ID A0A0F0HT12_9PSEU Unreviewed; 427 AA.
AC A0A0F0HT12;
DT 24-JUN-2015, integrated into UniProtKB/TrEMBL.
DT 24-JUN-2015, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE RecName: Full=Signal transduction histidine kinase subgroup 3 dimerisation and phosphoacceptor domain-containing protein {ECO:0000259|Pfam:PF07730};
GN ORFNames=UK12_16250 {ECO:0000313|EMBL:KJK57512.1};
OS Saccharothrix sp. ST-888.
OC Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
OC Pseudonocardiaceae; Saccharothrix.
OX NCBI_TaxID=1427391 {ECO:0000313|EMBL:KJK57512.1, ECO:0000313|Proteomes:UP000033409};
RN [1] {ECO:0000313|EMBL:KJK57512.1, ECO:0000313|Proteomes:UP000033409}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ST-888 {ECO:0000313|EMBL:KJK57512.1,
RC ECO:0000313|Proteomes:UP000033409};
RA Ju K.-S., Doroghazi J.R., Metcalf W.;
RL Submitted (FEB-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KJK57512.1}.
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DR EMBL; JYJF01000044; KJK57512.1; -; Genomic_DNA.
DR RefSeq; WP_045303687.1; NZ_JYJF01000044.1.
DR AlphaFoldDB; A0A0F0HT12; -.
DR PATRIC; fig|1427391.3.peg.4871; -.
DR OrthoDB; 227596at2; -.
DR Proteomes; UP000033409; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR GO; GO:0046983; F:protein dimerization activity; IEA:InterPro.
DR CDD; cd16917; HATPase_UhpB-NarQ-NarX-like; 1.
DR Gene3D; 1.20.5.1930; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR011712; Sig_transdc_His_kin_sub3_dim/P.
DR PANTHER; PTHR24421; NITRATE/NITRITE SENSOR PROTEIN NARX-RELATED; 1.
DR PANTHER; PTHR24421:SF10; SENSORY TRANSDUCTION HISTIDINE KINASE; 1.
DR Pfam; PF07730; HisKA_3; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
PE 4: Predicted;
KW Kinase {ECO:0000256|ARBA:ARBA00022777}; Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000033409};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius};
KW Two-component regulatory system {ECO:0000256|ARBA:ARBA00023012}.
FT TRANSMEM 12..35
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 47..66
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 104..131
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 159..182
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 211..275
FT /note="Signal transduction histidine kinase subgroup 3
FT dimerisation and phosphoacceptor"
FT /evidence="ECO:0000259|Pfam:PF07730"
SQ SEQUENCE 427 AA; 45652 MW; C203A97D1E0B4CFA CRC64;
MHRTIRPLCR RSTYSGAVFA FIGAAMNVFL LPFALVPVGL WQVPSTSLRT ALFAAAMVAL
IVLLGLPRAT RLISVALANR LLGAELPEPA KRPRSRWSTR MRTAAWLQLH IGLGGLLAGL
VLLLLMAGLV LPGTWLSGGD QIAYFGLSVD IVPGWRGAWV WPAAAAALVM SAQACATTTA
FLRVMAQRLL GHSAAERLAE LEERQLILAQ RNRLAQELHD SIGHTLTAST IQAAVAGELL
VADPDAARRA LRSIEESSRS ALDDLDHVLG ALRDDASATV PDRTLANVHD LFERIRQAGA
ELQVDIAGDL AQVPATVSRE AYRIVQEGLT NAMRHGDQAG PVTVTVRADL AWLEIVVVNA
VSDRHSAATR TGGGRGLVGV TERVQLLRGE VMAGPAASDP IRPETTVPHP AGGYWKLVVR
VPLRLAV
//
