ID A0A0F0CMB9_9CLOT Unreviewed; 372 AA.
AC A0A0F0CMB9;
DT 24-JUN-2015, integrated into UniProtKB/TrEMBL.
DT 24-JUN-2015, sequence version 1.
DT 24-JAN-2024, entry version 21.
DE RecName: Full=UDP-N-acetylglucosamine 2-epimerase (non-hydrolyzing) {ECO:0000256|ARBA:ARBA00038858};
DE EC=5.1.3.14 {ECO:0000256|ARBA:ARBA00038858};
GN Name=mnaA {ECO:0000313|EMBL:KJJ77982.1};
GN ORFNames=CLFS41_00110 {ECO:0000313|EMBL:KJJ77982.1};
OS Clostridium sp. FS41.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Clostridiaceae;
OC Clostridium.
OX NCBI_TaxID=1609975 {ECO:0000313|EMBL:KJJ77982.1, ECO:0000313|Proteomes:UP000033604};
RN [1] {ECO:0000313|EMBL:KJJ77982.1, ECO:0000313|Proteomes:UP000033604}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=FS41 {ECO:0000313|EMBL:KJJ77982.1,
RC ECO:0000313|Proteomes:UP000033604};
RA Poehlein A., Daniel R.;
RT "Genome sequencing of Clostridium sp. FS41.";
RL Submitted (FEB-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=UDP-N-acetyl-alpha-D-glucosamine = UDP-N-acetyl-alpha-D-
CC mannosamine; Xref=Rhea:RHEA:17213, ChEBI:CHEBI:57705,
CC ChEBI:CHEBI:68623; EC=5.1.3.14;
CC Evidence={ECO:0000256|ARBA:ARBA00036080};
CC -!- SIMILARITY: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.
CC {ECO:0000256|ARBA:ARBA00038209, ECO:0000256|RuleBase:RU003513}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KJJ77982.1}.
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DR EMBL; JYHN01000003; KJJ77982.1; -; Genomic_DNA.
DR RefSeq; WP_045091075.1; NZ_JYHN01000003.1.
DR AlphaFoldDB; A0A0F0CMB9; -.
DR GeneID; 77446490; -.
DR PATRIC; fig|1609975.3.peg.15; -.
DR Proteomes; UP000033604; Unassembled WGS sequence.
DR GO; GO:0008761; F:UDP-N-acetylglucosamine 2-epimerase activity; IEA:UniProtKB-EC.
DR CDD; cd03786; GTB_UDP-GlcNAc_2-Epimerase; 1.
DR Gene3D; 3.40.50.2000; Glycogen Phosphorylase B; 2.
DR InterPro; IPR003331; UDP_GlcNAc_Epimerase_2_dom.
DR InterPro; IPR029767; WecB-like.
DR NCBIfam; TIGR00236; wecB; 1.
DR PANTHER; PTHR43174; UDP-N-ACETYLGLUCOSAMINE 2-EPIMERASE; 1.
DR PANTHER; PTHR43174:SF2; UDP-N-ACETYLGLUCOSAMINE 2-EPIMERASE; 1.
DR Pfam; PF02350; Epimerase_2; 1.
DR SUPFAM; SSF53756; UDP-Glycosyltransferase/glycogen phosphorylase; 1.
PE 3: Inferred from homology;
KW Isomerase {ECO:0000256|ARBA:ARBA00023235, ECO:0000256|RuleBase:RU003513};
KW Reference proteome {ECO:0000313|Proteomes:UP000033604}.
FT DOMAIN 23..362
FT /note="UDP-N-acetylglucosamine 2-epimerase"
FT /evidence="ECO:0000259|Pfam:PF02350"
SQ SEQUENCE 372 AA; 42377 MW; 2530B3562D906C02 CRC64;
MKKIMLVFGT RPEAIKMCPL VNELKKRKEI KTVVCVTGQH RQMLDQVLAT FNVIPDFDLS
IMKKGQTLFD ITTRILEKIR VILEKERPDV VLVHGDTSTT FATALACFYL QITVGHVEAG
LRTYNIYSPY PEEFNRQAVS IVSKFHFAPT KLAANHLIKE GKMKESIYIT GNTVIDAMQH
TVTEDYTHPE LDWVGEDKLI FITAHRRENL GLPMHNMFRA IRRVLDEHRD CKAVYPIHMN
PVVRKAADDE LGGCDRIHII EPIEVIDCHN FEARCFLCLT DSGGIQEEVP SYGKPVLVMR
DTTERTEGVD AGTLKLVGTD EETIYKNFKE LLDDKEVYNN MAQASNPYGD GHACKRIADI
LEYGTYEPWD AI
//
