ID   A0A0F0KLS6_9MICO        Unreviewed;       597 AA.
AC   A0A0F0KLS6;
DT   24-JUN-2015, integrated into UniProtKB/TrEMBL.
DT   24-JUN-2015, sequence version 1.
DT   27-MAR-2024, entry version 28.
DE   SubName: Full=Putative ketoacyl reductase {ECO:0000313|EMBL:KJL21115.1};
DE            EC=1.3.1.- {ECO:0000313|EMBL:KJL21115.1};
GN   Name=actIII_1 {ECO:0000313|EMBL:KJL21115.1};
GN   ORFNames=RN50_01799 {ECO:0000313|EMBL:KJL21115.1};
OS   Microbacterium foliorum.
OC   Bacteria; Actinomycetota; Actinomycetes; Micrococcales; Microbacteriaceae;
OC   Microbacterium.
OX   NCBI_TaxID=104336 {ECO:0000313|EMBL:KJL21115.1, ECO:0000313|Proteomes:UP000033572};
RN   [1] {ECO:0000313|EMBL:KJL21115.1, ECO:0000313|Proteomes:UP000033572}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 12966 {ECO:0000313|EMBL:KJL21115.1,
RC   ECO:0000313|Proteomes:UP000033572};
RA   Corretto E.;
RT   "Draft genome sequences of ten Microbacterium spp. with emphasis on heavy
RT   metal contaminated environments.";
RL   Submitted (FEB-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the short-chain dehydrogenases/reductases (SDR)
CC       family. {ECO:0000256|ARBA:ARBA00006484}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KJL21115.1}.
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DR   EMBL; JYIU01000041; KJL21115.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A0F0KLS6; -.
DR   PATRIC; fig|104336.4.peg.1838; -.
DR   Proteomes; UP000033572; Unassembled WGS sequence.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR   Gene3D; 3.90.1200.10; -; 1.
DR   Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR   InterPro; IPR002575; Aminoglycoside_PTrfase.
DR   InterPro; IPR011009; Kinase-like_dom_sf.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   InterPro; IPR002347; SDR_fam.
DR   PANTHER; PTHR42879; 3-OXOACYL-(ACYL-CARRIER-PROTEIN) REDUCTASE; 1.
DR   PANTHER; PTHR42879:SF2; 3-OXOACYL-[ACYL-CARRIER-PROTEIN] REDUCTASE FABG; 1.
DR   Pfam; PF13561; adh_short_C2; 1.
DR   Pfam; PF01636; APH; 1.
DR   PRINTS; PR00081; GDHRDH.
DR   PRINTS; PR00080; SDRFAMILY.
DR   SMART; SM00822; PKS_KR; 1.
DR   SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR   SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
PE   3: Inferred from homology;
KW   Oxidoreductase {ECO:0000313|EMBL:KJL21115.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000033572}.
FT   DOMAIN          332..529
FT                   /note="Aminoglycoside phosphotransferase"
FT                   /evidence="ECO:0000259|Pfam:PF01636"
SQ   SEQUENCE   597 AA;  63204 MW;  F2EE21E4F745ADFB CRC64;
     MTSPHLPVAL ITGVGSEHGI GFAVARRLGA ERMRLVLTST TERIFGRVDE LRAAGVEAVG
     IVADLTRQSG VDAVIACAQE TYGCVDVLVN NAGMTSVSDP DEPGAIDELS ADRWHASLER
     NLTTTFSVIR AVVGGMRDRG YGRIVNVSSV SGPVAAFVGD VAYHAAKAGV VGLTRAAAVE
     VAPAGITVNA VAPGWIDTAS ATDRERAMGA ATPVGRSGTA DEVASVIGFL ADEAASYITG
     QLITVDGGQL HHRRTRALRP VTKERRELTM NENTLGFDFF EAGELPAPIV TAALAERWAE
     EAFGLVVDAV DLGSQQDANF LLIARGGVSG DRVAVMKVSN SAFDVEAVDD QDRAAQWAVD
     AVPGLRAPTR IGDVALLEAP SGTHVVRLIR YLDGGTLHGS APLSPRSVAA MGRVCGEMSA
     ALSSLPHTPA ERVLQWDLRQ GSRVVEFLAE HIPDAVLRER LVRVARAEAA RVERVAALLP
     VQVVHGDLTD DNLMRSASRG DDRVLDGVID FGDLMLSWRV AELATTISSV LHHDGASASS
     VLPAVREFHR IRPLSIPEVE ALWPLVIMRG AVLVTSGHQQ VGTDDSNEYA RDGLARE
//