ID A0A0F4GYS4_9PEZI Unreviewed; 1275 AA.
AC A0A0F4GYS4;
DT 24-JUN-2015, integrated into UniProtKB/TrEMBL.
DT 24-JUN-2015, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE SubName: Full=DUF221-domain-containing protein {ECO:0000313|EMBL:KJY02183.1};
GN ORFNames=TI39_contig83g00004 {ECO:0000313|EMBL:KJY02183.1};
OS Zymoseptoria brevis.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Dothideomycetes;
OC Dothideomycetidae; Mycosphaerellales; Mycosphaerellaceae; Zymoseptoria.
OX NCBI_TaxID=1047168 {ECO:0000313|EMBL:KJY02183.1, ECO:0000313|Proteomes:UP000033647};
RN [1] {ECO:0000313|EMBL:KJY02183.1, ECO:0000313|Proteomes:UP000033647}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Zb18110 {ECO:0000313|EMBL:KJY02183.1,
RC ECO:0000313|Proteomes:UP000033647};
RA Grandaubert J., Bhattacharyya A., Stukenbrock E.H.;
RT "RNA-seq based gene annotation and comparative genomics of four
RT Zymoseptoria species reveal species-specific pathogenicity related genes
RT and transposable element activity.";
RL Submitted (MAR-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the CSC1 (TC 1.A.17) family.
CC {ECO:0000256|ARBA:ARBA00007779}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KJY02183.1}.
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DR EMBL; LAFY01000080; KJY02183.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0F4GYS4; -.
DR OrthoDB; 54187at2759; -.
DR Proteomes; UP000033647; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005227; F:calcium-activated cation channel activity; IEA:InterPro.
DR InterPro; IPR045122; Csc1-like.
DR InterPro; IPR003864; CSC1/OSCA1-like_7TM.
DR InterPro; IPR027815; CSC1/OSCA1-like_cyt.
DR InterPro; IPR032880; Csc1/OSCA1-like_N.
DR InterPro; IPR022257; PHM7_ext.
DR PANTHER; PTHR13018; PROBABLE MEMBRANE PROTEIN DUF221-RELATED; 1.
DR PANTHER; PTHR13018:SF20; SPORULATION-SPECIFIC PROTEIN 75; 1.
DR Pfam; PF14703; PHM7_cyt; 2.
DR Pfam; PF12621; PHM7_ext; 1.
DR Pfam; PF02714; RSN1_7TM; 1.
DR Pfam; PF13967; RSN1_TM; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000033647};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 36..60
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 120..139
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 166..185
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 710..735
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 755..780
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 801..821
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 904..937
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 957..983
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 990..1012
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 38..187
FT /note="CSC1/OSCA1-like N-terminal transmembrane"
FT /evidence="ECO:0000259|Pfam:PF13967"
FT DOMAIN 211..295
FT /note="CSC1/OSCA1-like cytosolic"
FT /evidence="ECO:0000259|Pfam:PF14703"
FT DOMAIN 606..697
FT /note="CSC1/OSCA1-like cytosolic"
FT /evidence="ECO:0000259|Pfam:PF14703"
FT DOMAIN 708..981
FT /note="CSC1/OSCA1-like 7TM region"
FT /evidence="ECO:0000259|Pfam:PF02714"
FT DOMAIN 1173..1266
FT /note="10TM putative phosphate transporter extracellular
FT tail"
FT /evidence="ECO:0000259|Pfam:PF12621"
FT REGION 277..329
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 342..361
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 429..570
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1069..1111
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 277..314
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 440..486
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 497..511
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 516..533
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 543..570
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1069..1095
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1275 AA; 143404 MW; DF0A60688CE8B1AD CRC64;
MDPGATTPSS NCTETNWFLQ IFNCPRSVEG SSPTTIGALV AALAVSFASL GGQTLIFTIL
RLKLTRIYRP KSYLVPERER VPPPPGGIIG WIYPLWTTSN LTLIQKCGLD AYFFLRYLRM
LLKIFFPMAI LCLPVLLPIN NSGGNGLQGL DKLTVANIIA TKGDRLWTHL VLAIIFIGWL
CYVVFMELRG YIRVRQAYLT SPQHRIRASA TTVLVTGIPR KWLTLEALSG LYDVFPGGIR
NIWINRNYDA LAEKVSDRES IAKSLENAET NLIKKCREKH AEAEKKRAKK EGRRTKSKEQ
QKQDKADEDA AAERLAEGQG VSAGAHHETQ HGMQDILDED DRQEDNYTSP GHKPRGFAGK
FGQGIGNFGK GVTKFGGRVV GDVDTTLHKA GTDLNRNVDV LNTGGIGGGF VVDDSLYDSP
AAQRSNQNLR ADGLTGLRKP GQTAKQQLDG ANNERSQMQA RPRNDSSAIA DARGRNSSNS
DDTLGGPNIR MTRPSADEPR STMETEKPQA QKAQRKPWNF LKNQDNNLVL PSPQPHQAEG
ENGFPLHHSE KPQFEGKGKG RKKKDEKPTN EEYDCAFDEE WDEDQDEEPY WRRYIEPKDR
ETMRLPLFSP AWFPALPLVG KKVDRIYHLR RELARLNLEI EEDQNDPDKF PHMNSAFIQF
NHQIAAHMCC QSLSHHIPQQ MAPRIVEISP DDVIWDNMSI KWWERYLRTF IVLLVCAGLI
ILYAVPVALT GLISNVGQLA TFAPWLRWLN DAPKWVISAI EGILPPLLLA LILALVPVIF
RLMIQQKGVA TGNAKEMGVQ TWYFAFLFIQ VFFVVTLSTG FSEFVNNFAN NPGEVVETLG
KTLPQSSNYF FTYLTVQALS NSASNLLQTG SLFGWFILAP LLDSTPRAKW KRQTELNRVQ
WGSFFPPFTN FAVIGIIYSI LSPLILVFML LIFGLFWVVY RYNVLFVYQF KNDTGGLLFP
VAINQLFVGV YFLEVCLIGI FFTTIENGTV VTLPQGIIMI LVLVATVGYQ ILMNSAFNPL
FQYLPITLED EAVIRDEEFA RAQASKFAPL TQQEEQEAED PRDIQDVLER KERNEHDQDV
AAEDSERRNI EEHRRPSAAP PTTSSSPNEK AKAWYHRTEA TPAALDPEKW KHVGPEAVAR
LRYLADGKPV ESQNANANTN DPESQKTVGD VLFAGYADEL EDLTPDERDL LVRFAFQHSA
LRAKRPVVWI PRDTLGVSDD EIRRAKRMST ARVGAEGEER VNIWMSNEGT ALDGKGRVVF
RRSPPDFRSL DLIAL
//
