ID A0A0E9NBG5_SAICN Unreviewed; 965 AA.
AC A0A0E9NBG5;
DT 24-JUN-2015, integrated into UniProtKB/TrEMBL.
DT 24-JUN-2015, sequence version 1.
DT 27-MAR-2024, entry version 35.
DE RecName: Full=DNA 3'-5' helicase {ECO:0000256|ARBA:ARBA00034808};
DE EC=5.6.2.4 {ECO:0000256|ARBA:ARBA00034808};
GN ORFNames=G7K_1249-t1 {ECO:0000313|EMBL:GAO47036.1};
OS Saitoella complicata (strain BCRC 22490 / CBS 7301 / JCM 7358 / NBRC 10748
OS / NRRL Y-17804).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC Taphrinomycotina incertae sedis; Saitoella.
OX NCBI_TaxID=698492 {ECO:0000313|EMBL:GAO47036.1, ECO:0000313|Proteomes:UP000033140};
RN [1] {ECO:0000313|EMBL:GAO47036.1, ECO:0000313|Proteomes:UP000033140}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NRRL Y-17804 {ECO:0000313|EMBL:GAO47036.1,
RC ECO:0000313|Proteomes:UP000033140};
RX PubMed=21914972; DOI=10.2323/jgam.57.243;
RA Nishida H., Hamamoto M., Sugiyama J.;
RT "Draft genome sequencing of the enigmatic yeast Saitoella complicata.";
RL J. Gen. Appl. Microbiol. 57:243-246(2011).
RN [2] {ECO:0000313|EMBL:GAO47036.1, ECO:0000313|Proteomes:UP000033140}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NRRL Y-17804 {ECO:0000313|EMBL:GAO47036.1,
RC ECO:0000313|Proteomes:UP000033140};
RX PubMed=24646756; DOI=10.2323/jgam.60.7;
RA Nishida H., Matsumoto T., Kondo S., Hamamoto M., Yoshikawa H.;
RT "The early diverging ascomycetous budding yeast Saitoella complicata has
RT three histone deacetylases belonging to the Clr6, Hos2, and Rpd3
RT lineages.";
RL J. Gen. Appl. Microbiol. 60:7-12(2014).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=5.6.2.4;
CC Evidence={ECO:0000256|ARBA:ARBA00034618};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:GAO47036.1}.
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DR EMBL; BACD03000007; GAO47036.1; -; Genomic_DNA.
DR RefSeq; XP_019026317.1; XM_019169074.1.
DR AlphaFoldDB; A0A0E9NBG5; -.
DR STRING; 698492.A0A0E9NBG5; -.
DR GeneID; 30185921; -.
DR OrthoDB; 1330984at2759; -.
DR Proteomes; UP000033140; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0003678; F:DNA helicase activity; IEA:InterPro.
DR GO; GO:0016787; F:hydrolase activity; IEA:InterPro.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR014017; DNA_helicase_UvrD-like_C.
DR InterPro; IPR000212; DNA_helicase_UvrD/REP.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR014016; UvrD-like_ATP-bd.
DR PANTHER; PTHR11070:SF30; F-BOX DNA HELICASE 1; 1.
DR PANTHER; PTHR11070; UVRD / RECB / PCRA DNA HELICASE FAMILY MEMBER; 1.
DR Pfam; PF00580; UvrD-helicase; 1.
DR Pfam; PF13361; UvrD_C; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Helicase {ECO:0000256|ARBA:ARBA00022806};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000033140}.
FT DOMAIN 274..544
FT /note="UvrD-like helicase ATP-binding"
FT /evidence="ECO:0000259|Pfam:PF00580"
FT DOMAIN 721..791
FT /note="UvrD-like helicase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF13361"
FT REGION 360..391
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 937..965
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 965 AA; 109214 MW; 7A70E68B5DE5DBC7 CRC64;
MTPFSSTSSL FAFPTELVQV ITSYVSFLDI ERSIDASPLL FSFWAIGGTD LWEARCRHLE
DVKRKYFEHA RRPLLCKWVG CDVYGVENFK VPRRFCELSL AALVDQVEAS LGYTWAESTM
AHVEAVLTAV KAMAGVKAPG SFRLPPIPTD VTTTILPVLR TKSRQITSNL AVILQSNEAA
LYTLIAATLL LLPGSEVQDY IEWVHAQTAS VLPVDVLRYL VSAMVYLLDL HNLSSVVRHK
SASPMSRMTH AALQNVDWRS KQSSSQPNGH GQWTEEQLAV INPERPLGNL TKVFAYAGSG
KTTTLVEFAK ARSADERILF VAFNRTVAEH ILTKLSRGTQ DSRTVNSLAH AAIVAQDPRA
RAKAYAATRS SSQSSQRQSS SKERPRELTQ SEVIRLLQIP DRAGGSGQMT GYGKAGRILK
CLNKFLASAD PTLTEEHLPY QDPEKTKSMD PGELFSYATK LWRLVSDMNE PDAPLNYAAQ
VKLWQLSGKG IWARNGELDF DYILWDEAQD ATECELDVLR RLKSKVVLVG DVHQLIYVWR
GAKSTWESLQ ASNIFRLSQS FRFGRNIANA SNLLLQLKGE TIPVKGTDIA DHVYRKFPGW
ATDAEQLDYV IHHTVIFRSN KELVEKVLRL ATLPAMPRVH INVEEYQSRN YLSIYRDAYH
LYHKRPHMVT HWKLKKFATW DQLESYVEEQ DDEVDMALLS LVAMVPTFEQ PGFLEAVDRA
QENCVTSPEE SDVILTTTHR AKGLEWPRVV VGDDYWDAFD KRYQIGTGLW QAENLNLLNV
ACTRAQRELI LNDTMLGLLV RRQGLHRFFF RALLMALPCP RCNMPSSRTI SYIPSASAMS
FELCLPAPTP YTIPLGVTEY LCCLDCASQA EYLPLKEYAT WCRQVLEKRT GATLRKSVTD
LDEQSPFLNI DLKTLEIAEK ENVEKEICIQ YFWYGPKEDN DEQKKPEEDS DDELMVLEGG
SWRRL
//
