ID A0A0E9NBE0_SAICN Unreviewed; 1130 AA.
AC A0A0E9NBE0;
DT 24-JUN-2015, integrated into UniProtKB/TrEMBL.
DT 24-JUN-2015, sequence version 1.
DT 03-MAY-2023, entry version 36.
DE RecName: Full=ADP-ribosylation factor GTPase-activating protein {ECO:0000256|RuleBase:RU369028};
GN ORFNames=G7K_1334-t1 {ECO:0000313|EMBL:GAO47123.1};
OS Saitoella complicata (strain BCRC 22490 / CBS 7301 / JCM 7358 / NBRC 10748
OS / NRRL Y-17804).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC Taphrinomycotina incertae sedis; Saitoella.
OX NCBI_TaxID=698492 {ECO:0000313|EMBL:GAO47123.1, ECO:0000313|Proteomes:UP000033140};
RN [1] {ECO:0000313|EMBL:GAO47123.1, ECO:0000313|Proteomes:UP000033140}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NRRL Y-17804 {ECO:0000313|EMBL:GAO47123.1,
RC ECO:0000313|Proteomes:UP000033140};
RX PubMed=21914972; DOI=10.2323/jgam.57.243;
RA Nishida H., Hamamoto M., Sugiyama J.;
RT "Draft genome sequencing of the enigmatic yeast Saitoella complicata.";
RL J. Gen. Appl. Microbiol. 57:243-246(2011).
RN [2] {ECO:0000313|EMBL:GAO47123.1, ECO:0000313|Proteomes:UP000033140}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NRRL Y-17804 {ECO:0000313|EMBL:GAO47123.1,
RC ECO:0000313|Proteomes:UP000033140};
RX PubMed=24646756; DOI=10.2323/jgam.60.7;
RA Nishida H., Matsumoto T., Kondo S., Hamamoto M., Yoshikawa H.;
RT "The early diverging ascomycetous budding yeast Saitoella complicata has
RT three histone deacetylases belonging to the Clr6, Hos2, and Rpd3
RT lineages.";
RL J. Gen. Appl. Microbiol. 60:7-12(2014).
CC -!- FUNCTION: GTPase-activating protein for the ADP ribosylation factor
CC family. {ECO:0000256|RuleBase:RU369028}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|RuleBase:RU369028}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:GAO47123.1}.
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DR EMBL; BACD03000007; GAO47123.1; -; Genomic_DNA.
DR RefSeq; XP_019026402.1; XM_019170466.1.
DR AlphaFoldDB; A0A0E9NBE0; -.
DR STRING; 698492.A0A0E9NBE0; -.
DR GeneID; 30187313; -.
DR OMA; FSFWVHN; -.
DR OrthoDB; 1449795at2759; -.
DR Proteomes; UP000033140; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR CDD; cd08204; ArfGap; 1.
DR CDD; cd07608; BAR_ArfGAP_fungi; 1.
DR Gene3D; 1.10.220.150; Arf GTPase activating protein; 1.
DR Gene3D; 1.20.1270.60; Arfaptin homology (AH) domain/BAR domain; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR InterPro; IPR045258; ACAP1/2/3-like.
DR InterPro; IPR027267; AH/BAR_dom_sf.
DR InterPro; IPR037278; ARFGAP/RecO.
DR InterPro; IPR001164; ArfGAP_dom.
DR InterPro; IPR038508; ArfGAP_dom_sf.
DR InterPro; IPR004148; BAR_dom.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR001849; PH_domain.
DR PANTHER; PTHR23180:SF160; ADP-RIBOSYLATION FACTOR GTPASE-ACTIVATING PROTEIN EFFECTOR PROTEIN 1; 1.
DR PANTHER; PTHR23180; CENTAURIN/ARF; 1.
DR Pfam; PF01412; ArfGap; 1.
DR Pfam; PF16746; BAR_3; 1.
DR Pfam; PF00169; PH; 1.
DR SMART; SM00105; ArfGap; 1.
DR SMART; SM00233; PH; 1.
