ID   A0A0F4J7Y2_9ACTN        Unreviewed;       841 AA.
AC   A0A0F4J7Y2;
DT   24-JUN-2015, integrated into UniProtKB/TrEMBL.
DT   24-JUN-2015, sequence version 1.
DT   27-MAR-2024, entry version 35.
DE   SubName: Full=NDP-hexose 4-ketoreductase {ECO:0000313|EMBL:KJY29873.1};
GN   ORFNames=VR44_21785 {ECO:0000313|EMBL:KJY29873.1};
OS   Streptomyces katrae.
OC   Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC   Streptomycetaceae; Streptomyces.
OX   NCBI_TaxID=68223 {ECO:0000313|EMBL:KJY29873.1, ECO:0000313|Proteomes:UP000033551};
RN   [1] {ECO:0000313|EMBL:KJY29873.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NRRL ISP-5550 {ECO:0000313|EMBL:KJY29873.1};
RA   Ju K.-S., Doroghazi J.R., Metcalf W.;
RL   Submitted (FEB-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KJY29873.1}.
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DR   EMBL; JZWV01000609; KJY29873.1; -; Genomic_DNA.
DR   RefSeq; WP_045949250.1; NZ_JZWV01000609.1.
DR   AlphaFoldDB; A0A0F4J7Y2; -.
DR   STRING; 68223.GCA_002028425_03150; -.
DR   PATRIC; fig|68223.7.peg.237; -.
DR   eggNOG; COG0542; Bacteria.
DR   OrthoDB; 9803641at2; -.
DR   Proteomes; UP000033551; Unassembled WGS sequence.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR   CDD; cd00009; AAA; 1.
DR   CDD; cd19499; RecA-like_ClpB_Hsp104-like; 1.
DR   Gene3D; 1.10.8.60; -; 2.
DR   Gene3D; 1.10.1780.10; Clp, N-terminal domain; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR   Gene3D; 4.10.860.10; UVR domain; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR003959; ATPase_AAA_core.
DR   InterPro; IPR019489; Clp_ATPase_C.
DR   InterPro; IPR036628; Clp_N_dom_sf.
DR   InterPro; IPR004176; Clp_R_dom.
DR   InterPro; IPR001270; ClpA/B.
DR   InterPro; IPR018368; ClpA/B_CS1.
DR   InterPro; IPR041546; ClpA/ClpB_AAA_lid.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR001943; UVR_dom.
DR   PANTHER; PTHR11638; ATP-DEPENDENT CLP PROTEASE; 1.
DR   PANTHER; PTHR11638:SF193; CHAPERONE PROTEIN CLPB; 1.
DR   Pfam; PF00004; AAA; 1.
DR   Pfam; PF07724; AAA_2; 1.
DR   Pfam; PF17871; AAA_lid_9; 1.
DR   Pfam; PF02861; Clp_N; 2.
DR   Pfam; PF10431; ClpB_D2-small; 1.
DR   PRINTS; PR00300; CLPPROTEASEA.
DR   SMART; SM00382; AAA; 2.
DR   SMART; SM01086; ClpB_D2-small; 1.
DR   SUPFAM; SSF81923; Double Clp-N motif; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR   PROSITE; PS51903; CLP_R; 1.
DR   PROSITE; PS00870; CLPAB_1; 1.
DR   PROSITE; PS50151; UVR; 1.
PE   4: Predicted;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW   Chaperone {ECO:0000256|ARBA:ARBA00023186};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737, ECO:0000256|PROSITE-
KW   ProRule:PRU01251}.
FT   DOMAIN          2..144
FT                   /note="Clp R"
FT                   /evidence="ECO:0000259|PROSITE:PS51903"
FT   DOMAIN          423..458
FT                   /note="UVR"
FT                   /evidence="ECO:0000259|PROSITE:PS50151"
FT   REGION          815..841
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   841 AA;  92870 MW;  E488A190FCE660F2 CRC64;
     MFERFTDRAR RVVVLAQEEA RMLNHNYIGT EHILLGLIHE GEGVAAKALE SLGISLEAVR
     QQVEEIIGQG QQAPSGHIPF TPRAKKVLEL SLREALQLGH NYIGTEHILL GLIREGEGVA
     AQVLVKLGAD LNRVRQQVIQ LLSGYTGGGK ESATAGGPAE GTPSTSLVLD QFGRNLTQAA
     RESKLDPVIG REKEIERVMQ VLSRRTKNNP VLIGEPGVGK TAVVEGLAQA IVKGEVPETL
     KDKHLYTLDL GALVAGSRYR GDFEERLKKV LKEIRTRGDI ILFIDELHTL VGAGAAEGAI
     DAASILKPML ARGELQTIGA TTLDEYRKHL EKDAALERRF QPIQVAEPSL PHTIEILKGL
     RDRYEAHHRV SITDEALVQA ATLADRYISD RFLPDKAIDL IDEAGSRMRI RRMTAPPDLR
     EFDEKIAAVR RDKESAIDSQ DFEKAASLRD SEKQLLAAKS KREKEWKAGD MDVVAEVDGE
     LIAEVLATAT GIPVFKLTEE ESSRLLRMED ELHKRVIGQK DAIKALSQAI RRTRAGLKDP
     KRPGGSFIFA GPSGVGKTEL SKTLAEFLFG DEDALISLDM SEFSEKHTVS RLFGSPPGYV
     GYEEGGQLTE KVRRKPFSVV LFDEVEKAHP DIFNSLLQIL EDGRLTDSQG RVVDFKNTVI
     IMTTNLGTRD ISKGFNLGFA AQGDVKTGYD RMKAKVNEEL KQHFRPEFLN RVDDTVVFHQ
     LSQEDIIQIV DLMIAKVDER LKDRDMGIEL SGDAKLLLAK RGYDPIMGAR PLRRTIQREI
     EDLLSEKILF GELRPGHIVV VGVEGEGDEA KFTFRGEEKS ALPDLPPIEA TGSGPDLSKG
     A
//