ID   A0A0F2SEF5_9FIRM        Unreviewed;       533 AA.
AC   A0A0F2SEF5;
DT   24-JUN-2015, integrated into UniProtKB/TrEMBL.
DT   24-JUN-2015, sequence version 1.
DT   27-MAR-2024, entry version 25.
DE   SubName: Full=3-hydroxyacyl-CoA dehydrogenase {ECO:0000313|EMBL:KJS48485.1};
DE   Flags: Fragment;
GN   ORFNames=VR66_13625 {ECO:0000313|EMBL:KJS48485.1};
OS   Peptococcaceae bacterium BRH_c23.
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Peptococcaceae.
OX   NCBI_TaxID=1629714 {ECO:0000313|EMBL:KJS48485.1, ECO:0000313|Proteomes:UP000033503};
RN   [1] {ECO:0000313|EMBL:KJS48485.1, ECO:0000313|Proteomes:UP000033503}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=BRH_c23 {ECO:0000313|EMBL:KJS48485.1};
RA   Bagnoud A., Chourey K., Hettich R.L., de Bruijn I., Andersson A.F.,
RA   Leupin O.X., Schwyn B., Bernier-Latmani R.;
RT   "Microbial metabolic network in the subsurface.";
RL   Submitted (MAR-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KJS48485.1}.
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DR   EMBL; LADV01000161; KJS48485.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A0F2SEF5; -.
DR   Proteomes; UP000033503; Unassembled WGS sequence.
DR   GO; GO:0070403; F:NAD+ binding; IEA:InterPro.
DR   GO; GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:InterPro.
DR   GO; GO:0044248; P:cellular catabolic process; IEA:UniProt.
DR   GO; GO:0006631; P:fatty acid metabolic process; IEA:InterPro.
DR   GO; GO:1901575; P:organic substance catabolic process; IEA:UniProt.
DR   Gene3D; 1.10.1040.50; -; 1.
DR   Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR   InterPro; IPR006176; 3-OHacyl-CoA_DH_NAD-bd.
DR   InterPro; IPR006108; 3HC_DH_C.
DR   InterPro; IPR008927; 6-PGluconate_DH-like_C_sf.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   PANTHER; PTHR48075; 3-HYDROXYACYL-COA DEHYDROGENASE FAMILY PROTEIN; 1.
DR   PANTHER; PTHR48075:SF7; 3-HYDROXYACYL-COA DEHYDROGENASE-RELATED; 1.
DR   Pfam; PF00725; 3HCDH; 1.
DR   Pfam; PF02737; 3HCDH_N; 1.
DR   SUPFAM; SSF48179; 6-phosphogluconate dehydrogenase C-terminal domain-like; 2.
DR   SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE   4: Predicted;
FT   DOMAIN          5..203
FT                   /note="3-hydroxyacyl-CoA dehydrogenase NAD binding"
FT                   /evidence="ECO:0000259|Pfam:PF02737"
FT   DOMAIN          206..303
FT                   /note="3-hydroxyacyl-CoA dehydrogenase C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF00725"
FT   NON_TER         533
FT                   /evidence="ECO:0000313|EMBL:KJS48485.1"
SQ   SEQUENCE   533 AA;  58100 MW;  6118ED6AF9D449DA CRC64;
     MQIHKVAVIG SGVMGSTIAA HLANAGIPSL LLDIVPSKLT AKEEAAGLTL EDRKVRNSLA
     EQNKTNMLKM NPAPFLVPEF AERIEVGNLS DDLGRLSEVD WVIEVVVERL DIKMDLFKKV
     AAQVRPGTIV TSNTSGISLK SMVEGLPESF TRYFLGTHFF NPPRYMKLLE IIPGPNTDQD
     VITFLCEFGE RVLGKGVVMA KDTPNFIANR IGAIGSPVLL KEMLRTGLTV DEVDALTGPV
     MGRPKSASFR TIDLVGLDTF IHSNNNVANG VPAEKDNFVL PEFIFTMLNN GWLGDKTNQG
     FYKKSKGPKG KVIEVLDIQT MTYGPQKSVN FASLEKAKAA RSLPEKLRTL VDGDDIGAEF
     AWNVLKPTLL YAATIVKDIA DDITGIDEGM RWGYNWEMGP FELWDALGVK ATADRIVAEG
     GTLPPLVEEL LAKGYESFYQ KTEAGQTAFY NAGTYHQKTV SPYSFSLKQA HKGGKVILGN
     AGASLVDLGD NVACLEFHSP NNSINADVVE MINKSLEEVE KNYLGLVIGN QGK
//