ID A0A0F2MF44_SPOSC Unreviewed; 1469 AA.
AC A0A0F2MF44;
DT 24-JUN-2015, integrated into UniProtKB/TrEMBL.
DT 24-JUN-2015, sequence version 1.
DT 27-MAR-2024, entry version 44.
DE RecName: Full=ABC transporter {ECO:0008006|Google:ProtNLM};
GN ORFNames=SPSK_06869 {ECO:0000313|EMBL:KJR87699.1};
OS Sporothrix schenckii 1099-18.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Sordariomycetidae; Ophiostomatales; Ophiostomataceae; Sporothrix.
OX NCBI_TaxID=1397361 {ECO:0000313|EMBL:KJR87699.1, ECO:0000313|Proteomes:UP000033710};
RN [1] {ECO:0000313|EMBL:KJR87699.1, ECO:0000313|Proteomes:UP000033710}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=1099-18 {ECO:0000313|EMBL:KJR87699.1,
RC ECO:0000313|Proteomes:UP000033710};
RX PubMed=25351875; DOI=10.1186/1471-2164-15-943;
RA Teixeira M.M., de Almeida L.G., Kubitschek-Barreira P., Alves F.L.,
RA Kioshima E.S., Abadio A.K., Fernandes L., Derengowski L.S., Ferreira K.S.,
RA Souza R.C., Ruiz J.C., de Andrade N.C., Paes H.C., Nicola A.M.,
RA Albuquerque P., Gerber A.L., Martins V.P., Peconick L.D., Neto A.V.,
RA Chaucanez C.B., Silva P.A., Cunha O.L., de Oliveira F.F., dos Santos T.C.,
RA Barros A.L., Soares M.A., de Oliveira L.M., Marini M.M.,
RA Villalobos-Duno H., Cunha M.M., de Hoog S., da Silveira J.F., Henrissat B.,
RA Nino-Vega G.A., Cisalpino P.S., Mora-Montes H.M., Almeida S.R.,
RA Stajich J.E., Lopes-Bezerra L.M., Vasconcelos A.T., Felipe M.S.;
RT "Comparative genomics of the major fungal agents of human and animal
RT Sporotrichosis: Sporothrix schenckii and Sporothrix brasiliensis.";
RL BMC Genomics 15:943-943(2014).
RN [2] {ECO:0000313|EMBL:KJR87699.1, ECO:0000313|Proteomes:UP000033710}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=1099-18 {ECO:0000313|EMBL:KJR87699.1,
RC ECO:0000313|Proteomes:UP000033710};
RX PubMed=25480940;
RA Teixeira Mde M., Rodrigues A.M., Tsui C.K., de Almeida L.G.,
RA Van Diepeningen A.D., van den Ende B.G., Fernandes G.F., Kano R.,
RA Hamelin R.C., Lopes-Bezerra L.M., Vasconcelos A.T., de Hoog S.,
RA de Camargo Z.P., Felipe M.S.;
RT "Asexual propagation of a virulent clone complex in a human and feline
RT outbreak of sporotrichosis.";
RL Eukaryot. Cell 14:158-169(2015).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KJR87699.1}.
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DR EMBL; AXCR01000004; KJR87699.1; -; Genomic_DNA.
DR RefSeq; XP_016590375.1; XM_016733542.1.
DR GeneID; 27668819; -.
DR KEGG; ssck:SPSK_06869; -.
DR VEuPathDB; FungiDB:SPSK_06869; -.
DR OrthoDB; 2301395at2759; -.
DR Proteomes; UP000033710; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0140359; F:ABC-type transporter activity; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR CDD; cd18579; ABC_6TM_ABCC_D1; 1.
DR CDD; cd18580; ABC_6TM_ABCC_D2; 1.
DR CDD; cd03250; ABCC_MRP_domain1; 1.
DR CDD; cd03244; ABCC_MRP_domain2; 1.
DR Gene3D; 1.20.1560.10; ABC transporter type 1, transmembrane domain; 2.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR011527; ABC1_TM_dom.
DR InterPro; IPR036640; ABC1_TM_sf.
DR InterPro; IPR003439; ABC_transporter-like_ATP-bd.
DR InterPro; IPR017871; ABC_transporter-like_CS.
DR InterPro; IPR044746; ABCC_6TM_D1.
DR InterPro; IPR044726; ABCC_6TM_D2.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR24223:SF399; ABC TRANSPORTER ATNG; 1.
DR PANTHER; PTHR24223; ATP-BINDING CASSETTE SUB-FAMILY C; 1.
DR Pfam; PF00664; ABC_membrane; 2.
DR Pfam; PF00005; ABC_tran; 2.
DR SMART; SM00382; AAA; 2.
