ID   A0A0F3RRA2_9LACO        Unreviewed;       453 AA.
AC   A0A0F3RRA2;
DT   24-JUN-2015, integrated into UniProtKB/TrEMBL.
DT   24-JUN-2015, sequence version 1.
DT   27-MAR-2024, entry version 29.
DE   SubName: Full=Sodium:solute symporter {ECO:0000313|EMBL:KJW12563.1};
GN   ORFNames=VC81_08785 {ECO:0000313|EMBL:KJW12563.1};
OS   Levilactobacillus spicheri.
OC   Bacteria; Bacillota; Bacilli; Lactobacillales; Lactobacillaceae;
OC   Levilactobacillus.
OX   NCBI_TaxID=216463 {ECO:0000313|EMBL:KJW12563.1, ECO:0000313|Proteomes:UP000033491};
RN   [1] {ECO:0000313|EMBL:KJW12563.1, ECO:0000313|Proteomes:UP000033491}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=LP38 {ECO:0000313|EMBL:KJW12563.1,
RC   ECO:0000313|Proteomes:UP000033491};
RA   Zheng J., Ganezle M.;
RL   Submitted (MAR-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651};
CC       Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}.
CC   -!- SIMILARITY: Belongs to the sodium:galactoside symporter (TC 2.A.2)
CC       family. {ECO:0000256|ARBA:ARBA00009617}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KJW12563.1}.
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DR   EMBL; JZCR01000019; KJW12563.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A0F3RRA2; -.
DR   PATRIC; fig|216463.3.peg.877; -.
DR   OrthoDB; 9764596at2; -.
DR   Proteomes; UP000033491; Unassembled WGS sequence.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0015293; F:symporter activity; IEA:InterPro.
DR   GO; GO:0008643; P:carbohydrate transport; IEA:InterPro.
DR   GO; GO:0006814; P:sodium ion transport; IEA:InterPro.
DR   CDD; cd17332; MFS_MelB_like; 1.
DR   Gene3D; 1.20.1250.20; MFS general substrate transporter like domains; 1.
DR   InterPro; IPR039672; MFS_2.
DR   InterPro; IPR036259; MFS_trans_sf.
DR   InterPro; IPR001927; Na/Gal_symport.
DR   NCBIfam; TIGR00792; gph; 1.
DR   PANTHER; PTHR11328:SF24; INNER MEMBRANE SYMPORTER YICJ-RELATED; 1.
DR   PANTHER; PTHR11328; MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN; 1.
DR   Pfam; PF13347; MFS_2; 1.
DR   SUPFAM; SSF103473; MFS general substrate transporter; 1.
PE   3: Inferred from homology;
KW   Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Symport {ECO:0000256|ARBA:ARBA00022847};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022847}.
FT   TRANSMEM        20..39
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        45..64
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        85..105
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        111..133
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        153..175
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        187..207
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        228..246
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        266..285
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        297..315
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        321..341
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        362..390
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        410..428
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
SQ   SEQUENCE   453 AA;  50796 MW;  B7F2C11D836EFF13 CRC64;
     MKKKAKQFLS NYEMFNYASL NFAQVLIYFL ISSYLLYFYT DVAKIPVTVA GVILLIARGF
     DAIDAPIWGA LIDITHSKYG RSRPYFLWVA FPFAISSVLM FWNPTLPYRE KIIWCAVTYI
     LSGILYTGIN TPLTSILPSL SRVPEERLKA NSWRLVGSQL GGFLINASCL PVVAFLGKGN
     DTKGFRFLIV IVAIVFLIIT LHAFTVVKER VPVSVEKVPI NKSIKAIKGN WPWVIIVLSN
     LFYWMAYTNR NSTLVYYFTY NFNDKGLVSL FNSLASLQLF MILLIPWLNK RFSKTQIWSA
     GFIIAILGQL IVLAAGHSIP IALFGWIFGN MGSGVAVTMP FSMLSQAVDF GEWKTGIHSS
     GILTALGSSF CIKMGSGLAG FIPSMILAHF GYVANQTQTA RSLFGIKLSF IWVSILLFVC
     ALIPVLFYGK YERMEDKIAS DLKLRHQQAK ENE
//