ID A0A0F3GV90_9BACT Unreviewed; 460 AA.
AC A0A0F3GV90;
DT 24-JUN-2015, integrated into UniProtKB/TrEMBL.
DT 24-JUN-2015, sequence version 1.
DT 27-MAR-2024, entry version 30.
DE RecName: Full=Exodeoxyribonuclease 7 large subunit {ECO:0000256|RuleBase:RU004355};
DE EC=3.1.11.6 {ECO:0000256|RuleBase:RU004355};
GN ORFNames=MBAV_002013 {ECO:0000313|EMBL:KJU85795.1};
OS Candidatus Magnetobacterium bavaricum.
OC Bacteria; Nitrospirota; Nitrospiria; Nitrospirales; Nitrospiraceae;
OC Magnetobacterium.
OX NCBI_TaxID=29290 {ECO:0000313|EMBL:KJU85795.1, ECO:0000313|Proteomes:UP000033423};
RN [1] {ECO:0000313|EMBL:KJU85795.1, ECO:0000313|Proteomes:UP000033423}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=TM-1 {ECO:0000313|EMBL:KJU85795.1};
RA Kolinko S., Richter M., Glockner F.O., Brachmann A., Schuler D.;
RT "Single-cell genomics of uncultivated deep-branching MTB reveals a
RT conserved set of magnetosome genes.";
RL Submitted (FEB-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=Exonucleolytic cleavage in either 5'- to 3'- or 3'- to 5'-
CC direction to yield nucleoside 5'-phosphates.; EC=3.1.11.6;
CC Evidence={ECO:0000256|RuleBase:RU004355};
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|RuleBase:RU004355}.
CC -!- SIMILARITY: Belongs to the XseA family.
CC {ECO:0000256|RuleBase:RU004355}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KJU85795.1}.
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DR EMBL; LACI01000853; KJU85795.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0F3GV90; -.
DR PATRIC; fig|29290.4.peg.2674; -.
DR Proteomes; UP000033423; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0009318; C:exodeoxyribonuclease VII complex; IEA:InterPro.
DR GO; GO:0008855; F:exodeoxyribonuclease VII activity; IEA:UniProtKB-EC.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0006308; P:DNA catabolic process; IEA:InterPro.
DR CDD; cd04489; ExoVII_LU_OBF; 1.
DR InterPro; IPR003753; Exonuc_VII_L.
DR InterPro; IPR020579; Exonuc_VII_lsu_C.
DR InterPro; IPR025824; OB-fold_nuc-bd_dom.
DR NCBIfam; TIGR00237; xseA; 1.
DR PANTHER; PTHR30008; EXODEOXYRIBONUCLEASE 7 LARGE SUBUNIT; 1.
DR PANTHER; PTHR30008:SF0; EXODEOXYRIBONUCLEASE 7 LARGE SUBUNIT; 1.
DR Pfam; PF02601; Exonuc_VII_L; 1.
DR Pfam; PF13742; tRNA_anti_2; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Exonuclease {ECO:0000256|ARBA:ARBA00022839, ECO:0000256|RuleBase:RU004355};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|RuleBase:RU004355};
KW Nuclease {ECO:0000256|ARBA:ARBA00022722, ECO:0000256|RuleBase:RU004355};
KW Reference proteome {ECO:0000313|Proteomes:UP000033423}.
FT DOMAIN 6..111
FT /note="OB-fold nucleic acid binding"
FT /evidence="ECO:0000259|Pfam:PF13742"
FT DOMAIN 137..428
FT /note="Exonuclease VII large subunit C-terminal"
FT /evidence="ECO:0000259|Pfam:PF02601"
FT COILED 273..300
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 460 AA; 51214 MW; 3F1EDCC1D1984BF8 CRC64;
MPKAILSLYE FNLYIRDIIS QTFSDAYYIT AEIASLNVDA KGHCYMELVE KDDTTIKAQL
RAAIWSSRYK GIAREFQTVT ARPLSKGMKI LIEASLTYHE RYGLSLNIAK LDPSYTLGDM
ARKRQEIIDR LVHEGLTDRN RSLVMPPVPQ RIAVISSLKA AGYEDFTKHL RGNSFGYGFR
VSLFAAVMQG DGAEASLIKA LLACEEGKDD IDVVVVVRGG GGAADLDCFD SYAIGRQIAM
MSMPVISGIG HERDRTVVDV VAHMTVKTPT AAAAFLIERL RAFEERIEAL AKALKSAAGT
VVLKNKYALN NYVKVIYGSG RLISRHMGVL TSMTDRLRLL LTRDVKDVRR RGNDLFTKTT
TLLFSAKRYI VRQAERLKAL DNSVTHLNPE NILKRGYSIT TLNGKALKSA DEVKTGDVIT
TQLMQGVIYS AVRPKSRIRV IDDKPKEVKD EGRKDLFSGY
//