DR SUPFAM; SSF90123; ABC transporter transmembrane region; 2.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR PROSITE; PS50929; ABC_TM1F; 2.
DR PROSITE; PS00211; ABC_TRANSPORTER_1; 2.
DR PROSITE; PS50893; ABC_TRANSPORTER_2; 2.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 33..54
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 66..87
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 93..115
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 127..145
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 157..174
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 279..300
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 312..335
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 388..407
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 413..431
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 494..518
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 538..563
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 911..937
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 957..987
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1059..1076
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1136..1163
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1175..1197
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 283..558
FT /note="ABC transmembrane type-1"
FT /evidence="ECO:0000259|PROSITE:PS50929"
FT DOMAIN 616..844
FT /note="ABC transporter"
FT /evidence="ECO:0000259|PROSITE:PS50893"
FT DOMAIN 922..1202
FT /note="ABC transmembrane type-1"
FT /evidence="ECO:0000259|PROSITE:PS50929"
FT DOMAIN 1237..1466
FT /note="ABC transporter"
FT /evidence="ECO:0000259|PROSITE:PS50893"
FT REGION 880..900
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1469 AA; 161884 MW; 65D1B75D56160F00 CRC64;
MVRCANDGSF GPVLTPEPDC YSFDFTLTFE DCILSIAPCS IALLLAIVRI YYLLKRNALV
RWPLLLALKL LLFVALLGVQ LGIAVLLGTN RGFHTHTTLA SSVVSLCTTV ALTVLSDLEH
VRSVRPSYLI QSFLFISIFC DLPRIRTQWM LPDNATVAPI FSAAFGLKVL LMFVESIHKY
SHSTLADDKI SPEEIQGVFG DTLFTWLNPL FFEGYKRNLT MDDLYPVDNG LRGQTLYDRL
QSHWLKADIH LHNVANYKRK HCLTYATFRT FTPELAMAFV PRVGLMGLSL SQPYLVSAAI
NYIDNADRPK SYGYGLIGAY AVTYIGIALT TRWYMHIAFR TMAKIRGALV TIIYKNMLAI
RAETGNSSAA LSLMSTDVDR ITFTTFNIVD LAPSVVQLGI ALGILGTELG GSSVAPIILC
LICGIIAARL GKMIPPRQRR WMAAIQKRVG ITSDIVGSMK GVKVAGLNEK AEQQIQGLRD
YEIDQSTAMR KIQVWNLLLG IAPSLLMSAV TFAVYAIVQK VSGDSQFGVA RAFTALSVLN
VLIAPVMTIT SSWTNLATAL ACLDRIQAFL MQEKREDYRI LLPRSDSGSF TTHDSAMLGA
DNASEKSASK DKQPLIKVRE GTFGWKADAP PVLKDVDIDI MPGELTLVIG PVASGKSTLL
KALIGECRKF KGAVEFTIPE EVAYCDQDAW LLNRSIKENV LAYEPYNEEF YEQVIHACQL
VEDIEQFPKR DDTTIGSKGV SLSGGQKQRV ALARAVYNRK PIVILDDILK GLDADTYSKC
FTATLGPEGL LRKNRTSVVL ATHNTQLLPH ADQIIVLDEG GRVTERGSFD HLNSSDGFVA
ALGLKKSAMD AAAIRDALDV EIELKEKEAI IERIASAKAM GRKPPGAGGP PDAVPSDNAS
RGKRNADAMF SYLRSLGGTA FALYAIFTLC DIGFRTAQPV WLNVWTAANE EHPDSRVGYY
VGIYVLFGVL NVLFMVAEFW TFLIIIVPHS AKVLHRKILV AAMHAPLAYF VATDAGEIVN
RFSQDMTLVD MQLPFSFMMC YGQLISAVSQ IILTCVASGY LGIIVPVLLV VLYCVQKFYL
RTSRQMRLLD LEAKSPLYSD FIASFSGLTA LRAYGWTKDA ENESLRRLNE SQKPYYLLYC
IQRWLSLVLN LIVAAMAVIV IGLAVGLRSQ ISPGLLGVAL TSVMGIGMTL SMLIQMWTQL
ETSLGAITRV NEFANDTPRE DDGPDMPPPQ WPSRGAISVQ HLEAKYGDRV VLEDINLEIQ
PGEKVAICGR SGSGKSTLIS LLLRLYSPSQ GQIEIDGIET GRLNLNALRE SLVALPQDPM
FLAGTVRYNL DPLGKATDDE LLAVLDKTNL KKIIDDKGGL DADLDTDWLS AGQRQLFCLA
RALTRKSRVL LLDEATSSLD RETEAFVDKL VQEDFAGWTA IVVAHRLRTV ADFDKVLVLQ
EGRAMEYDSP KALLARDSLF KTLWDLQEA
//
