ID A0A0F2C7Q7_9MICO Unreviewed; 375 AA.
AC A0A0F2C7Q7;
DT 24-JUN-2015, integrated into UniProtKB/TrEMBL.
DT 24-JUN-2015, sequence version 1.
DT 24-JAN-2024, entry version 36.
DE SubName: Full=Bifunctional uroporphyrinogen-III synthetase/response regulator domain protein {ECO:0000313|EMBL:KJQ54748.1};
GN ORFNames=RS85_01482 {ECO:0000313|EMBL:KJQ54748.1};
OS Microbacterium sp. SA39.
OC Bacteria; Actinomycetota; Actinomycetes; Micrococcales; Microbacteriaceae;
OC Microbacterium.
OX NCBI_TaxID=1263625 {ECO:0000313|EMBL:KJQ54748.1, ECO:0000313|Proteomes:UP000033425};
RN [1] {ECO:0000313|EMBL:KJQ54748.1, ECO:0000313|Proteomes:UP000033425}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SA39 {ECO:0000313|EMBL:KJQ54748.1,
RC ECO:0000313|Proteomes:UP000033425};
RA Corretto E., Antonielli L., Sessitsch A., Kidd P., Weyens N., Brader G.;
RT "Draft genome sequences of ten Microbacterium spp. with emphasis on heavy
RT metal contaminated environments.";
RL Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KJQ54748.1}.
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DR EMBL; JXRU01000031; KJQ54748.1; -; Genomic_DNA.
DR RefSeq; WP_046012779.1; NZ_JXRU01000031.1.
DR AlphaFoldDB; A0A0F2C7Q7; -.
DR STRING; 1263625.RS85_01482; -.
DR PATRIC; fig|1263625.4.peg.1490; -.
DR OrthoDB; 213853at2; -.
DR Proteomes; UP000033425; Unassembled WGS sequence.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0004852; F:uroporphyrinogen-III synthase activity; IEA:InterPro.
DR GO; GO:0000160; P:phosphorelay signal transduction system; IEA:InterPro.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR GO; GO:0006780; P:uroporphyrinogen III biosynthetic process; IEA:InterPro.
DR CDD; cd06578; HemD; 1.
DR CDD; cd00383; trans_reg_C; 1.
DR Gene3D; 3.40.50.10090; -; 2.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR036108; 4pyrrol_syn_uPrphyn_synt_sf.
DR InterPro; IPR003754; 4pyrrol_synth_uPrphyn_synth.
DR InterPro; IPR001867; OmpR/PhoB-type_DNA-bd.
DR InterPro; IPR016032; Sig_transdc_resp-reg_C-effctor.
DR InterPro; IPR039793; UROS/Hem4.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR PANTHER; PTHR40082; BLR5956 PROTEIN; 1.
DR PANTHER; PTHR40082:SF1; BLR5956 PROTEIN; 1.
DR Pfam; PF02602; HEM4; 1.
DR Pfam; PF00486; Trans_reg_C; 1.
DR SMART; SM00862; Trans_reg_C; 1.
DR SUPFAM; SSF46894; C-terminal effector domain of the bipartite response regulators; 1.
DR SUPFAM; SSF69618; HemD-like; 1.
DR PROSITE; PS51755; OMPR_PHOB; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|PROSITE-ProRule:PRU01091};
KW Reference proteome {ECO:0000313|Proteomes:UP000033425}.
FT DOMAIN 279..372
FT /note="OmpR/PhoB-type"
FT /evidence="ECO:0000259|PROSITE:PS51755"
FT DNA_BIND 279..372
FT /note="OmpR/PhoB-type"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01091"
SQ SEQUENCE 375 AA; 38809 MW; E24653EBF07963AC CRC64;
MTNTPTLDSA LAGCTIIVAA DRRSVDLATA LERRGAQVHR APALSIVANA DDVELMRRTE
QLIAAPPDIV VVTTGVGFRG WMDAAHEHGL DEGIVAALRG AHFVARGPKA HGAIQQAGFA
ADWVAESETS AEVGEYLLAS GISGKRIVVQ HHGAGSDGLD ELLAEAGAEV VSVTVYRWGP
PPDPEVVRRS ARQAGAGEAD AVLFTSAPGA ASWLAVAEEA GVLDDIRRRA AAGRLLLAAV
GPITAGPLVA AGLPTTIADR GRLGSLARCV IAHFGGGRAP SVETDAGRLE VRSGGVLLDA
RFLPLSRTAA GLIEALFMAG GRVLSRAEIA RVLPGGDRNG HAVEVAVARL RESLCGAELV
QTVVKRGYRL AVLEY
//
