ID   A0A0F0KIM3_9MICO        Unreviewed;       371 AA.
AC   A0A0F0KIM3;
DT   24-JUN-2015, integrated into UniProtKB/TrEMBL.
DT   24-JUN-2015, sequence version 1.
DT   27-MAR-2024, entry version 27.
DE   RecName: Full=adenosine deaminase {ECO:0000256|ARBA:ARBA00012784};
DE            EC=3.5.4.4 {ECO:0000256|ARBA:ARBA00012784};
GN   ORFNames=RL72_02657 {ECO:0000313|EMBL:KJL20732.1};
OS   Microbacterium azadirachtae.
OC   Bacteria; Actinomycetota; Actinomycetes; Micrococcales; Microbacteriaceae;
OC   Microbacterium.
OX   NCBI_TaxID=582680 {ECO:0000313|EMBL:KJL20732.1, ECO:0000313|Proteomes:UP000033448};
RN   [1] {ECO:0000313|EMBL:KJL20732.1, ECO:0000313|Proteomes:UP000033448}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 23848 {ECO:0000313|EMBL:KJL20732.1,
RC   ECO:0000313|Proteomes:UP000033448};
RA   Corretto E.;
RT   "Draft genome sequences of ten Microbacterium spp. with emphasis on heavy
RT   metal contaminated environments.";
RL   Submitted (FEB-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- COFACTOR:
CC       Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC         Evidence={ECO:0000256|ARBA:ARBA00001947};
CC   -!- SIMILARITY: Belongs to the metallo-dependent hydrolases superfamily.
CC       Adenosine and AMP deaminases family. {ECO:0000256|ARBA:ARBA00006676}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KJL20732.1}.
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DR   EMBL; JYIT01000082; KJL20732.1; -; Genomic_DNA.
DR   RefSeq; WP_045251336.1; NZ_JYIT01000082.1.
DR   AlphaFoldDB; A0A0F0KIM3; -.
DR   PATRIC; fig|582680.7.peg.2712; -.
DR   OrthoDB; 9779574at2; -.
DR   Proteomes; UP000033448; Unassembled WGS sequence.
DR   GO; GO:0004000; F:adenosine deaminase activity; IEA:UniProt.
DR   Gene3D; 3.20.20.140; Metal-dependent hydrolases; 1.
DR   InterPro; IPR001365; A_deaminase_dom.
DR   InterPro; IPR006330; Ado/ade_deaminase.
DR   InterPro; IPR032466; Metal_Hydrolase.
DR   NCBIfam; TIGR01430; aden_deam; 1.
DR   PANTHER; PTHR11409; ADENOSINE DEAMINASE; 1.
DR   PANTHER; PTHR11409:SF43; ADENOSINE DEAMINASE; 1.
DR   Pfam; PF00962; A_deaminase; 1.
DR   SUPFAM; SSF51556; Metallo-dependent hydrolases; 1.
PE   3: Inferred from homology;
KW   Hydrolase {ECO:0000313|EMBL:KJL20732.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000033448}.
FT   DOMAIN          20..367
FT                   /note="Adenosine deaminase"
FT                   /evidence="ECO:0000259|Pfam:PF00962"
SQ   SEQUENCE   371 AA;  40633 MW;  719157B24049A177 CRC64;
     MPIDANGDLE VEGLSLRSLP KVSLHDHLDG GVRPATIIEL ADAAGIELPH TDATALGMWF
     RTQASAGSLV DYLKTFDVSL SVMQTAENLR RISREFVEDL VRDGVVYGEV RWAPELHLTS
     GLTLQQAVDA VQDGIDEAED AAESRGKSIR VGQLLSAMRQ TDRVREIAEL AVANRDRGVV
     GFDTAGPEAG YPSSRYRETF EYLAQQMFPI TVHAGEAAGP DSIRSALVDG RALRLGHGVR
     IAEDLEIVNR DGEEVQVRFG DLARWVRDRE IPLELSPSSN LQTGAIAAWG SEFADHPFDL
     LYQLGFAVTV NVDNRTMSAT SLTREMALLV DSFGYDLEDL ESFQFNAAAG AFLPVEEREE
     LVELIAEGFD E
//