ID A0A0F3GIF1_9BACT Unreviewed; 426 AA.
AC A0A0F3GIF1;
DT 24-JUN-2015, integrated into UniProtKB/TrEMBL.
DT 24-JUN-2015, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE SubName: Full=Serine/threonine protein kinase with PASTA sensor(S) {ECO:0000313|EMBL:KJU81666.1};
GN ORFNames=MBAV_006136 {ECO:0000313|EMBL:KJU81666.1};
OS Candidatus Magnetobacterium bavaricum.
OC Bacteria; Nitrospirota; Nitrospiria; Nitrospirales; Nitrospiraceae;
OC Magnetobacterium.
OX NCBI_TaxID=29290 {ECO:0000313|EMBL:KJU81666.1, ECO:0000313|Proteomes:UP000033423};
RN [1] {ECO:0000313|EMBL:KJU81666.1, ECO:0000313|Proteomes:UP000033423}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=TM-1 {ECO:0000313|EMBL:KJU81666.1};
RA Kolinko S., Richter M., Glockner F.O., Brachmann A., Schuler D.;
RT "Single-cell genomics of uncultivated deep-branching MTB reveals a
RT conserved set of magnetosome genes.";
RL Submitted (FEB-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-
CC [protein]; Xref=Rhea:RHEA:17989, Rhea:RHEA-COMP:9863, Rhea:RHEA-
CC COMP:11604, ChEBI:CHEBI:15378, ChEBI:CHEBI:29999, ChEBI:CHEBI:30616,
CC ChEBI:CHEBI:83421, ChEBI:CHEBI:456216; EC=2.7.11.1;
CC Evidence={ECO:0000256|ARBA:ARBA00001433};
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + L-threonyl-[protein] = ADP + H(+) + O-phospho-L-
CC threonyl-[protein]; Xref=Rhea:RHEA:46608, Rhea:RHEA-COMP:11060,
CC Rhea:RHEA-COMP:11605, ChEBI:CHEBI:15378, ChEBI:CHEBI:30013,
CC ChEBI:CHEBI:30616, ChEBI:CHEBI:61977, ChEBI:CHEBI:456216;
CC EC=2.7.11.1; Evidence={ECO:0000256|ARBA:ARBA00000775};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KJU81666.1}.
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DR EMBL; LACI01002609; KJU81666.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0F3GIF1; -.
DR Proteomes; UP000033423; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0030553; F:cGMP binding; IEA:UniProtKB-KW.
DR GO; GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR GO; GO:0010506; P:regulation of autophagy; IEA:InterPro.
DR CDD; cd00038; CAP_ED; 1.
DR CDD; cd14014; STKc_PknB_like; 1.
DR Gene3D; 2.60.120.10; Jelly Rolls; 1.
DR Gene3D; 1.10.510.10; Transferase(Phosphotransferase) domain 1; 1.
DR InterPro; IPR045269; Atg1-like.
DR InterPro; IPR000595; cNMP-bd_dom.
DR InterPro; IPR018490; cNMP-bd_dom_sf.
DR InterPro; IPR011009; Kinase-like_dom_sf.
DR InterPro; IPR000719; Prot_kinase_dom.
DR InterPro; IPR014710; RmlC-like_jellyroll.
DR InterPro; IPR008271; Ser/Thr_kinase_AS.
DR PANTHER; PTHR24348:SF74; KINASE, PUTATIVE-RELATED; 1.
DR PANTHER; PTHR24348; SERINE/THREONINE-PROTEIN KINASE UNC-51-RELATED; 1.
DR Pfam; PF00027; cNMP_binding; 1.
DR Pfam; PF00069; Pkinase; 1.
DR SMART; SM00100; cNMP; 1.
DR SMART; SM00220; S_TKc; 1.
DR SUPFAM; SSF51206; cAMP-binding domain-like; 1.
DR SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
DR PROSITE; PS50042; CNMP_BINDING_3; 1.
DR PROSITE; PS50011; PROTEIN_KINASE_DOM; 1.
DR PROSITE; PS00108; PROTEIN_KINASE_ST; 1.
PE 4: Predicted;
KW cGMP {ECO:0000256|ARBA:ARBA00022535};
KW cGMP-binding {ECO:0000256|ARBA:ARBA00022992};
KW Kinase {ECO:0000313|EMBL:KJU81666.1};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022992};
KW Reference proteome {ECO:0000313|Proteomes:UP000033423};
KW Serine/threonine-protein kinase {ECO:0000313|EMBL:KJU81666.1};
KW Transferase {ECO:0000313|EMBL:KJU81666.1}.
FT DOMAIN 1..250
FT /note="Protein kinase"
FT /evidence="ECO:0000259|PROSITE:PS50011"
FT DOMAIN 282..383
FT /note="Cyclic nucleotide-binding"
FT /evidence="ECO:0000259|PROSITE:PS50042"
SQ SEQUENCE 426 AA; 47695 MW; 26C84501898E3DD1 CRC64;
MGTVYKGHDT IIDRIVAIKT IKIGVRGKAN DAVERFYHEA RIAGRLSHPN IALIYDVGED
NGTHYLVLEY VEGITLKEVI IENKELHPLD KVRILVLTAR TLHHAHQRGV IHRDIKPANI
MLLSDLQIKI MDFGIAMLAT QAGNTSEGLI GTPSYMSPEQ INGGEMDRQT DVFSMGALAY
EFVTGKKPFI AESMAALMDK ILTVNPIPPH IVNPQVSEYI SRFILKALEK DKPVRYQSAN
DFADALEVYL NQMEMEPSHD VVAVHGYDKT KLIESLKQKY TFFSDFTFEE LLKIFNISSK
KAYKKGDIIF KEGTLGTKLY VLISGKVKVT KVFPDSKEAT VLAELKPGEC FGEMAIMDNS
PRFATVTAET DCAMIAISEV ILRVSEPQLC LKLYKNLAAV LSEKLKKSDI KINELWGKIK
QLTSQT
//
