ID A0A0F0IG02_ASPPU Unreviewed; 461 AA.
AC A0A0F0IG02;
DT 24-JUN-2015, integrated into UniProtKB/TrEMBL.
DT 24-JUN-2015, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE RecName: Full=Zinc transporter {ECO:0000256|RuleBase:RU369017};
GN ORFNames=P875_00127814 {ECO:0000313|EMBL:KJK66749.1};
OS Aspergillus parasiticus (strain ATCC 56775 / NRRL 5862 / SRRC 143 / SU-1).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus.
OX NCBI_TaxID=1403190 {ECO:0000313|EMBL:KJK66749.1, ECO:0000313|Proteomes:UP000033540};
RN [1] {ECO:0000313|EMBL:KJK66749.1, ECO:0000313|Proteomes:UP000033540}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 56775 / NRRL 5862 / SRRC 143 / SU-1
RC {ECO:0000313|Proteomes:UP000033540};
RA Yu J., Fedorova N., Yin Y., Losada L., Zafar N., Taujale R., Ehrlich K.C.,
RA Bhatnagar D., Cleveland T.E., Bennett J.W., Nierman W.C.;
RT "Draft genome sequence of Aspergillus parasiticus SU-1.";
RL Submitted (FEB-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Functions as a zinc transporter.
CC {ECO:0000256|RuleBase:RU369017}.
CC -!- SUBCELLULAR LOCATION: Endoplasmic reticulum membrane
CC {ECO:0000256|RuleBase:RU369017}; Multi-pass membrane protein
CC {ECO:0000256|RuleBase:RU369017}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the cation diffusion facilitator (CDF)
CC transporter (TC 2.A.4) family. SLC30A subfamily.
CC {ECO:0000256|RuleBase:RU369017}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KJK66749.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; JZEE01000232; KJK66749.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0F0IG02; -.
DR STRING; 1403190.A0A0F0IG02; -.
DR Proteomes; UP000033540; Unassembled WGS sequence.
DR GO; GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005385; F:zinc ion transmembrane transporter activity; IEA:UniProtKB-UniRule.
DR GO; GO:0006882; P:intracellular zinc ion homeostasis; IEA:InterPro.
DR Gene3D; 1.20.1510.10; Cation efflux protein transmembrane domain; 1.
DR InterPro; IPR002524; Cation_efflux.
DR InterPro; IPR027469; Cation_efflux_TMD_sf.
DR InterPro; IPR045316; Msc2-like.
DR PANTHER; PTHR45755; -; 1.
DR PANTHER; PTHR45755:SF5; ZINC TRANSPORTER; 1.
DR Pfam; PF01545; Cation_efflux; 1.
DR SUPFAM; SSF161111; Cation efflux protein transmembrane domain-like; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Endoplasmic reticulum {ECO:0000256|RuleBase:RU369017};
KW Ion transport {ECO:0000256|RuleBase:RU369017};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU369017};
KW Reference proteome {ECO:0000313|Proteomes:UP000033540};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU369017};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|RuleBase:RU369017}; Transport {ECO:0000256|RuleBase:RU369017}.
FT TRANSMEM 160..177
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU369017"
FT TRANSMEM 189..207
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU369017"
FT TRANSMEM 228..250
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU369017"
FT TRANSMEM 270..293
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU369017"
FT TRANSMEM 314..337
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU369017"
FT TRANSMEM 343..364
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU369017"
FT REGION 1..90
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 410..437
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 7..24
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 45..90
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 461 AA; 50473 MW; 09FF373766AF286F CRC64;
MASNLPIPLP PRTPTPPPDD PPNAPDNSSR LDAQDKDSLS PLVDSFPPQR GSLNTEGSNR
LSPTRASFTL STSDNVPQNS QGDNGSAGPF NFKTTTMAKS PVVKSNIGQR RGHKYKHSSI
SHQIFLEPPP RAPLALPNSL PIPTFKECRA SMSKDQKTRF WWSVCHMFVA AYTLWSAHGS
LAMTALSHLI LFDSLGALLC VSVDVLSNFE VWKRSSVRHP FGLERAEVLA GFAMCVLLLF
MGMDLISHNL QHFLESSGHE PHHSHAHERV SVGSVDVTAL LAISSTLISA IGLKNHGRIG
KAMRFGYIES LPSVLSNPSH FLTLSCSTLL LLLPLVSVRL YNWLDVLLSS TIAISMCVIG
VRLVKTLGSM LLMSYSGPGV NDVIRDIEAD PSVFGVDDAR FWQVHYGLCM ANLKLRVSGS
EENLIRLRER ISSLIRNRLG GGYGSGGQRW EVSLQFTIEK S
//
