ID A0A0F0L8E1_9MICO Unreviewed; 991 AA.
AC A0A0F0L8E1;
DT 24-JUN-2015, integrated into UniProtKB/TrEMBL.
DT 24-JUN-2015, sequence version 1.
DT 27-MAR-2024, entry version 37.
DE SubName: Full=Glutamate-ammonia-ligase adenylyltransferase {ECO:0000313|EMBL:KJL27806.1};
DE EC=2.7.7.42 {ECO:0000313|EMBL:KJL27806.1};
GN Name=glnE {ECO:0000313|EMBL:KJL27806.1};
GN ORFNames=RS83_02861 {ECO:0000313|EMBL:KJL27806.1};
OS Microbacterium oxydans.
OC Bacteria; Actinomycetota; Actinomycetes; Micrococcales; Microbacteriaceae;
OC Microbacterium.
OX NCBI_TaxID=82380 {ECO:0000313|EMBL:KJL27806.1, ECO:0000313|Proteomes:UP000033640};
RN [1] {ECO:0000313|EMBL:KJL27806.1, ECO:0000313|Proteomes:UP000033640}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BEL4b {ECO:0000313|EMBL:KJL27806.1,
RC ECO:0000313|Proteomes:UP000033640};
RA Corretto E.;
RT "Draft genome sequences of ten Microbacterium spp. with emphasis on heavy
RT metal contaminated environments.";
RL Submitted (FEB-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KJL27806.1}.
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DR EMBL; JYIW01000026; KJL27806.1; -; Genomic_DNA.
DR RefSeq; WP_045280166.1; NZ_JYIW01000026.1.
DR AlphaFoldDB; A0A0F0L8E1; -.
DR PATRIC; fig|82380.11.peg.2900; -.
DR OrthoDB; 9759366at2; -.
DR Proteomes; UP000033640; Unassembled WGS sequence.
DR GO; GO:0008882; F:[glutamate-ammonia-ligase] adenylyltransferase activity; IEA:UniProtKB-EC.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016874; F:ligase activity; IEA:UniProtKB-KW.
DR CDD; cd05401; NT_GlnE_GlnD_like; 2.
DR Gene3D; 3.30.460.10; Beta Polymerase, domain 2; 2.
DR Gene3D; 1.20.120.330; Nucleotidyltransferases domain 2; 2.
DR InterPro; IPR023057; GlnE.
DR InterPro; IPR005190; GlnE_rpt_dom.
DR InterPro; IPR043519; NT_sf.
DR InterPro; IPR013546; PII_UdlTrfase/GS_AdlTrfase.
DR PANTHER; PTHR30621:SF0; BIFUNCTIONAL GLUTAMINE SYNTHETASE ADENYLYLTRANSFERASE_ADENYLYL-REMOVING ENZYME; 1.
DR PANTHER; PTHR30621; GLUTAMINE SYNTHETASE ADENYLYLTRANSFERASE; 1.
DR Pfam; PF08335; GlnD_UR_UTase; 2.
DR Pfam; PF03710; GlnE; 2.
DR SUPFAM; SSF81301; Nucleotidyltransferase; 2.
DR SUPFAM; SSF81593; Nucleotidyltransferase substrate binding subunit/domain; 2.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Ligase {ECO:0000313|EMBL:KJL27806.1};
KW Magnesium {ECO:0000256|ARBA:ARBA00022842};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Nucleotidyltransferase {ECO:0000256|ARBA:ARBA00022695,
KW ECO:0000313|EMBL:KJL27806.1}; Transferase {ECO:0000313|EMBL:KJL27806.1}.
FT DOMAIN 83..326
FT /note="Glutamate-ammonia ligase adenylyltransferase
FT repeated"
FT /evidence="ECO:0000259|Pfam:PF03710"
FT DOMAIN 353..489
FT /note="PII-uridylyltransferase/Glutamine-synthetase
FT adenylyltransferase"
FT /evidence="ECO:0000259|Pfam:PF08335"
FT DOMAIN 594..825
FT /note="Glutamate-ammonia ligase adenylyltransferase
FT repeated"
FT /evidence="ECO:0000259|Pfam:PF03710"
FT DOMAIN 863..989
FT /note="PII-uridylyltransferase/Glutamine-synthetase
FT adenylyltransferase"
FT /evidence="ECO:0000259|Pfam:PF08335"
SQ SEQUENCE 991 AA; 108410 MW; BF78504ABA01A579 CRC64;
MARPDDSVSL SALARLGFAE LSEAAASLSE LADILDSPRA EILDAAGVAD PDAAVRGLLR
VARRDAAPVK ALLDDPITRH RAWRVFGASE GLADFFLRHP EELPALAGSL EQLPSSIDLR
ARLLSSIDSV AGFAASGEDA AVVALRVAYR SSLAVIAAYD VTHADPVSVV GDVSAALADA
AGAALEAALA VARTRVSDTY PRDEVAATRL AIIGMGKSGA RELNYVSDVD VIFVGGTVDE
EVVSEARSID IATRLARETM RGLSGIEVEP PLWEVDAALR PEGKQGALVR SLGSHLAYYD
RWAKSWEFQA LLKARPLAGD DELGAEYIAA VQPKIWSSAA RQDFVDSVQR MRQRVMEHID
PEDAPYQIKL GSGGLRDIEF TVQLLQLVHG LTDESLRTRG TLESLDALVE GGYIGRAEAA
AFAKDYCVLR VMEHRLQLRE LSRTHLMPRT PAGLRVLARA TGLAETGDGI WARWESVRRE
VRDIHTRLFY RPLLSAVAAL PEEERTLSAA QAHDRLAAIG FRDPTGALRH IGALTTGLSR
KATIQRHLMP IMVRWFADGS DPDYGLIAFR RISERLGDTP WFLRMLRDSS GAAESLTRIL
SSSRYIGELM EWIPESVAWL DKRESLRPRG AAALDEEARA IQTRHDSVGD ALRAVRANRR
RELLRTAMGA VLDVLTIEEI ATALTEITES TIQAALRAVF REVVPAEDAA LDFAVIGMGR
FGGAELGFGS DADILYVYDA NGVEPQRAQE LATQIVTRLR EHLTDHRVPL DLDADLRPEG
RSGPLVRSIE AYTAYYRRWS LSWEAQALLR GRGVAGSAKL IAKFVELADS IRYPETVDQQ
GLREIKRIKA RVEGERLPQG ADPRRHLKLG PGTLSDVEWL VQLLQLQHAH AIPGLRTTST
IAALDSAVGA GLVPEEAAER LAEAWRLASR LRSAITLLTG QTSDVLPADR RELDAIARLL
GYPDRSATEL DEDYLGVTRR SRKAFEQLFY G
//
