ID A0A0F4GBY8_9PEZI Unreviewed; 925 AA.
AC A0A0F4GBY8;
DT 24-JUN-2015, integrated into UniProtKB/TrEMBL.
DT 24-JUN-2015, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=DNA mismatch repair protein msh4 {ECO:0000313|EMBL:KJX93710.1};
GN ORFNames=TI39_contig4268g00009 {ECO:0000313|EMBL:KJX93710.1};
OS Zymoseptoria brevis.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Dothideomycetes;
OC Dothideomycetidae; Mycosphaerellales; Mycosphaerellaceae; Zymoseptoria.
OX NCBI_TaxID=1047168 {ECO:0000313|EMBL:KJX93710.1, ECO:0000313|Proteomes:UP000033647};
RN [1] {ECO:0000313|EMBL:KJX93710.1, ECO:0000313|Proteomes:UP000033647}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Zb18110 {ECO:0000313|EMBL:KJX93710.1,
RC ECO:0000313|Proteomes:UP000033647};
RA Grandaubert J., Bhattacharyya A., Stukenbrock E.H.;
RT "RNA-seq based gene annotation and comparative genomics of four
RT Zymoseptoria species reveal species-specific pathogenicity related genes
RT and transposable element activity.";
RL Submitted (MAR-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the DNA mismatch repair MutS family.
CC {ECO:0000256|ARBA:ARBA00006271}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KJX93710.1}.
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DR EMBL; LAFY01004227; KJX93710.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0F4GBY8; -.
DR STRING; 1047168.A0A0F4GBY8; -.
DR OrthoDB; 168255at2759; -.
DR Proteomes; UP000033647; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0140664; F:ATP-dependent DNA damage sensor activity; IEA:InterPro.
DR GO; GO:0030983; F:mismatched DNA binding; IEA:InterPro.
DR GO; GO:0051321; P:meiotic cell cycle; IEA:UniProtKB-KW.
DR GO; GO:0006298; P:mismatch repair; IEA:InterPro.
DR Gene3D; 1.10.1420.10; -; 2.
DR Gene3D; 3.30.420.110; MutS, connector domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR011184; DNA_mismatch_repair_Msh2.
DR InterPro; IPR000432; DNA_mismatch_repair_MutS_C.
DR InterPro; IPR007861; DNA_mismatch_repair_MutS_clamp.
DR InterPro; IPR007696; DNA_mismatch_repair_MutS_core.
DR InterPro; IPR036187; DNA_mismatch_repair_MutS_sf.
DR InterPro; IPR007860; DNA_mmatch_repair_MutS_con_dom.
DR InterPro; IPR036678; MutS_con_dom_sf.
DR InterPro; IPR045076; MutS_family.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR11361; DNA MISMATCH REPAIR PROTEIN MUTS FAMILY MEMBER; 1.
DR PANTHER; PTHR11361:SF21; MUTS PROTEIN HOMOLOG 4; 1.
DR Pfam; PF05188; MutS_II; 1.
DR Pfam; PF05192; MutS_III; 1.
DR Pfam; PF05190; MutS_IV; 1.
DR Pfam; PF00488; MutS_V; 1.
DR PIRSF; PIRSF005813; MSH2; 1.
DR SMART; SM00534; MUTSac; 1.
DR SMART; SM00533; MUTSd; 1.
DR SUPFAM; SSF53150; DNA repair protein MutS, domain II; 1.
DR SUPFAM; SSF48334; DNA repair protein MutS, domain III; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS00486; DNA_MISMATCH_REPAIR_2; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Meiosis {ECO:0000256|ARBA:ARBA00023254};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000033647}.
FT DOMAIN 678..694
FT /note="DNA mismatch repair proteins mutS family"
FT /evidence="ECO:0000259|PROSITE:PS00486"
FT REGION 1..69
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 855..925
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 7..51
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 855..882
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 899..925
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 925 AA; 103002 MW; A868F5F9A586ACC8 CRC64;
MPPPSTARSA RSTSSRASTS YDTTATGNRP GTSNPLTTTY EYTTGTESRP YTGHPSAGRP
GTARPRTGVS TLGVENQDII CAVSESRGVS PSVGLAFLNL DTGEAVLSQF SDSQTYVRTI
HKLAVFNPTT ILAVSSSAQP KSKLFSIIED SIQQDLDSNV TLLDRRYWSE TAGLDYIHHL
AFPEDVENLK TVLNGNYFAV CSFAAVLKFI EHGLSKVFPA RSLRVKYEPS EGSMMIDLAT
MRSLELVQNL QNPKSKDCLF GQLNETLTPM GARLLRSNIL QPVTNPETLN KRYEAVEELS
TKEDTFFAVR ETLKPFLDAD KTLTQLILSP VQITVTTTEQ SINNVIMLKQ FVALISPVYE
ALTGSRSDML STIRKICAPG NIEPVQSLIA GAINEDTTYA KKPLDLRNQR TYAVRSGVNG
LLDVARQTYK ESMTDALQHI DEVAQEHSLP LLTKFDNNRQ FYLHLKAEEL EDRNLPEIFI
NSYRKKDIIE CQTLDLVKLN QKIRDAHMEV LLMSDKAIRD LIDAVREHMS SLFRVCESIA
MLDMLAAFAH AVSTCDYIRP QLNSTTLAIH SGRHPIREKI HMTQKFVPND VYATQQTRFQ
IITGANMSGK STYIRSVALI TIMAQVGSFV PASYASLPII HHLFARISID DNIEANVSSF
AAEMRETAFI LHNITPHSMA IVDELGRGTS TRDGLAIAIA IAEALVASRA LVWFATHFRD
LTSILAERNG VVNLHLAIDM SPEDHRMEML YRIASGSEQV SHYGLALARI VPLPEDIIPF
AEQVSRTLEE RGLAKQERSM GVVKARRRKL MLNLKEHLVQ ARESRMDDQA LKKWLGDLQG
EFVVRMTALD EEAREVMRRE DEDESVGRGE EREDGRDGVE EEMMSMGDDE DDTGRATVGT
GEEQATITHS TRAETISSRE SSEMS
//