DR SUPFAM; SSF57863; ArfGap/RecO-like zinc finger; 1.
DR SUPFAM; SSF103657; BAR/IMD domain-like; 1.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR PROSITE; PS50115; ARFGAP; 1.
DR PROSITE; PS50003; PH_DOMAIN; 1.
PE 4: Predicted;
KW ANK repeat {ECO:0000256|RuleBase:RU369028};
KW Cytoplasm {ECO:0000256|RuleBase:RU369028};
KW GTPase activation {ECO:0000256|RuleBase:RU369028};
KW Metal-binding {ECO:0000256|RuleBase:RU369028};
KW Reference proteome {ECO:0000313|Proteomes:UP000033140};
KW Repeat {ECO:0000256|RuleBase:RU369028};
KW Zinc {ECO:0000256|RuleBase:RU369028};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00288}.
FT DOMAIN 635..740
FT /note="PH"
FT /evidence="ECO:0000259|PROSITE:PS50003"
FT DOMAIN 817..950
FT /note="Arf-GAP"
FT /evidence="ECO:0000259|PROSITE:PS50115"
FT REGION 773..802
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1055..1086
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 773..798
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1055..1074
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1130 AA; 125298 MW; 56608B5B83ACC7A5 CRC64;
MGAVSSRSED APALYLRDSA TIALKSITVS KGDAPRETMF TITPNVESTF VSARSHGDAL
IEFVQDPDTA FQTQLAPLLL KVPYDDDLRL TFNFVLRRPL GKERDTCVEG LTFMNAPHRQ
ELESLLTKEF VMDSNLQKHP NARLVAQSLS TDGMEEKEIQ WSWDWNPPGE EDERHRGWRN
TCCFVEYDKT ADTFAIIASF AFWVSNTSPV LTTFMPPLHF PIPLLPNSND PMSVPSSPVM
GKQHVPPRLH IQTTSFTSEG SETKVGSDSP EMRTPVAERE MTVFGSPPTS TQMNMPSLST
VPTNTTAIAN SNTEPEDGPL FRATISSMEK QTVELKQKIK KVMKRAQEAV DAHRVATKAD
ERFVEALQVA ATSSTSLKPL LDVYMEPAYR ELRYFAENNA YQLQHRIIEP LRRQYDADIK
TMETKKRDFE DESKEYYGFL SRYLSQKSDA KEKKQMQSDT KYQKKRKDFE LHRFDYYSYM
QDIHGGRKEA EIVENVTEYA WNQFEHVQQT ARTIGELRGA LEMCRSAVQQ SKKDFRVLRT
EREERRRQLE TGEVPAEKSE KEAAYDTYSV VGSVAGSTAP LLGQHGQYSS SESEGVPIPT
VTNTTAAMLS PSPPSMSKPQ FKSLPETEFN AIDAARRKEG LLWALSRPAG HTDPKVVPKM
NWHKYWVVLA GGQLCEYSNW KQQPELHNAI NLRMATVREA RSADRRFCFE VITPQFKRVY
QATSQEDMQS WISVISNAIG SVLEGSSSIR HFEKTKFRGS IDTGLGVNVG EVLRSSSKKS
PMPPQIRPSS SNRPPPQQTG YFDDPALKHA AEEAEALNLL KKVREADPTN TSCADCGSQN
KAEWVAINFG AVVCIECSGV HRSLGTHISK MRSLTLDTKA MTPDLVDLLV ALGNRKHNTI
WEATLAEMPG PIAAPKPSPS SAREVKVKFV QAKYVHRAYV RTTDTASANA LLLEAIQRRD
VFVAMSALAA GAEPNVKKPG TEMSAVLIAI LAAVPETALA EDKLATSAEA HEDYHGTYPI
AELLLQNGAE VPTLTHELVK KLPLSAKIYL AQKASRSGAP QTQSTPTRQP SVRQQPPVGL
GLMQGGGSTS SLANGLAAMN INNTNGVKGV NPALQRIPTG SGKMPRLASP
//
