ID   A0A0F2TJD5_STRR3        Unreviewed;      1297 AA.
AC   A0A0F2TJD5;
DT   24-JUN-2015, integrated into UniProtKB/TrEMBL.
DT   24-JUN-2015, sequence version 1.
DT   27-MAR-2024, entry version 38.
DE   SubName: Full=Amino acid adenylation protein {ECO:0000313|EMBL:KJS62616.1};
GN   ORFNames=VM95_07380 {ECO:0000313|EMBL:KJS62616.1};
OS   Streptomyces rubellomurinus (strain ATCC 31215).
OC   Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC   Streptomycetaceae; Streptomyces.
OX   NCBI_TaxID=359131 {ECO:0000313|EMBL:KJS62616.1, ECO:0000313|Proteomes:UP000033699};
RN   [1] {ECO:0000313|EMBL:KJS62616.1, ECO:0000313|Proteomes:UP000033699}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 31215 {ECO:0000313|EMBL:KJS62616.1,
RC   ECO:0000313|Proteomes:UP000033699};
RA   Ju K.-S., Doroghazi J.R., Metcalf W.;
RL   Submitted (FEB-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KJS62616.1}.
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DR   EMBL; JZKH01000010; KJS62616.1; -; Genomic_DNA.
DR   RefSeq; WP_045693244.1; NZ_JZKH01000010.1.
DR   PATRIC; fig|359131.3.peg.7731; -.
DR   OrthoDB; 2472181at2; -.
DR   Proteomes; UP000033699; Unassembled WGS sequence.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR   GO; GO:0031177; F:phosphopantetheine binding; IEA:InterPro.
DR   GO; GO:0017000; P:antibiotic biosynthetic process; IEA:UniProt.
DR   GO; GO:0044249; P:cellular biosynthetic process; IEA:UniProt.
DR   GO; GO:1901362; P:organic cyclic compound biosynthetic process; IEA:UniProt.
DR   CDD; cd05930; A_NRPS; 1.
DR   CDD; cd02142; McbC_SagB-like_oxidoreductase; 1.
DR   Gene3D; 3.30.300.30; -; 2.
DR   Gene3D; 3.40.50.980; -; 2.
DR   Gene3D; 1.10.1200.10; ACP-like; 1.
DR   Gene3D; 3.40.50.1820; alpha/beta hydrolase; 1.
DR   Gene3D; 3.40.109.10; NADH Oxidase; 1.
DR   InterPro; IPR010071; AA_adenyl_domain.
DR   InterPro; IPR029058; AB_hydrolase.
DR   InterPro; IPR036736; ACP-like_sf.
DR   InterPro; IPR045851; AMP-bd_C_sf.
DR   InterPro; IPR020459; AMP-binding.
DR   InterPro; IPR020845; AMP-binding_CS.
DR   InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR   InterPro; IPR000415; Nitroreductase-like.
DR   InterPro; IPR020806; PKS_PP-bd.
DR   InterPro; IPR020802; PKS_thioesterase.
DR   InterPro; IPR009081; PP-bd_ACP.
DR   InterPro; IPR006162; Ppantetheine_attach_site.
DR   InterPro; IPR001031; Thioesterase.
DR   NCBIfam; TIGR01733; AA-adenyl-dom; 1.
DR   PANTHER; PTHR45527:SF1; FATTY ACID SYNTHASE; 1.
DR   PANTHER; PTHR45527; NONRIBOSOMAL PEPTIDE SYNTHETASE; 1.
DR   Pfam; PF00501; AMP-binding; 1.
DR   Pfam; PF00550; PP-binding; 1.
DR   Pfam; PF00975; Thioesterase; 1.
DR   PRINTS; PR00154; AMPBINDING.
DR   SMART; SM00823; PKS_PP; 1.
DR   SMART; SM00824; PKS_TE; 1.
DR   SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 1.
DR   SUPFAM; SSF47336; ACP-like; 1.
