ID A0A0F2LR47_SPOSC Unreviewed; 843 AA.
AC A0A0F2LR47;
DT 24-JUN-2015, integrated into UniProtKB/TrEMBL.
DT 24-JUN-2015, sequence version 1.
DT 27-MAR-2024, entry version 33.
DE RecName: Full=Transcription initiation factor TFIID subunit 12 {ECO:0000256|ARBA:ARBA00017484};
GN ORFNames=SPSK_00428 {ECO:0000313|EMBL:KJR80008.1};
OS Sporothrix schenckii 1099-18.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Sordariomycetidae; Ophiostomatales; Ophiostomataceae; Sporothrix.
OX NCBI_TaxID=1397361 {ECO:0000313|EMBL:KJR80008.1, ECO:0000313|Proteomes:UP000033710};
RN [1] {ECO:0000313|EMBL:KJR80008.1, ECO:0000313|Proteomes:UP000033710}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=1099-18 {ECO:0000313|EMBL:KJR80008.1,
RC ECO:0000313|Proteomes:UP000033710};
RX PubMed=25351875; DOI=10.1186/1471-2164-15-943;
RA Teixeira M.M., de Almeida L.G., Kubitschek-Barreira P., Alves F.L.,
RA Kioshima E.S., Abadio A.K., Fernandes L., Derengowski L.S., Ferreira K.S.,
RA Souza R.C., Ruiz J.C., de Andrade N.C., Paes H.C., Nicola A.M.,
RA Albuquerque P., Gerber A.L., Martins V.P., Peconick L.D., Neto A.V.,
RA Chaucanez C.B., Silva P.A., Cunha O.L., de Oliveira F.F., dos Santos T.C.,
RA Barros A.L., Soares M.A., de Oliveira L.M., Marini M.M.,
RA Villalobos-Duno H., Cunha M.M., de Hoog S., da Silveira J.F., Henrissat B.,
RA Nino-Vega G.A., Cisalpino P.S., Mora-Montes H.M., Almeida S.R.,
RA Stajich J.E., Lopes-Bezerra L.M., Vasconcelos A.T., Felipe M.S.;
RT "Comparative genomics of the major fungal agents of human and animal
RT Sporotrichosis: Sporothrix schenckii and Sporothrix brasiliensis.";
RL BMC Genomics 15:943-943(2014).
RN [2] {ECO:0000313|EMBL:KJR80008.1, ECO:0000313|Proteomes:UP000033710}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=1099-18 {ECO:0000313|EMBL:KJR80008.1,
RC ECO:0000313|Proteomes:UP000033710};
RX PubMed=25480940;
RA Teixeira Mde M., Rodrigues A.M., Tsui C.K., de Almeida L.G.,
RA Van Diepeningen A.D., van den Ende B.G., Fernandes G.F., Kano R.,
RA Hamelin R.C., Lopes-Bezerra L.M., Vasconcelos A.T., de Hoog S.,
RA de Camargo Z.P., Felipe M.S.;
RT "Asexual propagation of a virulent clone complex in a human and feline
RT outbreak of sporotrichosis.";
RL Eukaryot. Cell 14:158-169(2015).
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the TAF12 family.
CC {ECO:0000256|ARBA:ARBA00007530}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KJR80008.1}.
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DR EMBL; AXCR01000012; KJR80008.1; -; Genomic_DNA.
DR RefSeq; XP_016582684.1; XM_016727397.1.
DR AlphaFoldDB; A0A0F2LR47; -.
DR GeneID; 27662674; -.
DR KEGG; ssck:SPSK_00428; -.
DR VEuPathDB; FungiDB:SPSK_00428; -.
DR OrthoDB; 22237at2759; -.
DR Proteomes; UP000033710; Unassembled WGS sequence.
DR GO; GO:0000124; C:SAGA complex; IEA:InterPro.
DR GO; GO:0046695; C:SLIK (SAGA-like) complex; IEA:InterPro.
DR GO; GO:0005669; C:transcription factor TFIID complex; IEA:InterPro.
DR GO; GO:0046982; F:protein heterodimerization activity; IEA:InterPro.
DR GO; GO:0006352; P:DNA-templated transcription initiation; IEA:InterPro.
DR CDD; cd07981; TAF12; 1.
DR Gene3D; 1.10.20.10; Histone, subunit A; 1.
DR InterPro; IPR009072; Histone-fold.
DR InterPro; IPR037794; TAF12.
DR InterPro; IPR003228; TFIID_TAF12_dom.
DR PANTHER; PTHR12264; TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 12; 1.
DR PANTHER; PTHR12264:SF21; TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 12; 1.
DR Pfam; PF03847; TFIID_20kDa; 1.
DR SUPFAM; SSF47113; Histone-fold; 1.
PE 3: Inferred from homology;
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 727..801
FT /note="Transcription initiation factor TFIID subunit 12"
FT /evidence="ECO:0000259|Pfam:PF03847"
FT REGION 1..55
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 67..86
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 104..152
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 202..249
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 369..408
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 432..545
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 563..618
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..37
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 105..152
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 226..249
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 432..458
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 459..496
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 843 AA; 88308 MW; 38DEEF890BDC53F4 CRC64;
MNQGTPQQTG AGTPGASSVP MQQSSSQQQQ QQPIMYRPEQ MRTIKELTPQ ERGKYENGLR
VLWATLESNP EGSSERETAR RKIQEFTPVL ARKIRERRMA ALQRQQMLLK QQQQQQQQQQ
GQQSPQGDGQ AAAQQMQQAQ SAQGQASNQA QAQAQAQAQA QAQAQAQAQA QAQAQAQAQA
QAQAQAQAQA QQQQLQQQQG QARAASAAAG NAGAAARPGA AGSPPAGPQQ QAQAGAAGPQ
QQQRPQQPTK FSDNVLQNLS LLTYLPPPAL ADKPPEVAAK WQEDVRKKLG MSLTQIEMAR
SNVNKLDASF KMRSANNQIT PEDAKAYKDR RDMLQKLLDD STRFVAAYRK QQEQTKVYMQ
QKMMQQQAAG GAAGGQQQPL STQQAGAAAQ QPAGQQKNAK TEATNMQSSQ ANINGAIEAA
KKESIAAGAR QGTGNTNMAI NSNNNNVAGG ANKPAPGSVQ QTPIPPPVIP AAAMQGAPKQ
PPKPPVQTPV HPPPTPINTA AAAANKAGGP PTAGTPTPAS AAAAASRVPQ TPHVATPVNA
PPRALSHQKA IEEANKRRAA SINNGAVSTP PVASANGATP GSGAATPGGG NNSAATPQQQ
NNQAQNQSMQ QQQAAMNQQQ QQAAAAAAAA AAAANSGAGG QNIPTSATQE AARINSKLGE
SRQNITKQLS EKAAQMPQPV SLGGGLVPGR PTLTGGGGVV GGVLGQAAIA KVPAIQIDGE
GERVLNKKRL DELVRQVCGG TAEGHEGNLL QPEVEEKSVL NLADSFVDNV LHSACRNAKE
RGSKVLEIRD LQLVLERTYN IRIPGYSSDE LRTVRKVQPS MAWITKMSVI QAAKVTSATK
NDP
//
