ID   A0A0F2MJA5_SPOSC        Unreviewed;       464 AA.
AC   A0A0F2MJA5;
DT   24-JUN-2015, integrated into UniProtKB/TrEMBL.
DT   24-JUN-2015, sequence version 1.
DT   27-MAR-2024, entry version 27.
DE   SubName: Full=Ubiquitin-conjugating enzyme E2 Z {ECO:0000313|EMBL:KJR89139.1};
GN   ORFNames=SPSK_06154 {ECO:0000313|EMBL:KJR89139.1};
OS   Sporothrix schenckii 1099-18.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC   Sordariomycetidae; Ophiostomatales; Ophiostomataceae; Sporothrix.
OX   NCBI_TaxID=1397361 {ECO:0000313|EMBL:KJR89139.1, ECO:0000313|Proteomes:UP000033710};
RN   [1] {ECO:0000313|EMBL:KJR89139.1, ECO:0000313|Proteomes:UP000033710}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=1099-18 {ECO:0000313|EMBL:KJR89139.1,
RC   ECO:0000313|Proteomes:UP000033710};
RX   PubMed=25351875; DOI=10.1186/1471-2164-15-943;
RA   Teixeira M.M., de Almeida L.G., Kubitschek-Barreira P., Alves F.L.,
RA   Kioshima E.S., Abadio A.K., Fernandes L., Derengowski L.S., Ferreira K.S.,
RA   Souza R.C., Ruiz J.C., de Andrade N.C., Paes H.C., Nicola A.M.,
RA   Albuquerque P., Gerber A.L., Martins V.P., Peconick L.D., Neto A.V.,
RA   Chaucanez C.B., Silva P.A., Cunha O.L., de Oliveira F.F., dos Santos T.C.,
RA   Barros A.L., Soares M.A., de Oliveira L.M., Marini M.M.,
RA   Villalobos-Duno H., Cunha M.M., de Hoog S., da Silveira J.F., Henrissat B.,
RA   Nino-Vega G.A., Cisalpino P.S., Mora-Montes H.M., Almeida S.R.,
RA   Stajich J.E., Lopes-Bezerra L.M., Vasconcelos A.T., Felipe M.S.;
RT   "Comparative genomics of the major fungal agents of human and animal
RT   Sporotrichosis: Sporothrix schenckii and Sporothrix brasiliensis.";
RL   BMC Genomics 15:943-943(2014).
RN   [2] {ECO:0000313|EMBL:KJR89139.1, ECO:0000313|Proteomes:UP000033710}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=1099-18 {ECO:0000313|EMBL:KJR89139.1,
RC   ECO:0000313|Proteomes:UP000033710};
RX   PubMed=25480940;
RA   Teixeira Mde M., Rodrigues A.M., Tsui C.K., de Almeida L.G.,
RA   Van Diepeningen A.D., van den Ende B.G., Fernandes G.F., Kano R.,
RA   Hamelin R.C., Lopes-Bezerra L.M., Vasconcelos A.T., de Hoog S.,
RA   de Camargo Z.P., Felipe M.S.;
RT   "Asexual propagation of a virulent clone complex in a human and feline
RT   outbreak of sporotrichosis.";
RL   Eukaryot. Cell 14:158-169(2015).
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KJR89139.1}.
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DR   EMBL; AXCR01000001; KJR89139.1; -; Genomic_DNA.
DR   RefSeq; XP_016591815.1; XM_016732861.1.
DR   AlphaFoldDB; A0A0F2MJA5; -.
DR   GeneID; 27668138; -.
DR   KEGG; ssck:SPSK_06154; -.
DR   VEuPathDB; FungiDB:SPSK_06154; -.
DR   OrthoDB; 5311053at2759; -.
DR   Proteomes; UP000033710; Unassembled WGS sequence.
DR   CDD; cd00195; UBCc; 1.
DR   Gene3D; 3.10.110.10; Ubiquitin Conjugating Enzyme; 2.
DR   InterPro; IPR000608; UBQ-conjugat_E2.
DR   InterPro; IPR016135; UBQ-conjugating_enzyme/RWD.
DR   PANTHER; PTHR24067:SF292; CONJUGATING ENZYME, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G15040)-RELATED; 1.
DR   PANTHER; PTHR24067; UBIQUITIN-CONJUGATING ENZYME E2; 1.
DR   Pfam; PF00179; UQ_con; 2.
DR   SMART; SM00212; UBCc; 2.
DR   SUPFAM; SSF54495; UBC-like; 2.
DR   PROSITE; PS50127; UBC_2; 2.
PE   4: Predicted;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW   Transferase {ECO:0000256|ARBA:ARBA00022679};
KW   Ubl conjugation pathway {ECO:0000256|ARBA:ARBA00022786}.
FT   DOMAIN          4..164
FT                   /note="UBC core"
FT                   /evidence="ECO:0000259|PROSITE:PS50127"
FT   DOMAIN          293..446
FT                   /note="UBC core"
FT                   /evidence="ECO:0000259|PROSITE:PS50127"
SQ   SEQUENCE   464 AA;  53271 MW;  14B22C5188218947 CRC64;
     MSDQSIIRIS KELSDIQRNS DLSLAVACRD ADVRNVTTMI IGPPDTPYEF GFFEFTVKFS
     KDYPRKSPTV TALTTNSGRS RFNPNIYSNG RVCLSILGTW RGERGEEWSA AQGLESILLS
     IQSLMSSNPY ENEPGFEEAN DPSDKKNQSD YVQKIHHETM RVTVIMRLEE FLGLNHSRVG
     RLSQAERCNM IEDIDMDGLE ETVAPFEPFK DLCKRRFLWY YDTYLASVRK AKAEVPEGQM
     FVRMPFEGAN NTMEGRFCYG ELEKRLVAIK EALDEETNGW AAEGKQAVEQ IATVSVNLRR
     QFEQAVEAFK RDGTPHNIEL EDNNPFVWII TYFGKPMTNL DGGLFRIRLM LSPRFPQEQP
     RARFEVNIFH HRISGDGTPC YVVLPNKRED VRSHIEAIIE ALEEENPPYD PRTLVNPEAH
     KLFWGSPEDR KLYNRKLRRT VQQSLEGYVP GVPVSSWCLG QYPN
//