ID A0A0F4J4W3_9ACTN Unreviewed; 486 AA.
AC A0A0F4J4W3;
DT 24-JUN-2015, integrated into UniProtKB/TrEMBL.
DT 24-JUN-2015, sequence version 1.
DT 27-MAR-2024, entry version 33.
DE SubName: Full=Glutamate synthase {ECO:0000313|EMBL:KJY28859.1};
DE EC=1.4.1.13 {ECO:0000313|EMBL:KJY28859.1};
GN Name=gltD {ECO:0000313|EMBL:KJY28859.1};
GN ORFNames=VR44_24340 {ECO:0000313|EMBL:KJY28859.1};
OS Streptomyces katrae.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=68223 {ECO:0000313|EMBL:KJY28859.1, ECO:0000313|Proteomes:UP000033551};
RN [1] {ECO:0000313|EMBL:KJY28859.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NRRL ISP-5550 {ECO:0000313|EMBL:KJY28859.1};
RA Ju K.-S., Doroghazi J.R., Metcalf W.;
RL Submitted (FEB-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- PATHWAY: Amino-acid biosynthesis. {ECO:0000256|ARBA:ARBA00029440}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KJY28859.1}.
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DR EMBL; JZWV01000697; KJY28859.1; -; Genomic_DNA.
DR RefSeq; WP_045949720.1; NZ_JZWV01000697.1.
DR AlphaFoldDB; A0A0F4J4W3; -.
DR STRING; 68223.GCA_002028425_01957; -.
DR PATRIC; fig|68223.7.peg.850; -.
DR eggNOG; COG0493; Bacteria.
DR OrthoDB; 9803192at2; -.
DR Proteomes; UP000033551; Unassembled WGS sequence.
DR GO; GO:0004355; F:glutamate synthase (NADPH) activity; IEA:UniProtKB-EC.
DR GO; GO:0051536; F:iron-sulfur cluster binding; IEA:InterPro.
DR GO; GO:0006537; P:glutamate biosynthetic process; IEA:UniProtKB-KW.
DR Gene3D; 1.10.1060.10; Alpha-helical ferredoxin; 1.
DR Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 2.
DR InterPro; IPR028261; DPD_II.
DR InterPro; IPR036188; FAD/NAD-bd_sf.
DR InterPro; IPR023753; FAD/NAD-binding_dom.
DR InterPro; IPR006005; Glut_synth_ssu1.
DR InterPro; IPR009051; Helical_ferredxn.
DR NCBIfam; TIGR01317; GOGAT_sm_gam; 1.
DR PANTHER; PTHR43100; GLUTAMATE SYNTHASE [NADPH] SMALL CHAIN; 1.
DR PANTHER; PTHR43100:SF1; GLUTAMATE SYNTHASE [NADPH] SMALL CHAIN; 1.
DR Pfam; PF14691; Fer4_20; 1.
DR Pfam; PF07992; Pyr_redox_2; 1.
DR PRINTS; PR00419; ADXRDTASE.
DR SUPFAM; SSF46548; alpha-helical ferredoxin; 1.
DR SUPFAM; SSF51971; Nucleotide-binding domain; 2.
PE 4: Predicted;
KW Amino-acid biosynthesis {ECO:0000256|ARBA:ARBA00022605};
KW Glutamate biosynthesis {ECO:0000256|ARBA:ARBA00023164};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002,
KW ECO:0000313|EMBL:KJY28859.1}.
FT DOMAIN 39..131
FT /note="Dihydroprymidine dehydrogenase"
FT /evidence="ECO:0000259|Pfam:PF14691"
FT DOMAIN 146..456
FT /note="FAD/NAD(P)-binding"
FT /evidence="ECO:0000259|Pfam:PF07992"
SQ SEQUENCE 486 AA; 52511 MW; 5E38648A7E64B276 CRC64;
MADPKGFLTT PRETACTRPV AERVKDWNEV YVKGSLLPII SKQAGRCMDC GIPFCHNGCP
LGNLIPEWND YAYREDWSAA AERLHATNNF PEFTGRLCPA PCESACVLGI NQPAVTIKNV
EVSIIDQAWD NGDVTPQAPD RLSGKTVAVI GSGPAGLAAA QQLTRAGHTV VVYERADRIG
GLLRYGIPEF KMEKVHINRR IEQMRAEGTK FRTGIEVGRD ITATDLRKRF DAVVVAAGAT
VSRDLPVPGR DLKGIHFAME YLPLANKVQE GDFMAPPITA EGKHVVVIGG GDTGADCVGT
AHRQGALSVT QLEIMPRPSE DRPAAMPWPT FPMLYKVTSA HEEGGERIYS VSTTHFEGDE
DGNVQALHLV EVEFIDGKLT QKPGTERVLP AQLVTLAMGF TGTDQSNGLV EQFGVELDER
GNIARDASYA TNADGVFVAG DAGRGQSLIV WAIAEGRSAA RGVDRYLTGT STLPYPVKPT
DRSLMV
//
