ID A0A0F2MDU1_SPOSC Unreviewed; 1641 AA.
AC A0A0F2MDU1;
DT 24-JUN-2015, integrated into UniProtKB/TrEMBL.
DT 24-JUN-2015, sequence version 1.
DT 27-MAR-2024, entry version 32.
DE SubName: Full=LysM domain protein {ECO:0000313|EMBL:KJR87858.1};
GN ORFNames=SPSK_06871 {ECO:0000313|EMBL:KJR87858.1};
OS Sporothrix schenckii 1099-18.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Sordariomycetidae; Ophiostomatales; Ophiostomataceae; Sporothrix.
OX NCBI_TaxID=1397361 {ECO:0000313|EMBL:KJR87858.1, ECO:0000313|Proteomes:UP000033710};
RN [1] {ECO:0000313|EMBL:KJR87858.1, ECO:0000313|Proteomes:UP000033710}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=1099-18 {ECO:0000313|EMBL:KJR87858.1,
RC ECO:0000313|Proteomes:UP000033710};
RX PubMed=25351875; DOI=10.1186/1471-2164-15-943;
RA Teixeira M.M., de Almeida L.G., Kubitschek-Barreira P., Alves F.L.,
RA Kioshima E.S., Abadio A.K., Fernandes L., Derengowski L.S., Ferreira K.S.,
RA Souza R.C., Ruiz J.C., de Andrade N.C., Paes H.C., Nicola A.M.,
RA Albuquerque P., Gerber A.L., Martins V.P., Peconick L.D., Neto A.V.,
RA Chaucanez C.B., Silva P.A., Cunha O.L., de Oliveira F.F., dos Santos T.C.,
RA Barros A.L., Soares M.A., de Oliveira L.M., Marini M.M.,
RA Villalobos-Duno H., Cunha M.M., de Hoog S., da Silveira J.F., Henrissat B.,
RA Nino-Vega G.A., Cisalpino P.S., Mora-Montes H.M., Almeida S.R.,
RA Stajich J.E., Lopes-Bezerra L.M., Vasconcelos A.T., Felipe M.S.;
RT "Comparative genomics of the major fungal agents of human and animal
RT Sporotrichosis: Sporothrix schenckii and Sporothrix brasiliensis.";
RL BMC Genomics 15:943-943(2014).
RN [2] {ECO:0000313|EMBL:KJR87858.1, ECO:0000313|Proteomes:UP000033710}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=1099-18 {ECO:0000313|EMBL:KJR87858.1,
RC ECO:0000313|Proteomes:UP000033710};
RX PubMed=25480940;
RA Teixeira Mde M., Rodrigues A.M., Tsui C.K., de Almeida L.G.,
RA Van Diepeningen A.D., van den Ende B.G., Fernandes G.F., Kano R.,
RA Hamelin R.C., Lopes-Bezerra L.M., Vasconcelos A.T., de Hoog S.,
RA de Camargo Z.P., Felipe M.S.;
RT "Asexual propagation of a virulent clone complex in a human and feline
RT outbreak of sporotrichosis.";
RL Eukaryot. Cell 14:158-169(2015).
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00261}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KJR87858.1}.
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DR EMBL; AXCR01000004; KJR87858.1; -; Genomic_DNA.
DR RefSeq; XP_016590534.1; XM_016733544.1.
DR GeneID; 27668821; -.
DR KEGG; ssck:SPSK_06871; -.
DR VEuPathDB; FungiDB:SPSK_06871; -.
DR OrthoDB; 1753565at2759; -.
DR Proteomes; UP000033710; Unassembled WGS sequence.
DR GO; GO:0008061; F:chitin binding; IEA:UniProtKB-UniRule.
DR GO; GO:0004650; F:polygalacturonase activity; IEA:InterPro.
DR CDD; cd11618; ChtBD1_1; 3.
DR CDD; cd00118; LysM; 2.
DR Gene3D; 3.10.350.10; LysM domain; 2.
DR Gene3D; 2.160.20.10; Single-stranded right-handed beta-helix, Pectin lyase-like; 2.
DR InterPro; IPR001002; Chitin-bd_1.
DR InterPro; IPR036861; Endochitinase-like_sf.
DR InterPro; IPR018392; LysM_dom.
DR InterPro; IPR036779; LysM_dom_sf.
DR InterPro; IPR024535; Pectate_lyase_SF_prot.
DR InterPro; IPR012334; Pectin_lyas_fold.
DR InterPro; IPR011050; Pectin_lyase_fold/virulence.
DR InterPro; IPR039279; QRT3-like.
DR PANTHER; PTHR33928:SF2; PECTATE LYASE SUPERFAMILY PROTEIN DOMAIN-CONTAINING PROTEIN-RELATED; 1.
DR PANTHER; PTHR33928; POLYGALACTURONASE QRT3; 1.
DR Pfam; PF01476; LysM; 2.
DR Pfam; PF12708; Pectate_lyase_3; 2.
DR SMART; SM00257; LysM; 2.
DR SUPFAM; SSF54106; LysM domain; 1.
DR SUPFAM; SSF51126; Pectin lyase-like; 2.
DR SUPFAM; SSF57016; Plant lectins/antimicrobial peptides; 1.
DR PROSITE; PS50941; CHIT_BIND_I_2; 4.
DR PROSITE; PS51782; LYSM; 2.
