Pfam; PF13361; UvrD_C; 2.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM00490; HELICc; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR SUPFAM; SSF53098; Ribonuclease H-like; 1.
DR PROSITE; PS00690; DEAH_ATP_HELICASE; 1.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
DR PROSITE; PS51198; UVRD_HELICASE_ATP_BIND; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW ProRule:PRU00560};
KW Helicase {ECO:0000256|ARBA:ARBA00022806, ECO:0000256|PROSITE-
KW ProRule:PRU00560};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|PROSITE-
KW ProRule:PRU00560};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW ProRule:PRU00560}; Reference proteome {ECO:0000313|Proteomes:UP000033121}.
FT DOMAIN 271..451
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 464..628
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
FT DOMAIN 1030..1361
FT /note="UvrD-like helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51198"
FT BINDING 1051..1058
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00560"
SQ SEQUENCE 1582 AA; 179333 MW; F4F2D8077B787105 CRC64;
MPAIAFFDLE VDPKSRKVVD CGFVTDNGLQ YRGASPGKFF DGLNACSFIA GHNVFAHDLP
VLQRRFQDVD WNKWKVIDTL LLSPLLFPSR PYHRLVKDDK IADDAPNNPL ADSIKARDLF
LEEVAAFRQL PSELKAIFFR LLSTDVKYAD FFRYLEFSDA QQLPTVHLIK NCFGQEICTQ
APLAEMVWKQ PIELAYALAL IRAQDKYSIL PKWLTRSFPA IETVIKILRG TPCGHCPYCA
ASFDAHEALR RFFGYDSFRN YEGKTLQLSA VNAAINNQSL LAIFPTGGGK SITFQVPALI
SAEAEKGLTI VISPLQSLMK DQVDNLLLKQ ITAAETINGL LNPIERAKAL ERVEDGSAGI
LYIAPEMLRS ATIERILLGR TISRFVIDEA HCFSSWGHDF RVDYLYIGEF IKNLQQKKQL
PAPIPVSCFS ATAKPQVIDD IRQYFKDRLG LDLQLFQASV RRRNLHYKVI EVESEEAKYD
RLRNLVAAKD CPTIIYVSRT KKAEELAARL TQDGFAAMPF HGKMESQEKT RNQNAFLGGD
TRIMVATSAF GMGVDKKDVG LVIHYDIADS LENYVQEAGR AGRDENIEAD CFVLFNPEDI
DKHFIRLNQT RMTQVEINQI WKAVKDLTKK KMTVSHSALE IARKAGWDEQ VRDIETRVTT
AIAALENADY VKRKQNLPQV FATSIEVGNV DEAVRRINES DRIPAAQKEN AVRLAKSLVS
SSRKITNGEI NGARVDYLAD RLGITVYEAI DLVNLLREER VVADAREIEL GIDKEELARA
SKLLHAHIQV ERLLLRNLSL QSRSYNIKEL IAAMAAAAQK DVPMQQLLTI LNYWVVRKWC
KRHLLEHSRN HLQLHLSLDQ DTMEQQIERR SEICRFIVEK AVTASTVSII ELRDGFNSQH
SLYQWKATLP DIEDALLYLS RIGAARIEGG FMVTYNKIQL ERLKENAKLQ YKAEDYAPLA
RYYEQKVQQI HIVGEYARKM AQEDNAAAID FTEDYFSIPV DQFVRKYFPE EKAKALKRNV
SNEKFERIFG ALDKQQRAII DAGHQHIVVA AGPGSGKTRV LVHKMASLVM MEDIKQEQLL
MLTFSRSAAM EFKKRLLELI GNAAHYIDIK TFHSFCFDLL GKQGNLEKSK EIIQLALEKI
RSGEIEPGRI TKQVLVIDEA QDVDDEEFAL IRLLLDHNEN MRTLVVGDDD QNIFAFRGAN
NHFMRAMCDE PVARIFNLLT NYRSAANLVD FSNQWISKLS GRLKLDAIQP HSNTPGEIDI
LQYAAKDIAS GAAARLPAAL GDGTTAILTR TNEEAYLVQA VLKQRGIPCR LIQGNEGFSL
YNLAELRSFS NFICDYAEGP TISSEAWENG LIMIRDNYKA STLLDTCNRL IHAFRAGNPP
TLYKSDWKSY LSEVSLADFV DRGEQAVHLS TMHKAKGREY DNVYLLLDDL DPNTDESKRL
LYVAMTRAKR RLSVHYNGTY FNHMPVADRS DRFIPDALES PSVIQLQLTH KDVHLGYFEY
VEHRTRQIVS GQQLTILPDG ALAYRGEAVL KFSSAFKSTL EGWYQKGYQL AAAEVTFVLH
WTNVDTGKST RIILPLVQLK KR
//
