ID A0A0F0CFV3_9CLOT Unreviewed; 589 AA.
AC A0A0F0CFV3;
DT 24-JUN-2015, integrated into UniProtKB/TrEMBL.
DT 24-JUN-2015, sequence version 1.
DT 24-JAN-2024, entry version 28.
DE RecName: Full=Beta-glucuronidase {ECO:0000256|ARBA:ARBA00016205};
DE EC=3.2.1.31 {ECO:0000256|ARBA:ARBA00012761};
GN Name=uidA {ECO:0000313|EMBL:KJJ74685.1};
GN ORFNames=CLFS41_10760 {ECO:0000313|EMBL:KJJ74685.1};
OS Clostridium sp. FS41.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Clostridiaceae;
OC Clostridium.
OX NCBI_TaxID=1609975 {ECO:0000313|EMBL:KJJ74685.1, ECO:0000313|Proteomes:UP000033604};
RN [1] {ECO:0000313|EMBL:KJJ74685.1, ECO:0000313|Proteomes:UP000033604}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=FS41 {ECO:0000313|EMBL:KJJ74685.1,
RC ECO:0000313|Proteomes:UP000033604};
RA Poehlein A., Daniel R.;
RT "Genome sequencing of Clostridium sp. FS41.";
RL Submitted (FEB-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 2 family.
CC {ECO:0000256|ARBA:ARBA00007401}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KJJ74685.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; JYHN01000039; KJJ74685.1; -; Genomic_DNA.
DR RefSeq; WP_007870576.1; NZ_JYHN01000039.1.
DR AlphaFoldDB; A0A0F0CFV3; -.
DR PATRIC; fig|1609975.3.peg.1154; -.
DR Proteomes; UP000033604; Unassembled WGS sequence.
DR GO; GO:0004565; F:beta-galactosidase activity; IEA:UniProtKB-EC.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR Gene3D; 2.60.120.260; Galactose-binding domain-like; 1.
DR Gene3D; 3.20.20.80; Glycosidases; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR InterPro; IPR036156; Beta-gal/glucu_dom_sf.
DR InterPro; IPR008979; Galactose-bd-like_sf.
DR InterPro; IPR006101; Glyco_hydro_2.
DR InterPro; IPR023232; Glyco_hydro_2_AS.
DR InterPro; IPR006103; Glyco_hydro_2_cat.
DR InterPro; IPR006102; Glyco_hydro_2_Ig-like.
DR InterPro; IPR006104; Glyco_hydro_2_N.
DR InterPro; IPR017853; Glycoside_hydrolase_SF.
DR InterPro; IPR013783; Ig-like_fold.
DR PANTHER; PTHR10066; BETA-GLUCURONIDASE; 1.
DR PANTHER; PTHR10066:SF67; BETA-GLUCURONIDASE; 1.
DR Pfam; PF00703; Glyco_hydro_2; 1.
DR Pfam; PF02836; Glyco_hydro_2_C; 1.
DR Pfam; PF02837; Glyco_hydro_2_N; 1.
DR PRINTS; PR00132; GLHYDRLASE2.
DR SUPFAM; SSF51445; (Trans)glycosidases; 1.
DR SUPFAM; SSF49303; beta-Galactosidase/glucuronidase domain; 1.
DR SUPFAM; SSF49785; Galactose-binding domain-like; 1.
DR PROSITE; PS00608; GLYCOSYL_HYDROL_F2_2; 1.
DR PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
PE 3: Inferred from homology;
KW Glycosidase {ECO:0000256|ARBA:ARBA00023295, ECO:0000313|EMBL:KJJ74685.1};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000313|EMBL:KJJ74685.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000033604}.
FT DOMAIN 39..202
FT /note="Glycosyl hydrolases family 2 sugar binding"
FT /evidence="ECO:0000259|Pfam:PF02837"
FT DOMAIN 206..295
FT /note="Glycoside hydrolase family 2 immunoglobulin-like
FT beta-sandwich"
FT /evidence="ECO:0000259|Pfam:PF00703"
FT DOMAIN 300..585
FT /note="Glycoside hydrolase family 2 catalytic"
FT /evidence="ECO:0000259|Pfam:PF02836"
SQ SEQUENCE 589 AA; 68448 MW; C6AD366B2D618B0E CRC64;
MDRMKDDYKD ILDFQFDKKN QIAFTTVQSC VYTDHRKPES LDGVWGFTPD VFRSVTRKNL
FSASGKDEQG REVPMDLDFS SMEKIQVPGC WNCLDDRYWL YEGEAVYSRT FVYSKEKEGE
RIILRVGAAN YECRIWLNGT LLSRHQGGFT PFYTELTQDL KEINHIVITV NNRREPDQVP
SMNYDWFNYG GITRSVELFR LPAVYIKDFT ASLVPDGTYG RIELKIKLDA PVQGACCHFK
IEELGISREV LTDERGEARC VVQANPQLWD CEHPKLYEVQ ARCLEDQVKD RVGFREIRCD
GKDILLNGRK IYLKGVCCHE ESRNRGRIQT DEERLEILNT AKDMGCNILR LTHYPHSERM
AVLADQAGMM LWEEIPVYWA LDFENPETYS NAENQMRELM FRDKNRASVV IWSVGNENPD
IQSRLDFMKG LLETCRNYDP TRLTSAACLV DVNTMCVKDR LAEFVDVVAF NEYYGWYYRD
YEGVKVILDN TSIDKPMVIT ETGAGAKAGH HGGAEELFTE EHQERVYENQ IRYTDGRIQG
MFPWVLFDFI SPIRKHPMQG GKNSKGLVAM DKATRKKAFY VMQEYYRNK
//
