ID A0A0F0C8E3_9CLOT Unreviewed; 375 AA.
AC A0A0F0C8E3;
DT 24-JUN-2015, integrated into UniProtKB/TrEMBL.
DT 24-JUN-2015, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE SubName: Full=Multidrug resistance protein MdtA {ECO:0000313|EMBL:KJJ70050.1};
GN Name=mdtA_2 {ECO:0000313|EMBL:KJJ70050.1};
GN ORFNames=CLFS41_33970 {ECO:0000313|EMBL:KJJ70050.1};
OS Clostridium sp. FS41.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Clostridiaceae;
OC Clostridium.
OX NCBI_TaxID=1609975 {ECO:0000313|EMBL:KJJ70050.1, ECO:0000313|Proteomes:UP000033604};
RN [1] {ECO:0000313|EMBL:KJJ70050.1, ECO:0000313|Proteomes:UP000033604}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=FS41 {ECO:0000313|EMBL:KJJ70050.1,
RC ECO:0000313|Proteomes:UP000033604};
RA Poehlein A., Daniel R.;
RT "Genome sequencing of Clostridium sp. FS41.";
RL Submitted (FEB-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the membrane fusion protein (MFP) (TC 8.A.1)
CC family. {ECO:0000256|ARBA:ARBA00009477}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KJJ70050.1}.
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DR EMBL; JYHN01000062; KJJ70050.1; -; Genomic_DNA.
DR RefSeq; WP_045093059.1; NZ_JYHN01000062.1.
DR AlphaFoldDB; A0A0F0C8E3; -.
DR PATRIC; fig|1609975.3.peg.3641; -.
DR Proteomes; UP000033604; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR Gene3D; 2.40.30.170; -; 1.
DR Gene3D; 2.40.420.20; -; 1.
DR Gene3D; 2.40.50.100; -; 1.
DR Gene3D; 1.10.287.470; Helix hairpin bin; 1.
DR InterPro; IPR039562; MFP_biotin_lipoyl_2.
DR InterPro; IPR006143; RND_pump_MFP.
DR NCBIfam; TIGR01730; RND_mfp; 1.
DR PANTHER; PTHR30469:SF15; HLYD FAMILY OF SECRETION PROTEINS; 1.
DR PANTHER; PTHR30469; MULTIDRUG RESISTANCE PROTEIN MDTA; 1.
DR Pfam; PF13533; Biotin_lipoyl_2; 1.
DR Pfam; PF13437; HlyD_3; 1.
DR SUPFAM; SSF111369; HlyD-like secretion proteins; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000033604};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 7..26
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 68..107
FT /note="Membrane fusion protein biotin-lipoyl like"
FT /evidence="ECO:0000259|Pfam:PF13533"
FT REGION 347..375
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 375 AA; 40049 MW; EC38877B43B75BB0 CRC64;
MKKAKTRIIW GIIIVAIAAF LIVRIFRKEE PVAPTPDPVV MVQPPAMGNI ELTTNLVGTI
EPADIVYIYP KAGGDVTAVN VKAGDTVAAG QVLVEIDTKQ VATSKNAMDT AKVAWDDAVS
TLNRMAPLHA SGFVSDKEFE GYQTAAEAKR LQYESAKIGY ETQMEFSHVT SPINGRVEQL
NVELHDTVGS SMQMCVIAGE SGNNVTFYVT EKVKNNLSLG APVTVTKEGN QYGGSVVEIN
NMAEASVGLF KVKASVDDQE TMAPGTSVEI QVPSASARNV MLIPNHCVYY KSGDAYVYTY
DQAEGVIHEV PVEVGIFDSE NISVLSGLTL DDMVLTTWTS ELKEGTKVTL DTGAGEDAGQ
TDEAESPAAD TSAAQ
//
