ID A0A0F0H0W2_9ACTN Unreviewed; 759 AA.
AC A0A0F0H0W2;
DT 24-JUN-2015, integrated into UniProtKB/TrEMBL.
DT 24-JUN-2015, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=Alpha-N-acetylglucosaminidase {ECO:0000313|EMBL:KJK47293.1};
GN ORFNames=UK14_21080 {ECO:0000313|EMBL:KJK47293.1};
OS Streptomyces sp. NRRL F-4428.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1609137 {ECO:0000313|EMBL:KJK47293.1, ECO:0000313|Proteomes:UP000033569};
RN [1] {ECO:0000313|EMBL:KJK47293.1, ECO:0000313|Proteomes:UP000033569}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NRRL F-4428 {ECO:0000313|EMBL:KJK47293.1,
RC ECO:0000313|Proteomes:UP000033569};
RA Ju K.-S., Doroghazi J.R., Metcalf W.;
RL Submitted (FEB-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KJK47293.1}.
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DR EMBL; JYJI01000179; KJK47293.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0F0H0W2; -.
DR PATRIC; fig|1609137.3.peg.4861; -.
DR Proteomes; UP000033569; Unassembled WGS sequence.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:UniProt.
DR Gene3D; 3.30.379.10; Chitobiase/beta-hexosaminidase domain 2-like; 1.
DR Gene3D; 3.20.20.80; Glycosidases; 1.
DR Gene3D; 1.20.120.670; N-acetyl-b-d-glucoasminidase; 1.
DR InterPro; IPR029018; Hex-like_dom2.
DR InterPro; IPR007781; NAGLU.
DR InterPro; IPR024732; NAGLU_C.
DR InterPro; IPR024240; NAGLU_N.
DR InterPro; IPR024733; NAGLU_tim-barrel.
DR PANTHER; PTHR12872; ALPHA-N-ACETYLGLUCOSAMINIDASE; 1.
DR PANTHER; PTHR12872:SF1; ALPHA-N-ACETYLGLUCOSAMINIDASE; 1.
DR Pfam; PF05089; NAGLU; 1.
DR Pfam; PF12972; NAGLU_C; 1.
DR Pfam; PF12971; NAGLU_N; 1.
PE 4: Predicted;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Reference proteome {ECO:0000313|Proteomes:UP000033569};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..31
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 32..759
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5039572253"
FT DOMAIN 62..142
FT /note="Alpha-N-acetylglucosaminidase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF12971"
FT DOMAIN 156..475
FT /note="Alpha-N-acetylglucosaminidase tim-barrel"
FT /evidence="ECO:0000259|Pfam:PF05089"
FT DOMAIN 484..747
FT /note="Alpha-N-acetylglucosaminidase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF12972"
SQ SEQUENCE 759 AA; 81751 MW; 00A5A5BD7AE9DC9E CRC64;
MPGPRRPATR PVARPVALAA LCATLLAVVC AAPAPGATAP GTGSSARAGV RLLPGATFDT
APARAALERL LPRHASQFTL VADPAAGADT FTVSGTAGAI TVRGSTGATL LTGVGWYLQH
VAGADIGWPG DSIGMLPARL PAVPAPVTRS ALVPHRYALN DTDDGYSGPY RTFEEHQRQI
DLLALHGINE VFVQVGAEYP YHRALQRFGY SAEELRQWIP GPAHQSWWLL QNLSGFGGPV
SERLMRERAE LGGRIADQLR GLGMTPVLPG YFGTVPPGFA ARNAGAATVA QGDWAGFDRP
DWLDPASPVF AKLAAAYYAE QRAVFGDSTM YRMSPLHEGG QTGSVDVGAA AGAIQAALHA
AHPGALWAVL GWQDDPTPEL LAGVDTSRLL ILDGLSDRYN RLDRETRWGG APYAMGTIYN
FGGHTTVGAN TSVWLERFGP WRAKGNSALA GIAYLPEATG TNPAAFDLFT DLAWDAGPID
HRAWFAGFAA RRYGRPDAEA AAAWEELRKG PYSTSSGLWS ESQDSLFSAR PSLSAAGAAH
WSPKTMRYPA GSVRRALDHL LKVDPALRGS SAYRFDLVDT ARQALANHSR VLLPRIKAAY
EAKDLARFRT LTAEWQDAMR LLDQVTGSDP NLLLGTWLAR ARSQGADRAE QDRYEYDARS
LLSVWGRRST SEGGFLHDYA NREWSGLVSE LYARRWAAYF AALDEALVRK AQPREIDWHA
FEEEWARRTT RHPERPGGDP HRLAAAVAAA LPPAAAGHA
//
