ID A0A0F4NQM1_9VIBR Unreviewed; 201 AA.
AC A0A0F4NQM1;
DT 24-JUN-2015, integrated into UniProtKB/TrEMBL.
DT 24-JUN-2015, sequence version 1.
DT 24-JAN-2024, entry version 30.
DE RecName: Full=Ubiquinone biosynthesis accessory factor UbiJ {ECO:0000256|HAMAP-Rule:MF_02215};
GN Name=ubiJ {ECO:0000256|HAMAP-Rule:MF_02215};
GN ORFNames=TW81_04300 {ECO:0000313|EMBL:KJY84406.1};
OS Vibrio galatheae.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Vibrionales; Vibrionaceae;
OC Vibrio.
OX NCBI_TaxID=579748 {ECO:0000313|EMBL:KJY84406.1, ECO:0000313|Proteomes:UP000033673};
RN [1] {ECO:0000313|EMBL:KJY84406.1, ECO:0000313|Proteomes:UP000033673}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=S2757 {ECO:0000313|EMBL:KJY84406.1,
RC ECO:0000313|Proteomes:UP000033673};
RX PubMed=25879706; DOI=10.1186/s12864-015-1365-z;
RA Machado H., Sonnenschein E.C., Melchiorsen J., Gram L.;
RT "Genome mining reveals unlocked bioactive potential of marine Gram-negative
RT bacteria.";
RL BMC Genomics 16:158-158(2015).
CC -!- FUNCTION: Required for ubiquinone (coenzyme Q) biosynthesis. Binds
CC hydrophobic ubiquinone biosynthetic intermediates via its SCP2 domain
CC and is essential for the stability of the Ubi complex. May constitute a
CC docking platform where Ubi enzymes assemble and access their SCP2-bound
CC polyprenyl substrates. {ECO:0000256|HAMAP-Rule:MF_02215}.
CC -!- PATHWAY: Cofactor biosynthesis; ubiquinone biosynthesis.
CC {ECO:0000256|HAMAP-Rule:MF_02215}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_02215}.
CC -!- SIMILARITY: Belongs to the UbiJ family. {ECO:0000256|HAMAP-
CC Rule:MF_02215}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KJY84406.1}.
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DR EMBL; JXXV01000008; KJY84406.1; -; Genomic_DNA.
DR RefSeq; WP_045954498.1; NZ_JXXV01000008.1.
DR AlphaFoldDB; A0A0F4NQM1; -.
DR STRING; 579748.TW81_04300; -.
DR PATRIC; fig|579748.3.peg.882; -.
DR OrthoDB; 5801225at2; -.
DR UniPathway; UPA00232; -.
DR Proteomes; UP000033673; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0032150; P:ubiquinone biosynthetic process from chorismate; IEA:InterPro.
DR Gene3D; 3.30.1050.10; SCP2 sterol-binding domain; 1.
DR HAMAP; MF_02215; UbiJ; 1.
DR InterPro; IPR003033; SCP2_sterol-bd_dom.
DR InterPro; IPR036527; SCP2_sterol-bd_dom_sf.
DR InterPro; IPR038989; UbiJ.
DR PANTHER; PTHR38693:SF1; UBIQUINONE BIOSYNTHESIS ACCESSORY FACTOR UBIJ; 1.
DR PANTHER; PTHR38693; UBIQUINONE BIOSYNTHESIS PROTEIN UBIJ; 1.
DR Pfam; PF02036; SCP2; 1.
DR SUPFAM; SSF55718; SCP-like; 1.
PE 3: Inferred from homology;
KW Cytoplasm {ECO:0000256|HAMAP-Rule:MF_02215};
KW Reference proteome {ECO:0000313|Proteomes:UP000033673};
KW Ubiquinone biosynthesis {ECO:0000256|HAMAP-Rule:MF_02215}.
FT DOMAIN 15..111
FT /note="SCP2"
FT /evidence="ECO:0000259|Pfam:PF02036"
SQ SEQUENCE 201 AA; 22701 MW; F2309D3405B26FF0 CRC64;
MPFEPLVTAV IETTLNTLIN DDPELGRRLA RLKGQVIQVH FKELDKTLTF IFSQQIDVLA
NYEGQPDCYL SLNLSILPEL REQSNITKLI KQDKLVLEGD IQLAQKFSQL MTDCKPDVEE
WLSRVTGDVV AHTVVQGVAN VGQFLKSQAQ KHQSHMAQVL TEEWQIAPAP LEVAHFCDQV
DEVKSQASRI EAKLNQLLER A
//
