ID A0A0F2M8X3_SPOSC Unreviewed; 1747 AA.
AC A0A0F2M8X3;
DT 24-JUN-2015, integrated into UniProtKB/TrEMBL.
DT 24-JUN-2015, sequence version 1.
DT 27-MAR-2024, entry version 30.
DE SubName: Full=Membrane-tethered transcription factor {ECO:0000313|EMBL:KJR85529.1};
GN ORFNames=SPSK_08283 {ECO:0000313|EMBL:KJR85529.1};
OS Sporothrix schenckii 1099-18.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Sordariomycetidae; Ophiostomatales; Ophiostomataceae; Sporothrix.
OX NCBI_TaxID=1397361 {ECO:0000313|EMBL:KJR85529.1, ECO:0000313|Proteomes:UP000033710};
RN [1] {ECO:0000313|EMBL:KJR85529.1, ECO:0000313|Proteomes:UP000033710}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=1099-18 {ECO:0000313|EMBL:KJR85529.1,
RC ECO:0000313|Proteomes:UP000033710};
RX PubMed=25351875; DOI=10.1186/1471-2164-15-943;
RA Teixeira M.M., de Almeida L.G., Kubitschek-Barreira P., Alves F.L.,
RA Kioshima E.S., Abadio A.K., Fernandes L., Derengowski L.S., Ferreira K.S.,
RA Souza R.C., Ruiz J.C., de Andrade N.C., Paes H.C., Nicola A.M.,
RA Albuquerque P., Gerber A.L., Martins V.P., Peconick L.D., Neto A.V.,
RA Chaucanez C.B., Silva P.A., Cunha O.L., de Oliveira F.F., dos Santos T.C.,
RA Barros A.L., Soares M.A., de Oliveira L.M., Marini M.M.,
RA Villalobos-Duno H., Cunha M.M., de Hoog S., da Silveira J.F., Henrissat B.,
RA Nino-Vega G.A., Cisalpino P.S., Mora-Montes H.M., Almeida S.R.,
RA Stajich J.E., Lopes-Bezerra L.M., Vasconcelos A.T., Felipe M.S.;
RT "Comparative genomics of the major fungal agents of human and animal
RT Sporotrichosis: Sporothrix schenckii and Sporothrix brasiliensis.";
RL BMC Genomics 15:943-943(2014).
RN [2] {ECO:0000313|EMBL:KJR85529.1, ECO:0000313|Proteomes:UP000033710}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=1099-18 {ECO:0000313|EMBL:KJR85529.1,
RC ECO:0000313|Proteomes:UP000033710};
RX PubMed=25480940;
RA Teixeira Mde M., Rodrigues A.M., Tsui C.K., de Almeida L.G.,
RA Van Diepeningen A.D., van den Ende B.G., Fernandes G.F., Kano R.,
RA Hamelin R.C., Lopes-Bezerra L.M., Vasconcelos A.T., de Hoog S.,
RA de Camargo Z.P., Felipe M.S.;
RT "Asexual propagation of a virulent clone complex in a human and feline
RT outbreak of sporotrichosis.";
RL Eukaryot. Cell 14:158-169(2015).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KJR85529.1}.
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DR EMBL; AXCR01000007; KJR85529.1; -; Genomic_DNA.
DR RefSeq; XP_016588205.1; XM_016734887.1.
DR GeneID; 27670164; -.
DR KEGG; ssck:SPSK_08283; -.
DR VEuPathDB; FungiDB:SPSK_08283; -.
DR OrthoDB; 2901153at2759; -.
DR Proteomes; UP000033710; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR CDD; cd00102; IPT; 1.
DR Gene3D; 1.25.40.20; Ankyrin repeat-containing domain; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR InterPro; IPR002110; Ankyrin_rpt.
DR InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR014756; Ig_E-set.
DR InterPro; IPR002909; IPT_dom.
DR PANTHER; PTHR24148; ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 39 HOMOLOG-RELATED; 1.
DR PANTHER; PTHR24148:SF77; IPT_TIG DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF12796; Ank_2; 1.
DR Pfam; PF01833; TIG; 1.
DR SMART; SM00248; ANK; 2.
DR SMART; SM00429; IPT; 1.
DR SUPFAM; SSF48403; Ankyrin repeat; 1.
DR SUPFAM; SSF81296; E set domains; 1.
DR PROSITE; PS50297; ANK_REP_REGION; 2.
DR PROSITE; PS50088; ANK_REPEAT; 2.
