ID A0A0F2E1T1_STROR Unreviewed; 367 AA.
AC A0A0F2E1T1;
DT 24-JUN-2015, integrated into UniProtKB/TrEMBL.
DT 24-JUN-2015, sequence version 1.
DT 24-JAN-2024, entry version 33.
DE SubName: Full=Prephenate dehydrogenase {ECO:0000313|EMBL:KJQ77238.1};
DE EC=1.3.1.12 {ECO:0000313|EMBL:KJQ77238.1};
GN Name=tyrA {ECO:0000313|EMBL:KJQ77238.1};
GN ORFNames=B7729_06285 {ECO:0000313|EMBL:ORO37610.1}, TZ95_01088
GN {ECO:0000313|EMBL:KJQ77238.1};
OS Streptococcus oralis subsp. tigurinus.
OC Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
OC Streptococcus.
OX NCBI_TaxID=1077464 {ECO:0000313|EMBL:KJQ77238.1, ECO:0000313|Proteomes:UP000033377};
RN [1] {ECO:0000313|EMBL:KJQ77238.1, ECO:0000313|Proteomes:UP000033377}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=UC5873 {ECO:0000313|EMBL:KJQ77238.1,
RC ECO:0000313|Proteomes:UP000033377};
RA Haase E.M.;
RT "Evolution of amylase-binding proteins of oral streptococcal species.";
RL Submitted (FEB-2015) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:ORO37610.1, ECO:0000313|Proteomes:UP000193538}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=OD_348934_12 {ECO:0000313|EMBL:ORO37610.1,
RC ECO:0000313|Proteomes:UP000193538};
RX PubMed=27325438; DOI=10.1007/s10096-016-2700-2;
RA Rasmussen L.H., Dargis R., Hojholt K., Christensen J.J., Skovgaard O.,
RA Justesen U.S., Rosenvinge F.S., Moser C., Lukjancenko O., Rasmussen S.,
RA Nielsen X.C.;
RT "Whole genome sequencing as a tool for phylogenetic analysis of clinical
RT strains of Mitis group streptococci.";
RL Eur. J. Clin. Microbiol. Infect. Dis. 35:1615-1625(2016).
RN [3] {ECO:0000313|EMBL:ORO37610.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=OD_348934_12 {ECO:0000313|EMBL:ORO37610.1};
RA Afonso C.L., Miller P.J., Scott M.A., Spackman E., Goraichik I.,
RA Dimitrov K.M., Suarez D.L., Swayne D.E.;
RL Submitted (APR-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- PATHWAY: Amino-acid biosynthesis. {ECO:0000256|ARBA:ARBA00029440}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KJQ77238.1}.
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DR EMBL; JYGU01000006; KJQ77238.1; -; Genomic_DNA.
DR EMBL; NCUC01000014; ORO37610.1; -; Genomic_DNA.
DR RefSeq; WP_045617378.1; NZ_NCUC01000014.1.
DR AlphaFoldDB; A0A0F2E1T1; -.
DR PATRIC; fig|28037.217.peg.1061; -.
DR OrthoDB; 9802008at2; -.
DR Proteomes; UP000033377; Unassembled WGS sequence.
DR Proteomes; UP000193538; Unassembled WGS sequence.
DR GO; GO:0070403; F:NAD+ binding; IEA:InterPro.
DR GO; GO:0008977; F:prephenate dehydrogenase (NAD+) activity; IEA:UniProtKB-EC.
DR GO; GO:0004665; F:prephenate dehydrogenase (NADP+) activity; IEA:InterPro.
DR GO; GO:0006571; P:tyrosine biosynthetic process; IEA:InterPro.
DR Gene3D; 1.10.3660.10; 6-phosphogluconate dehydrogenase C-terminal like domain; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR008927; 6-PGluconate_DH-like_C_sf.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR046825; PDH_C.
DR InterPro; IPR046826; PDH_N.
DR InterPro; IPR003099; Prephen_DH.
DR PANTHER; PTHR21363; PREPHENATE DEHYDROGENASE; 1.
DR PANTHER; PTHR21363:SF0; PREPHENATE DEHYDROGENASE [NADP(+)]; 1.
DR Pfam; PF20463; PDH_C; 1.
DR Pfam; PF02153; PDH_N; 1.
DR SUPFAM; SSF48179; 6-phosphogluconate dehydrogenase C-terminal domain-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR PROSITE; PS51176; PDH_ADH; 1.
PE 4: Predicted;
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002,
KW ECO:0000313|EMBL:KJQ77238.1}.
FT DOMAIN 3..293
FT /note="Prephenate/arogenate dehydrogenase"
FT /evidence="ECO:0000259|PROSITE:PS51176"
SQ SEQUENCE 367 AA; 40998 MW; 3BE675F00DE1C07E CRC64;
MAKTVYIAGL GLIGASMALG IKRDHPDYEI LGYNRSQASR DIALKEGMID RATDDFASFA
PLADVIILTL PIKQTIAFIQ ELAGLNLKEG VIISDAGSTK AAIVEVAEEY LAGKSIRFVG
AHPMAGSHKT GAASADVNLF ENAYYIFTPS SLTIPETLSE MKDLLSGLHA RFIEIDAKEH
DQVTSQISHF PHILASGLME QTAVYAQEHE MTRRFAAGGF RDMTRIAESE PGMWTSILLS
NRETILERIE DFKERLDEIG QAISKGEEER IWDFFNQARE QRQAMEIHKR GGVDSSYDLY
VDVPDEEDVI LRILELLRGT SLVNIHINEE NREDVHGILQ ISFKNAQDLE RAERLISENT
DYTVVIK
//
