ID A0A0F0HUZ1_9PSEU Unreviewed; 420 AA.
AC A0A0F0HUZ1;
DT 24-JUN-2015, integrated into UniProtKB/TrEMBL.
DT 24-JUN-2015, sequence version 1.
DT 24-JAN-2024, entry version 25.
DE SubName: Full=Glycosyl transferase {ECO:0000313|EMBL:KJK59344.1};
GN ORFNames=UK12_04865 {ECO:0000313|EMBL:KJK59344.1};
OS Saccharothrix sp. ST-888.
OC Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
OC Pseudonocardiaceae; Saccharothrix.
OX NCBI_TaxID=1427391 {ECO:0000313|EMBL:KJK59344.1, ECO:0000313|Proteomes:UP000033409};
RN [1] {ECO:0000313|EMBL:KJK59344.1, ECO:0000313|Proteomes:UP000033409}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ST-888 {ECO:0000313|EMBL:KJK59344.1,
RC ECO:0000313|Proteomes:UP000033409};
RA Ju K.-S., Doroghazi J.R., Metcalf W.;
RL Submitted (FEB-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- PATHWAY: Antibiotic biosynthesis; vancomycin biosynthesis.
CC {ECO:0000256|ARBA:ARBA00004660}.
CC -!- SIMILARITY: Belongs to the glycosyltransferase 28 family.
CC {ECO:0000256|ARBA:ARBA00006962}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KJK59344.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; JYJF01000006; KJK59344.1; -; Genomic_DNA.
DR RefSeq; WP_045299871.1; NZ_JYJF01000006.1.
DR AlphaFoldDB; A0A0F0HUZ1; -.
DR PATRIC; fig|1427391.3.peg.5319; -.
DR OrthoDB; 3253247at2; -.
DR UniPathway; UPA00162; -.
DR Proteomes; UP000033409; Unassembled WGS sequence.
DR GO; GO:0016758; F:hexosyltransferase activity; IEA:InterPro.
DR GO; GO:0008194; F:UDP-glycosyltransferase activity; IEA:InterPro.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR GO; GO:0030259; P:lipid glycosylation; IEA:InterPro.
DR GO; GO:0033072; P:vancomycin biosynthetic process; IEA:UniProtKB-UniPathway.
DR CDD; cd03784; GT1_Gtf-like; 1.
DR Gene3D; 3.40.50.2000; Glycogen Phosphorylase B; 2.
DR InterPro; IPR010610; EryCIII-like_C.
DR InterPro; IPR004276; GlycoTrans_28_N.
DR InterPro; IPR002213; UDP_glucos_trans.
DR PANTHER; PTHR48050; STEROL 3-BETA-GLUCOSYLTRANSFERASE; 1.
DR PANTHER; PTHR48050:SF13; UDP-GLUCURONOSYLTRANSFERASE; 1.
DR Pfam; PF06722; EryCIII-like_C; 1.
DR Pfam; PF03033; Glyco_transf_28; 1.
DR SUPFAM; SSF53756; UDP-Glycosyltransferase/glycogen phosphorylase; 1.
PE 3: Inferred from homology;
KW Antibiotic biosynthesis {ECO:0000256|ARBA:ARBA00023194};
KW Reference proteome {ECO:0000313|Proteomes:UP000033409};
KW Transferase {ECO:0000313|EMBL:KJK59344.1}.
FT DOMAIN 4..145
FT /note="Glycosyltransferase family 28 N-terminal"
FT /evidence="ECO:0000259|Pfam:PF03033"
FT DOMAIN 297..417
FT /note="Erythromycin biosynthesis protein CIII-like C-
FT terminal"
FT /evidence="ECO:0000259|Pfam:PF06722"
SQ SEQUENCE 420 AA; 44259 MW; 747136D7DA01D08D CRC64;
MRIQLITVGT MGSVAPYTGL GHRLADEGHE VEIVTHAKFA EVVGCCGLRM RPLAADPFEA
LIGAHSRLQG AQGSPDAPGA LRALWSLRSA TGLATLGLVD GILDAVDPTA DLILLSTLAA
PIGAQVAEYH RIPSIGVFLQ PEVPTREFAP CATAWRPPGR ANLLRGRAAN VLLDSFYGAA
RRRLHTRLGL THRSGHRLRS ARERNRWPIW HGYSPSVVPR PADWRPGLHV AGYWWPHECP
NWQPPALVAD FLTAGPPPVL IGFGSMMPGD PRRLGEIAAR ALRQAGLRGI VQSGSVGLSV
VDDDVITVGA LPHGWLMPRT AAVVHHAGAG TTAAALRAGV PAVPVPVMTD QPWWAARLVQ
LGVSPQVLPC TELTAGRLAE ALGRATGDAG FARRSGALAA RLADEDGSGA VARAVAELAG
//
