ID A0A0F0IDY7_ASPPU Unreviewed; 887 AA.
AC A0A0F0IDY7;
DT 24-JUN-2015, integrated into UniProtKB/TrEMBL.
DT 24-JUN-2015, sequence version 1.
DT 27-MAR-2024, entry version 31.
DE SubName: Full=M28 Zn-peptidase Transferrin Receptor-like family protein {ECO:0000313|EMBL:KJK64922.1};
GN ORFNames=P875_00010794 {ECO:0000313|EMBL:KJK64922.1};
OS Aspergillus parasiticus (strain ATCC 56775 / NRRL 5862 / SRRC 143 / SU-1).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus.
OX NCBI_TaxID=1403190 {ECO:0000313|EMBL:KJK64922.1, ECO:0000313|Proteomes:UP000033540};
RN [1] {ECO:0000313|EMBL:KJK64922.1, ECO:0000313|Proteomes:UP000033540}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 56775 / NRRL 5862 / SRRC 143 / SU-1
RC {ECO:0000313|Proteomes:UP000033540};
RA Yu J., Fedorova N., Yin Y., Losada L., Zafar N., Taujale R., Ehrlich K.C.,
RA Bhatnagar D., Cleveland T.E., Bennett J.W., Nierman W.C.;
RT "Draft genome sequence of Aspergillus parasiticus SU-1.";
RL Submitted (FEB-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the peptidase M28 family. M28B subfamily.
CC {ECO:0000256|ARBA:ARBA00005634}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KJK64922.1}.
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DR EMBL; JZEE01000380; KJK64922.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0F0IDY7; -.
DR STRING; 1403190.A0A0F0IDY7; -.
DR Proteomes; UP000033540; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR CDD; cd08022; M28_PSMA_like; 1.
DR CDD; cd02121; PA_GCPII_like; 1.
DR Gene3D; 3.50.30.30; -; 1.
DR Gene3D; 1.20.930.40; Transferrin receptor-like, dimerisation domain; 1.
DR Gene3D; 3.40.630.10; Zn peptidases; 1.
DR InterPro; IPR046450; PA_dom_sf.
DR InterPro; IPR003137; PA_domain.
DR InterPro; IPR007484; Peptidase_M28.
DR InterPro; IPR039373; Peptidase_M28B.
DR InterPro; IPR007365; TFR-like_dimer_dom.
DR InterPro; IPR036757; TFR-like_dimer_dom_sf.
DR PANTHER; PTHR10404:SF71; CARBOXYPEPTIDASE TRE2, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G10650)-RELATED; 1.
DR PANTHER; PTHR10404; N-ACETYLATED-ALPHA-LINKED ACIDIC DIPEPTIDASE; 1.
DR Pfam; PF02225; PA; 1.
DR Pfam; PF04389; Peptidase_M28; 1.
DR Pfam; PF04253; TFR_dimer; 1.
DR SUPFAM; SSF52025; PA domain; 1.
DR SUPFAM; SSF47672; Transferrin receptor-like dimerisation domain; 1.
DR SUPFAM; SSF53187; Zn-dependent exopeptidases; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Receptor {ECO:0000313|EMBL:KJK64922.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000033540};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 167..185
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 310..395
FT /note="PA"
FT /evidence="ECO:0000259|Pfam:PF02225"
FT DOMAIN 499..682
FT /note="Peptidase M28"
FT /evidence="ECO:0000259|Pfam:PF04389"
FT DOMAIN 759..884
FT /note="Transferrin receptor-like dimerisation"
FT /evidence="ECO:0000259|Pfam:PF04253"
FT REGION 1..91
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 40..58
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 887 AA; 99352 MW; B10C53FDB93DB085 CRC64;
MGNDSKFEYE ALPIPSYEEA VGARPSSSRS NLGPEANDES ERQGLLHNVD DVTARESARP
RPHGYQPPTV ESVRDSLDGL DSTGADSERG SLEELQRELH EMDVEDGDQQ SSQRSRLLRS
RFSKRISSLT RSLSAIHLPI RRFLPSFRFT IDLNGARTNM RTHGCMIMLR LFGLFLVVLV
VYIFFVSDLF NMNSRFIMGQ SYSAASVENF VQGHVNETNI AENLKRVTNF THMAGTEGSY
ALAEWVKQEF KIAGLDDIEM EEFQVYLNYP RDDGRRVAIV DPPDLSWEAT LEETNEEMPV
FHGHSKAGNV TGPIVYANYG SREDFQYLAD QGVTVEGSIA LVRYYGSESD RALKIKAAEL
AGAVGCIIYS DPSEDGFVRG PAYPDGRFMP EDGVQRGGVS LMSWVVGDVL SPGFASTPDE
KKRLKPEESQ GLTSIPSLPI AWRDAQRLLQ VIKGHGSQVP AKWVGGVPNV DQWWTGDGTS
PKVNLMNLQD EEERQPIYNV LGRIIGLEQP EKKIIVGNHR DSWCLGSADP GSGTAVFLEV
VRVFGELRTF GWRPLRTIEF VSWDAEEYNL IGSTEHVEKE LEKLREHAYA YMNVDVGVSG
SEFEASGCPL FERVVTQILG RISDPVANET LKEIWEKKQK KLGPLGAGSD YVAFQDIAGT
SSVDFGFVGE PYPYHSCYEN WDWMVRFGDP GFQYHKILAQ FWGLLILQFA DTPVLPFDLE
VYADHIASYV IDLEKYAKSQ NVPIAHDASS GKSNREVTVT FKPLYDAAAK VKDDAAQFQQ
WARVWHDTVL GTGGFENNVI AAQRMDHNAR MARFDTHLLD DRVDGGVPNR TQFKHVLFGP
ELWSGYDATF FPAIRDSIDS RNWTLTQEWV DRVSDILSTA GDKLLHG
//
