ID A0A0F0KYV3_9MICO Unreviewed; 1020 AA.
AC A0A0F0KYV3;
DT 24-JUN-2015, integrated into UniProtKB/TrEMBL.
DT 24-JUN-2015, sequence version 1.
DT 27-MAR-2024, entry version 39.
DE RecName: Full=RNA polymerase sigma factor {ECO:0000256|RuleBase:RU362124};
GN Name=sigB {ECO:0000313|EMBL:KJL26048.1};
GN ORFNames=RN50_00333 {ECO:0000313|EMBL:KJL26048.1};
OS Microbacterium foliorum.
OC Bacteria; Actinomycetota; Actinomycetes; Micrococcales; Microbacteriaceae;
OC Microbacterium.
OX NCBI_TaxID=104336 {ECO:0000313|EMBL:KJL26048.1, ECO:0000313|Proteomes:UP000033572};
RN [1] {ECO:0000313|EMBL:KJL26048.1, ECO:0000313|Proteomes:UP000033572}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 12966 {ECO:0000313|EMBL:KJL26048.1,
RC ECO:0000313|Proteomes:UP000033572};
RA Corretto E.;
RT "Draft genome sequences of ten Microbacterium spp. with emphasis on heavy
RT metal contaminated environments.";
RL Submitted (FEB-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Sigma factors are initiation factors that promote the
CC attachment of RNA polymerase to specific initiation sites and are then
CC released. {ECO:0000256|RuleBase:RU362124}.
CC -!- SIMILARITY: Belongs to the sigma-70 factor family.
CC {ECO:0000256|RuleBase:RU362124}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KJL26048.1}.
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DR EMBL; JYIU01000024; KJL26048.1; -; Genomic_DNA.
DR RefSeq; WP_052677586.1; NZ_JYIU01000024.1.
DR AlphaFoldDB; A0A0F0KYV3; -.
DR PATRIC; fig|104336.4.peg.346; -.
DR Proteomes; UP000033572; Unassembled WGS sequence.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0016987; F:sigma factor activity; IEA:UniProtKB-KW.
DR GO; GO:0006352; P:DNA-templated transcription initiation; IEA:InterPro.
DR CDD; cd06171; Sigma70_r4; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR Gene3D; 1.10.601.10; RNA Polymerase Primary Sigma Factor; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR014284; RNA_pol_sigma-70_dom.
DR InterPro; IPR000943; RNA_pol_sigma70.
DR InterPro; IPR007627; RNA_pol_sigma70_r2.
DR InterPro; IPR007630; RNA_pol_sigma70_r4.
DR InterPro; IPR013325; RNA_pol_sigma_r2.
DR InterPro; IPR013324; RNA_pol_sigma_r3/r4-like.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR NCBIfam; TIGR02937; sigma70-ECF; 1.
DR PANTHER; PTHR30603; RNA POLYMERASE SIGMA FACTOR RPO; 1.
DR PANTHER; PTHR30603:SF47; RNA POLYMERASE SIGMA FACTOR SIGF, CHLOROPLASTIC; 1.
DR Pfam; PF13589; HATPase_c_3; 1.
DR Pfam; PF04542; Sigma70_r2; 1.
DR Pfam; PF04545; Sigma70_r4; 1.
DR PRINTS; PR00046; SIGMA70FCT.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF88946; Sigma2 domain of RNA polymerase sigma factors; 1.
DR SUPFAM; SSF88659; Sigma3 and sigma4 domains of RNA polymerase sigma factors; 1.
DR PROSITE; PS00715; SIGMA70_1; 1.
DR PROSITE; PS00716; SIGMA70_2; 1.
PE 3: Inferred from homology;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|RuleBase:RU362124};
KW Reference proteome {ECO:0000313|Proteomes:UP000033572};
KW Sigma factor {ECO:0000256|ARBA:ARBA00023082,
KW ECO:0000256|RuleBase:RU362124};
KW Transcription {ECO:0000256|ARBA:ARBA00023163,
KW ECO:0000256|RuleBase:RU362124};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015,
KW ECO:0000256|RuleBase:RU362124}.
FT DOMAIN 630..643
FT /note="RNA polymerase sigma-70"
FT /evidence="ECO:0000259|PROSITE:PS00715"
FT DOMAIN 803..829
FT /note="RNA polymerase sigma-70"
FT /evidence="ECO:0000259|PROSITE:PS00716"
FT REGION 829..871
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1020 AA; 111580 MW; BABA372DC0D9AB09 CRC64;
MDDFTTADGS EPERVVLQPD ASVLDALGRG HTLTSALADL IDNSIDAGAG SVSIMFVVKD
SMIRSIRIAD DGCGMTAHQL ADAMTIGRRR QYGSSSLGHF GVGLKGASLS QARVLSVYST
SGHAQPAGMR LAKGQSGNGI IADVIDADAV AAILRLRGVG ASGTLVEWTH LESVSVATTL
QERRRWIERT ILQVRDELGL TFHRLLADGR VRIELVEMDE DSGETGAPRR VRPIDPFGFD
RWGINGYPRR LSVQLQGGVV IHADLFVLAP GVESGLIGRS RREAQGLYIY RNGRLLQSGG
WGGFRSDLPP DLQLARIAID LAEDALDAFV INPEKRGVIL RPSIVQGLER AVTDGVTLRA
FWDACRDAWT QSKRREIRAR PFAQLGEGVP SALSGIVEQT VGVREGDDAA VSFDWKLLDH
EQLFVFDPPT GIIWLNERHR TRLEQDEGNL SLIKTSLFFL LEPHAGKERL AATTAERLDA
MQAGMAANVI PQREAQEVAR VDLPIIGGDP KLPRAVVERA DPDEPLADPR VAHVHVSGEG
LDDFMRGVRK SALLEAEEEV ALGAAIEAGL FARERLLQQH GGRVFDQETL DLAFVERAGK
RAQDRMVLSN VRLVISIARK YQYNGLELGD LIQEGILGLI HAVKKFDYAQ GTKFSTYGTW
WIRQAITRAL ADRGRMIRFP VHVVEKLPEI KQQWNESEGS ATERLHAVAE QRAESVGAIR
GIVNNLYEPL SLDSTIAVKV DSGSWMPIPV VDVLTESDAF GPEEWAERFD KVRRVNDLLS
ALSDREQAVM RKRFGMEDGV PQTLDQIGDA FGVTRERIRQ IEKKAIESMR RSAGILPQES
EARGARQSRD KGAAPGRAAA PRAVKGEAGE EAPVRFDPAA EAAPAAEHTA VPWPTMVRVF
GLYSDGWSIA RIADAVDTAA DDIAAALARC VFDLDEGDVR PLASEHARTA LGVPERDRIH
QLLTQGLTLS AAGDLTDSPL LLMAWSILDS DERPRLTRRM LSAMRPQEDA AHLARASELS
//
