ID A0A0F0KB09_9MICO Unreviewed; 780 AA.
AC A0A0F0KB09;
DT 24-JUN-2015, integrated into UniProtKB/TrEMBL.
DT 24-JUN-2015, sequence version 1.
DT 24-JAN-2024, entry version 21.
DE SubName: Full=ComEC family competence protein {ECO:0000313|EMBL:KJL17360.1};
GN ORFNames=RL72_03604 {ECO:0000313|EMBL:KJL17360.1};
OS Microbacterium azadirachtae.
OC Bacteria; Actinomycetota; Actinomycetes; Micrococcales; Microbacteriaceae;
OC Microbacterium.
OX NCBI_TaxID=582680 {ECO:0000313|EMBL:KJL17360.1, ECO:0000313|Proteomes:UP000033448};
RN [1] {ECO:0000313|EMBL:KJL17360.1, ECO:0000313|Proteomes:UP000033448}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 23848 {ECO:0000313|EMBL:KJL17360.1,
RC ECO:0000313|Proteomes:UP000033448};
RA Corretto E.;
RT "Draft genome sequences of ten Microbacterium spp. with emphasis on heavy
RT metal contaminated environments.";
RL Submitted (FEB-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KJL17360.1}.
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DR EMBL; JYIT01000086; KJL17360.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0F0KB09; -.
DR PATRIC; fig|582680.7.peg.3662; -.
DR OrthoDB; 7177610at2; -.
DR Proteomes; UP000033448; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR CDD; cd07731; ComA-like_MBL-fold; 1.
DR Gene3D; 3.60.15.10; Ribonuclease Z/Hydroxyacylglutathione hydrolase-like; 1.
DR InterPro; IPR035681; ComA-like_MBL.
DR InterPro; IPR004477; ComEC_N.
DR InterPro; IPR001279; Metallo-B-lactamas.
DR InterPro; IPR036866; RibonucZ/Hydroxyglut_hydro.
DR NCBIfam; TIGR00360; ComEC_N-term; 1.
DR PANTHER; PTHR30619; DNA INTERNALIZATION/COMPETENCE PROTEIN COMEC/REC2; 1.
DR PANTHER; PTHR30619:SF1; RECOMBINATION PROTEIN 2; 1.
DR Pfam; PF03772; Competence; 1.
DR Pfam; PF00753; Lactamase_B; 1.
DR SMART; SM00849; Lactamase_B; 1.
DR SUPFAM; SSF56281; Metallo-hydrolase/oxidoreductase; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000033448};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 6..39
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 51..74
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 237..258
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 265..281
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 310..327
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 333..350
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 362..384
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 429..449
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 455..474
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 486..505
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 527..716
FT /note="Metallo-beta-lactamase"
FT /evidence="ECO:0000259|SMART:SM00849"
SQ SEQUENCE 780 AA; 78990 MW; 8CA501D585D64453 CRC64;
MVPVAVTAWL AGLLVSFLPA SGGPLAGATA LAVVLILFAR RRPGNGAAAR LLAHAGPLAV
VCLAVAAAIG LSAAGDAPAR DRAAAFAGHV VGAEVSVRSL PSLGADGRLW ADADAVRLGT
GDDPAPLSVP VRVGVRSEER WSSLGPGTVL RFTAQVKAAD AGERAAVVLF AQQPVVQVSR
GGPVETIAGD VRAAFIVRAQ RLPEPGSELL PGLAVGDVRS VSAELGDAMK ASGLSHLTAV
SGSNLALVAA AAFGVVALCG GGRRTRVAVA ALALAGFVVL VTPQPSVIRA AAMAAAAMTA
LLLGRPRAGL SVLLLAVTVL LLTDPRLAAA PGFALSAAAT AGLIVLAPPL SDGLARWLPR
PVALAVSVPL SAQLACGPII ALFAAQQSLV SVVANLLAEP ASPIATVLGL LACLTLPIPP
LADLLAATAW LPSAWIAQTA VATAGLPIAT IEVPAGILTS LAVAALSAAA FWVIAPHRPL
PHPWRAIVGG AVAVLLGVSA GWGLVSGPVV LLQRPADWGI AMCDIGQGDA ILVRSAGSTM
LIDTGPDPKP LQRCLTDLGV DRLDVLVLTH FDHDHAGASD LLRGRADVVL HGPVDTAAHQ
GQLDRLRNGG ARLIDAAAGM TGHLGGADWR VLWPRRAEKV FPPGNDVGVI LEVAGGGVPR
SLFLADLSAA SQGMLRRMAH PRHMTVVKVA HHGSADQDPQ LYADLDPALA LISVGAGNDY
GHPRASTLEM LSALQTPVLR TDQRGTILVA EGEDGLRVWT ARPVPAETPG PTPGTTARAP
//