PE 4: Predicted;
KW Chitin-binding {ECO:0000256|ARBA:ARBA00022669, ECO:0000256|PROSITE-
KW ProRule:PRU00261}; Disulfide bond {ECO:0000256|PROSITE-ProRule:PRU00261};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..22
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 23..1641
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5002455031"
FT DOMAIN 1174..1220
FT /note="LysM"
FT /evidence="ECO:0000259|PROSITE:PS51782"
FT DOMAIN 1226..1272
FT /note="LysM"
FT /evidence="ECO:0000259|PROSITE:PS51782"
FT DOMAIN 1427..1477
FT /note="Chitin-binding type-1"
FT /evidence="ECO:0000259|PROSITE:PS50941"
FT DOMAIN 1481..1531
FT /note="Chitin-binding type-1"
FT /evidence="ECO:0000259|PROSITE:PS50941"
FT DOMAIN 1536..1586
FT /note="Chitin-binding type-1"
FT /evidence="ECO:0000259|PROSITE:PS50941"
FT DOMAIN 1590..1640
FT /note="Chitin-binding type-1"
FT /evidence="ECO:0000259|PROSITE:PS50941"
FT REGION 1398..1430
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT DISULFID 1448..1462
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00261"
FT DISULFID 1502..1516
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00261"
FT DISULFID 1557..1571
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00261"
FT DISULFID 1611..1625
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00261"
SQ SEQUENCE 1641 AA; 169883 MW; A40D2080DF6BE7B0 CRC64;
MLSLAYALFF CALGPLVSLA AASSHHHAHN KLHHRQEHNL HGARDTAIDD AYALVNASLP
AIAAANKLKL QQPRFNTYQF PPAGNASSYG RSNTTVPVIG RRGHLMANGS STSTGSVPPF
AANSNTTSRD YIVSPELAKA ARVVAEGTTN KPAGADYTDR AARLKAEHWG QTSPASGDNA
TSVSDGVEAR AAAASSSFWM ANMAMNGVAP YAAAANYKVW RNVMDYGAKG DGKTDDTVAI
NKAITDGGRC GQTCGSSTAT PAVIYFPSGT YLVSDTLIMY YNTQFLGDPT ARPTLLAAAS
FVGYAVVLTD VYIDGANGAE WYIPQSNFLR SVRNFVIDIT NAPANNYVCG IHWQVAQGTD
LQNIDFYMKD GTTQQGLYME NGSGGFMTDL YFQGGNFGAY LGNQQFTARN LIFSGCLTSI
QVFWDWAWLL QGLTIIGDNT KNGPSVGITI VDGAGGSAGS TGQGVGSMII TDCVFYFVDT
AIKTTLVADN SSSFLLQNSL FVQVPVAVYD TGAAKTLLAG SSTGNVQVAS WGFGNIVSGT
SGTSVFQNGN AITAPVRPAS LLPVGSGNWF TRSAPTYADA SIPATAIVNV KTKGAAGDGA
TDDTAALNQA LAAAANASQI VFFPYGVYVV TDTLHIPLGS RIVGQAWSTI AGRGARFQDA
TNPRAVVQVG RAGDAGTVEI SDMLFSVIGP TAGAVVVEWN VHEDTNSSAK GSAAMWNSHI
RVGGNVGSSL QAATCPMSTS GTPKPACVAA SLLFHLTPAA SAYIENFWVW TADHDLDIAS
QDMINVYTGR GVLIESQGPT WLWGSASEHS VLYQYQFSRA SNLFCSMLQT ESPYFQPSPG
APAPFVPGMF PDDPTFADCA LPIAANSRCA LAWPVRILDS TDIFVYSAGL YSWFQSYAKN
CEIGNNCQDG AMDIQRSENV WIYNLCTKAI VNMVTPLGTA VTVGRLNQNG FLASILGWLE
GATTIVGDRF AGWSVFASGS LVGLGLSSAC EAALYQTVKC DDSARNLLAA DAYLGSTGNK
TLTGLVCEAV CEASIAYVRQ SVAAACAVTP HLPGTNVPFV SVVDRLWSNW NQTCFVDPTT
GTNCNDVIAA FPAAADIAAL PVADLCSYCY TQKLKLMEAS AYSGAYDNTS FAARYAYVAS
HCSLTGVGNF NGTASAVTGT TPVDVTAPVC VSGKHYTVAS GDTCDSIAVA NAASSATLFA
INPVLRDCSK ELTVGAVLCL PQTCDTLWTV QPDDTCQSIG NATGNSMDTL VAYNTMLNRN
CSNLQPAPAS EPSWGATLCV SSPGGAYAGV AASNTSTDGN GGRGNGYAPP YTQPIKPPTG
ATVAKGTNAT LCAAWYVYDA TLLCAQICLT NDISIRVLTL ANPSLHVPTC DADLVRGTAY
CVRPLSEVEL TASSALPSSS TASLTSTSTS ATTSKTPSNT PNPISTDGKC GTASSKNATC
QGSTFGNCCG PSGTCGSTPA FCSGRLGCQP TFGECKPISK DGTCGAASSV DALCLYSSFG
DCCGASGKCG TTTAFCNTDE GCQSNYGTCV ARVSTDGKCG NASSVDATCL GSTFGNCCGS
SGTCGSTPAF CYGRLGCQAK YGNCVPISTD GKCGSASSVG AMCLYSAFGD CCSAAGTCGT
TSAACYLSNG CQATYGTCLA K
//