PE 4: Predicted;
KW ANK repeat {ECO:0000256|PROSITE-ProRule:PRU00023};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 1653..1671
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 1026..1117
FT /note="IPT/TIG"
FT /evidence="ECO:0000259|SMART:SM00429"
FT REPEAT 1222..1254
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 1255..1287
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REGION 47..183
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 213..252
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 265..301
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 537..564
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 686..754
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 798..879
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 957..976
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1154..1176
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1342..1394
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1504..1524
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1694..1718
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 47..68
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 89..132
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 140..161
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 168..182
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 228..243
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 287..301
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 712..753
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 835..879
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1347..1364
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1694..1709
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1747 AA; 184653 MW; 8A3DCA9AF541D3EB CRC64;
MSDQDTSFEA LAASPGDYAV HSEWMGDSPP ALTVDFIQNP HNQIHHIHQV GGNQNPQAHK
SRGFDSTTAG GPGSGKPGIG KDRLLADDSS LALSQQQSVS SPESLLSSFQ DSSSDISSSK
QTSLTALSSL AGGTPAKKSR GRSSKGSTIT KASSNPSRPA GTAVPNPAAR LHQQQTTSVG
DDIMMTDEGL RAGDDLGDST QQNWSFRDYL RLDDDQDDDE DDHNQSMNTE SDGFATIDPK
SIQNTPGFGG AEDALNQEAA AGLRSSLKTE PTVGSDLSPY SGGPSPLEFV SATSSPTPDD
LTIPAFNTPQ LFSSAVAMFG QAPTDSATEQ RRKGHNKAAS SMNNLNTAAS REVSPVSNFV
FGQGPSPTAF MQSSQSPIDS NDFRFGFLGN GGADPIQMAS NFLFPESMPA SPTSVWQGNV
PQQQQLLNNV AAQMPVFQQG PAAATTAAAP LNNQRQPLRF SVGIEPHKSR VETQIPVTIL
LSSLPPDVTK LHLPPHTISK PKLLAKNAPE HSPDTLELHT MVVCTSAMAN EANRQRALER
AAASTYGPQA RPSDDASGED GDDCRPADGG EVWICSGCIQ RERKRANRKK SKKPEDDEGW
SRDEHRRIII FNTNEIKDWQ HPTAATNLGP QSENAAIVIP MRITCYCRHH GEKAGFQVIF
TLKDYRGQVL AQTISRSIMI TDDHKTPTAA SAGSASAAPS VVDGDASAGD VADTSKPSSA
TTVAPASGTK AATKTGKSNR TSQSSSDPSA LKRGSVTFSA PEIDKASSSN ANSYTSAAVA
AAAAASSSVA AMARALSRPA SPDGLKGHSA KKRKSSAGVP GAPGAAKVPS GLAMTRIETS
PQPQQPTQQH VSDSGSRRAA SSTSPVAQFS NNSTFLSPPS GFVPDTMAAA VDMALRAGGS
GDPDIDSLAG IVPMNADPMP TGPLTPNSHT DQTAAYINGN RSGSFDNIGL SQTPMFSAPT
STHPSRAPSP NGLRGPIHMF QQQLFQQQQQ QLQQQLNQAQ FSQQFQNGLF SLPMSLPQTD
TTPTSQPVVH KIIPAEGPKS GGIEVTILGS SFYQGLDVMF GDQRATTTTF WGESSLVCLV
PPSSIAGHVP VTLRQSNQRG SAQPFAANQQ RITFKYLDDD EQQLLRAALT VLSRKMTGKI
EDAQDVARRI IGSETSTWGT SGGGTSGGSS AGSTRGVSGN VADVASSTGG PNFETHLLKV
LELIDLDDSS NQTRLNMQRR TTGHSMLHLA CVLGMHRFVA GLLARGANPD VRDNGGYTPL
HLAALNNQPE IVRRLIHAGA DPTMRTLSGL TASEVTASRE VLRAIKRFER HARSRSGGSL
HSRTNSAASL RSLWEPMSMS TIRRRASGAG EEVETGDSED SSRAEVDSSS YAASGDDEAS
SEQEGDVEWL DMRPGSRVMS RGSLSIHGRH GVRDTSPDPL AASNVAADAA ARGANVPAAL
ASPAAAAMSA FKEQLSAHFQ QLIAQIPQIP NNPLPDYYQA YLNSAAFQRI SSLVPNINIS
GAMGSRPNSS GNSDAGGAPG TKEFEGRWWD LSSRMTGSAP PPAYEEIFPQ KSGAMDTKQA
TAAAAAAEAE ADTKCAALYD NQQVEELNQQ ATAAKTTATT QIEDNGGEID DEEECLASTP
VLQIGRKHQI TKEQQENFRR VHKEKRKGLS SDTFLYTVWI PILLGVLLLW LSGARAWDFF
PSVTFNVPYA TSLSNPIRPT STNADNGNKD KDNVAGEKQI LPDPPAVAAI PNNDAQDVLG
GIHGIVV
//