DR   SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
DR   PROSITE; PS00455; AMP_BINDING; 1.
DR   PROSITE; PS50075; CARRIER; 1.
DR   PROSITE; PS00012; PHOSPHOPANTETHEINE; 1.
PE   4: Predicted;
KW   Phosphopantetheine {ECO:0000256|ARBA:ARBA00022450};
KW   Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW   Reference proteome {ECO:0000313|Proteomes:UP000033699}.
FT   DOMAIN          939..1014
FT                   /note="Carrier"
FT                   /evidence="ECO:0000259|PROSITE:PS50075"
FT   REGION          1..22
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1297 AA;  140803 MW;  B66262F8D9B83488 CRC64;
     MLFTPSTPRT DTPAVPHARR APAGSALTDL LDRQVRVRSA SPAVVGDGRE LSYLELSDEA
     RRLAARLREL GAGPDGCVGL FAEPSTDLVA GAWGILYAGA GYLPLAPEYP EDRLRFMLED
     SGTRVVLTQE HLRERLTALA PRGTAVLTVE EARAGRARVE GEGPQPEELA YVIYTSGSTG
     RPKGVMIEHR SVVSQLRWLL GAGHLDPEAT VLQKTPMSFD AAQWEILAPA VGARVVAGAP
     GLHRDPEALV AAVQRHGVTT LQCVPTLLRA LLDTEGFTEC TGLTRVFAGG EALSRRLAHD
     LGRALPGAAL VNLYGPTECT INATAQLVDQ ADLGDGSGSV PIGRPVDNTQ CYILDEKLAP
     VGLGSVGELF IGGVQLARGY LNRPELTAQR FVPSPFAPAE RLYSTGDLAQ WNPDGTLQFA
     GRVDNQVKLR GHRVELDEIA RAIEEHTWVR RSAAVVTADE RTGHQNLVAC VELNPREAAL
     MDQGVHGGHH QSKASRLQVR AQLSDPGLRD PARLAGRERI DLPGRRETEN QRRAVFARKT
     YRFYEGGPVT RDDLLALLAP RPAGAFGRDL ALLSLPELGR ILRWFGQFHS TERLLPKYAY
     ASPGALYATQ LYLETGGLDG LAAGVYYYHP VDHALIRTAD APTRPQPYLT LHFAGKTAAI
     EPVYKNNIRE VLEFETGHML GVFEEVLPEY GLAVRPLGLD PAARERLDVA EEDHYLGAFE
     IGRGGGERRG IPVELYLQAH EGRIDGLPGG FYRYADGELT HLADEVVEAR HVIAINQAVY
     ARASFGVTAV GRAGAGEEWL EYIALGTQAH RLQRNGLGLG FMSSGYSSKT GHPLPAARRV
     DAILESAGLA AGPSYFFLGG KVSEDQIRGE DMREDAVHMK GPAEIIKDEL ATLLPDYMLP
     NRVLVLDALP LTANGKVDLR TLAASDTVRT ADVRGEYVAP SSEVERRLAG FWGRALNYED
     ASLTDEFFSV GGNSLIAVAL VNRINRELGT TLPLQVLFEC PRLGELAARV ERDLNGAAGT
     VSRLVPLNPD QRGPGDTRSP VFCWPGLGGY PMNLRVLGRE AGAGRAFYGV QSHGINAGET
     PYATIREMAA ADIAELRRVQ PEGPYTLWGY SFGARVAFEA AWQLEQAGQR VENLLLICPG
     NPKVRAREGE RWGRESSYAN PAYLSILFSV FAGTISGPDR ERCLAEAADE DGFVRFVHRM
     LPELDEELIR RITRIVGETY EFDYSFRELA ERRLDAPVTV FKAAGDDYSF IEGSSGYSAA
     PPTVVELAGD HYAVLKEHGV LELAAAIGAV EREAAGR
//